第 1 到 23 筆結果，共 23 筆。
| 公開日期 | 題名 | 作者 | 關聯 | scopus | WOS | 全文 | |
|---|---|---|---|---|---|---|---|
| 1 | 2024 | Dual-targeting compounds possessing enhanced anticancer activity via microtubule disruption and histone deacetylase inhibition | Tseng, YW; Yang, TJ; Hsu, YL; Liu, JH; Tseng, YC; Hsu, TW; Lu, Y; Pan, SH; , Cheng, TR ; Fang, JM | European journal of medicinal chemistry 265, 116042 | |||
| 2 | 2023 | Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera | Tseng, YL; Lu, PC; Lee, CC; He, RY; Huang, YA; Tseng, YC; Cheng, TR ; Huang, JJ ; Fang, JM | Journal of biomedical science 30(1), 27 | |||
| 3 | 2022 | Photoaffinity labeling of benzophenone-containing salicylanilide compounds to give an insight into the mechanism in disrupting peptidoglycan formation | Chuang, HC; Liu, MF; Wu, HY; Wu, YT ; Cheng, TR ; Fang, JM | BIOORGANIC & MEDICINAL CHEMISTRY 67, 116819 | |||
| 4 | 2022 | Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agents | Chen, Wei-An; Chen, Yu-Hsin; Hsieh, Chiao-Yun; Hung, Pi-Fang; Chen, Chiao-Wen; Chen, Chien-Hung; Lin, Jung-Lee ; Cheng, Ting-Jen R. ; Hsu, Tsui-Ling ; Wu, Ying-Ta ; Shen, Chia-Ning ; Cheng, Wei-Chieh | Chemical Science 13(21), 6233-6243 | |||
| 5 | 2022 | Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models | Huang, HY; Liao, HY; Chen, X; Wang, SW; Cheng, CW; Shahed-Al-Mahmud, M; Liu, YM; Mohapatra, A; Chen, TH; Lo, JM; Wu, YM; Ma, HH; Chang, YH; Tsai, HY; Chou, YC ; Hsueh, YP ; Tsai, CY ; Huang, PY; Chang, SY; Chao, TL; Kao, HC; Tsai, YM; Chen, YH ; Wu, CY ; Jan, JT ; Cheng, TR ; Lin, KI ; Ma, C ; Wong, CH | Science Translational Medicine 14(639), eabm0899 | |||
| 6 | 2021 | A non-neutralizing antibody broadly protects against influenza virus infection by engaging effector cells | Ko, YA; Yu, YH; Wu, YF; Tseng, YC; Chen, CL; Goh, KS; Liao, HY; Chen, TH; Cheng, TR ; Yang, AS ; Wong, CH ; Ma, C ; Lin, KI | PLoS pathogens 17(8), e1009724 | |||
| 7 | 2021 | Impact of glycosylation on a broad-spectrum vaccine against SARS-CoV-2 | Han-Yi Huang; Hsin-Yu Liao; Xiaorui Chen; Szu-Wen Wang; Cheng-Wei Cheng; Md. Shahed-Al-Mahmud; Ting-Hua Chen; Jennifer M. Lo; Yo-Min Liu; Yi-Min Wu; Hsiu-Hua Ma; Yi-Hsuan Chang; Ho-Yang Tsai; Yu-Chi Chou ; Yi-Ping Hsueh ; Ching-Yen Tsai ; Pau-Yi Huang; Sui-Yuan Chang; Tai-Ling Chao; Han-Chieh Kao; Ya-Min Tsai; Yen-Hui Chen ; Chung-Yi Wu ; Jia-Tsrong Jan ; Ting-Jen Rachel Cheng ; Kuo-I Lin; Che Ma ; Chi-Huey Wong | bioRxiv | |||
| 8 | 2021 | Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses | Chang, SY; Huang, KY; Chao, TL; Kao, HC; Pang, YH; Lu, L; Chiu, CL; Huang, HC; Cheng, TR ; Fang, JM; Yang, PC | Scientific reports 11, 8692 | |||
| 9 | 2021 | Immunogenicity Evaluation of N-Glycans Recognized by HIV Broadly Neutralizing Antibodies | Shivatare, Sachin S.; Cheng, Ting-Jen Rachel ; Cheng, Yang-Yu; Shivatare, Vidya S.; Tsai, Tsung-I; Chuang, Hong-Yang; Wu, Chung-Yi ; Wong, Chi-Huey | ACS Chemical Biology 16(10), 2016-2025 | |||
| 10 | 2020 | Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein | Chia-Yi Lin; Hsin-Yi Wu; Yuan-Ling Hsu; Ting-Jen Rachel Cheng ; Jyung-Hurng Liu; Rou-Jie Huang; Tzu Hung Hsiao; Chia-Jen Wang; Pei-Fang Hung; Albert Lan; Szu-Hua Pan; Rong-Jie Chein ; Chi-Huey Wong ; Pan-Chyr Yang | JOURNAL OF MEDICINAL CHEMISTRY 63(6), 3172-3187 | |||
| 11 | 2020 | Disrupting the Conserved Salt Bridge in the Trimerization of Influenza A Nucleoprotein | Woodring, JL; Lu, SH; Krasnova, L; Wang, SC; Chen, JB; Chou, CC; Huang, YC; Cheng, TR ; Wu, YT; Chen, YH; Fang, JM; Tsai, MD; Wong, CH | Journal of medicinal chemistry 63(1), 205-215 | |||
| 12 | 2019 | Antibody blockade of Dectin-2 suppresses house dust mite-induced Th2 cytokine production in dendritic cell- and monocyte-depleted peripheral blood mononuclear cell co-cultures from asthma patients. | Chen, MH; Huang, MT; Yu, WK; Lee, SS; Wang, JH; Cheng, TR ; Bowman, MR; Hsieh, SL | JOURNAL OF BIOMEDICAL SCIENCE 26, 97 | |||
| 13 | 2019 | 4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin | Ming-Shiu Lin; Tse-Ming Hong; Ting-Hung Chou; Shuenn-Chen Yang; Wei-Chia Chung; Chia-Wei Weng; Mei-Ling Tsai; Ting-Jen Rachel Cheng ; Jeremy J. W. Chen; Te-Chang Lee ; Chi-Huey Wong ; Rong-Jie Chein ; Pan-Chyr Yang | European Journal of Medicinal Chemistry 181, 111584 | |||
| 14 | 2019 | Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer | Huang, MR; Hsu, YL; Lin, TC; Cheng, TJ ; Li, LW; Tseng, YW; Chou, YS; Liu, JH; Pan, SH; Fang, JM; Wong, CH | European journal of medicinal chemistry 181, 111551 | |||
| 15 | 2019 | Structural analysis and biological activity of cell wall polysaccharides extracted from Panax ginseng marc | Li, J; Wang, D; Xing, X; Cheng, TR ; Liang, PH; Bulone, V; Park, JH; Hsieh, YSY | International journal of biological macromolecules 135, 29-37 | |||
| 16 | 2019 | Boronate, trifluoroborate, sulfone, sulfinate and sulfonate congeners of oseltamivir carboxylic acid: Synthesis and anti-influenza activity | Hong, BT; Cheng, YE; Cheng, TJ ; Fang, JM | European journal of medicinal chemistry 163, 710-721 | |||
| 17 | 2019 | Development of a universal influenza vaccine using hemagglutinin stem protein produced from Pichia pastoris | S.-C. Wang; H.-Y. Liao; J.-Y. Zhang; T.-J. R. Cheng ; C.-H. Wong | VIROLOGY 526, 125-137 | |||
| 18 | 2018 | Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses | Hsu, PH; Chiu, DC; Wu, KL; Lee, PS; Jan, JT ; Cheng, YE; Tsai, KC; Cheng, TR ; Fang, JM | European journal of medicinal chemistry 154, 314-323 | |||
| 19 | 2018 | Development of Pseudomonas aeruginosa Lectin LecA Inhibitor by using Bivalent Galactosides Supported on Polyproline Peptide Scaffolds | Huang, SF; Lin, CH; Lai, YT; Tsai, CL; Cheng, TR ; Wang, SK | Chemistry, an Asian journal 13(6), 686-700 | |||
| 20 | 2018 | 2-anilino-4-amino-5-aroylthiazole-type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction | Hao-Wei Cheng; Rong-Jie Chein ; Ting-Jen Cheng ; Pei-Shan Wu; Hsin-Yi Wu; Pei-Fang Hung; Chia-Jen Wang; Yuan-Ling Hsu; Jau-Min Wong; Ang Yuan; Chi-Huey Wong ; Pan-Chyr Yang; Szu-Hua Pan | CANCER SCIENCE 109(3), 832-842 | |||
| 21 | 2017 | Peramivir analogues bearing hydrophilic side chains exhibit higher activities against H275Y mutant than wild-type influenza virus | Chiu, DC; Lin, TC; Huang, WI; Cheng, TJ ; Tsai, KC; Fang, JM | Organic & biomolecular chemistry 15(46), 9910-9922 | |||
| 22 | 2017 | Effect of the lipid II sugar moiety on bacterial transglycosylase: the 4-hydroxy epimer of lipid II is a TGase inhibitor | Chen, KT; Lin, CK; Guo, CW; Chang, YF; Hu, CM; Lin, HH; Lai, Y; Cheng, TR ; Cheng, WC | Chemical communications (Cambridge, England) 53(4), 771-774 | |||
| 23 | 2016 | Purine-Type Compounds Induce Microtubule Fragmentation and Lung Cancer Cell Death through Interaction with Katanin | Kuo, TC; Li, LW; Pan, SH; Fang, JM; Liu, JH; Cheng, TJ ; Wang, CJ; Hung, PF; Chen, HY ; Hong, TM; Hsu, YL; Wong, CH ; Yang, PC | Journal of medicinal chemistry 59(18), 8521-8534 |
