The power of genetic diversity in genome-wide association studies of lipids

Graham, SE; Clarke, SL; Wu, KH; Kanoni, S; Zajac, GJM; Ramdas, S; Surakka, I; Ntalla, I; Vedantam, S; Winkler, TW; Locke, AE; Marouli, E; Hwang, MY; Han, S; Narita, A; Choudhury, A; Bentley, AR; Ekoru, K; Verma, A; Trivedi, B; Martin, HC; Hunt, KA; Hui, Q; Klarin, D; Zhu, X; Thorleifsson, G; Helgadottir, A; Gudbjartsson, DF; Holm, H; Olafsson, I; Akiyama, M; Sakaue, S; Terao, C; Kanai, M; Zhou, W; Brumpton, BM; Rasheed, H; Ruotsalainen, SE; Havulinna, AS; Veturi, Y; Feng, Q; Rosenthal, EA; Lingren, T; Pacheco, JA; Pendergrass, SA; Haessler, J; Giulianini, F; Bradford, Y; Miller, JE; Campbell, A; Lin, K; Millwood, IY; Hindy, G; Rasheed, A; Faul, JD; Zhao, W; Weir, DR; Turman, C; Huang, H; Graff, M; Mahajan, A; Brown, MR; Zhang, W; Yu, K; Schmidt, EM; Pandit, A; Gustafsson, S; Yin, X; Luan, J; Zhao, JH; Matsuda, F; Jang, HM; Yoon, K; Medina-Gomez, C; Pitsillides, A; Hottenga, JJ; Willemsen, G; Wood, AR; Ji, Y; Gao, Z; Haworth, S; Mitchell, RE; Chai, JF; Aadahl, M; Yao, J; Manichaikul, A; Warren, HR; Ramirez, J; Bork-Jensen, J; Karhus, LL; Goel, A; Sabater-Lleal, M; Noordam, R; Sidore, C; Fiorillo, E; McDaid, AF; Marques-Vidal, P; Wielscher, M; Trompet, S; Sattar, N; Mollehave, LT; Thuesen, BH; Munz, M; Zeng, L; Huang, J; Yang, B; Poveda, A; Kurbasic, A; Lamina, C; Forer, L; Scholz, M; Galesloot, TE; Bradfield, JP; Daw, EW; Zmuda, JM; Mitchell, JS; Fuchsberger, C; Christensen, H; Brody, JA; Feitosa, MF; Wojczynski, MK; Preuss, M; Mangino, M; Christofidou, P; Verweij, N; Benjamins, JW; Engmann, J; Kember, RL; Slieker, RC; Lo, KS; Zilhao, NR; Le, P; Kleber, ME; Delgado, GE; Huo, S; Ikeda, DD; Iha, H; Yang, J; Liu, J; Leonard, HL; Marten, J; Schmidt, B; Arendt, M; Smyth, LJ; Canadas-Garre, M; Wang, C; Nakatochi, M; Wong, A; Hutri-Kahonen, N; Sim, X; Xia, R; Huerta-Chagoya, A; Fernandez-Lopez, JC; Lyssenko, V; Ahmed, M; Jackson, AU; Irvin, MR; Oldmeadow, C; Kim, HN; Ryu, S; Timmers, PRHJ; Arbeeva, L; Dorajoo, R; Lange, LA; Chai, X; Prasad, G; Lores-Motta, L; Pauper, M; Long, J; Li, X; Theusch, E; Takeuchi, F; Spracklen, CN; Loukola, A; Bollepalli, S; Warner, SC; Wang, YX; Wei, WB; Nutile, T; Ruggiero, D; Sung, YJ; Hung, YJ; Chen, S; Liu, F; Yang, J; Kentistou, KA; Gorski, M; Brumat, M; Meidtner, K; Bielak, LF; Smith, JA; Hebbar, P; Farmaki, AE; Hofer, E; Lin, M; Xue, C; Zhang, J; Concas, MP; Vaccargiu, S; van, der, Most, PJ; Pitkanen, N; Cade, BE; Lee, J; van, der, Laan, SW; Chitrala, KN; Weiss, S; Zimmermann, ME; Lee, JY; Choi, HS; Nethander, M; Freitag-Wolf, S; Southam, L; Rayner, NW; Wang, CA; Lin, SY; Wang, JS; Couture, C; Lyytikainen, LP; Nikus, K; Cuellar-Partida, G; Vestergaard, H; Hildalgo, B; Giannakopoulou, O; Cai, Q; Obura, MO; van, Setten, J; Li, X; Schwander, K; Terzikhan, N; Shin, JH; Jackson, RD; Reiner, AP; Martin, LW; Chen, Z; Li, L; Highland, HM; Young, KL; Kawaguchi, T; Thiery, J; Bis, JC; Nadkarni, GN; Launer, LJ; Li, H; Nalls, MA; Raitakari, OT; Ichihara, S; Wild, SH; Nelson, CP; Campbell, H; Jager, S; Nabika, T; Al-Mulla, F; Niinikoski, H; Braund, PS; Kolcic, I; Kovacs, P; Giardoglou, T; Katsuya, T; Bhatti, KF; de, Kleijn, D; de, Borst, GJ; Kim, EK; Adams, HHH; Ikram, MA; Zhu, X; Asselbergs, FW; Kraaijeveld, AO; Beulens, JWJ; Shu, XO; Rallidis, LS; Pedersen, O; Hansen, T; Mitchell, P; Hewitt, AW; Kahonen, M; Perusse, L; Bouchard, C; Tonjes, A; Chen, YI; Pennell, CE; Mori, TA; Lieb, W; Franke, A; Ohlsson, C; Mellstrom, D; Cho, YS; Lee, H; Yuan, JM; Koh, WP; Rhee, SY; Woo, JT; Heid, IM; Stark, KJ; Volzke, H; Homuth, G; Evans, MK; Zonderman, AB; Polasek, O; Pasterkamp, G; Hoefer, IE; Redline, S; Pahkala, K; Oldehinkel, AJ; Snieder, H; Biino, G; Schmidt, R; Schmidt, H; Chen, YE; Bandinelli, S; Dedoussis, G; Thanaraj, TA; Kardia, SLR; Kato, N; Schulze, MB; Girotto, G; Jung, B; Boger, CA; Joshi, PK; Bennett, DA; De, Jager, PL; Lu, X; Mamakou, V; Brown, M; Caulfield, MJ; Munroe, PB; Guo, X; Ciullo, M; Jonas, JB; Samani, NJ; Kaprio, J; Pajukanta, P; Adair, LS; Bechayda, SA; de, Silva, HJ; Wickremasinghe, AR; Krauss, RM; Wu, JY; Zheng, W; den, Hollander, AI; Bharadwaj, D; Correa, A; Wilson, JG; Lind, L; Heng, CK; Nelson, AE; Golightly, YM; Wilson, JF; Penninx, B; Kim, HL; Attia, J; Scott, RJ; Rao, DC; Arnett, DK; Walker, M; Koistinen, HA; Chandak, GR; Yajnik, CS; Mercader, JM; Tusie-Luna, T; Aguilar-Salinas, CA; Villalpando, CG; Orozco, L; Fornage, M; Tai, ES; van, Dam, RM; Lehtimaki, T; Chaturvedi, N; Yokota, M; Liu, J; Reilly, DF; McKnight, AJ; Kee, F; Jockel, KH; McCarthy, MI; Palmer, CNA; Vitart, V; Hayward, C; Simonsick, E; van, Duijn, CM; Lu, F; Qu, J; Hishigaki, H; Lin, X; Marz, W; Parra, EJ; Cruz, M; Gudnason, V; Tardif, JC; Lettre, G; Hart, LM't; Elders, PJM; Damrauer, SM; Kumari, M; Kivimaki, M; van, der, Harst, P; Spector, TD; Loos, RJF; Province, MA; Psaty, BM; Brandslund, I; Pramstaller, PP; Christensen, K; Ripatti, S; Widen, E; Hakonarson, H; Grant, SFA; Kiemeney, LALM; de, Graaf, J; Loeffler, M; Kronenberg, F; Gu, D; Erdmann, J; Schunkert, H; Franks, PW; Linneberg, A; Jukema, JW; Khera, AV; Mannikko, M; Jarvelin, MR; Kutalik, Z; Cucca, F; Mook-Kanamori, DO; van, Dijk, KW; Watkins, H; Strachan, DP; Grarup, N; Sever, P; Poulter, N; Rotter, JI; Dantoft, TM; Karpe, F; Neville, MJ; Timpson, NJ; Cheng, CY; Wong, TY; Khor, CC; Sabanayagam, C; Peters, A; Gieger, C; Hattersley, AT; Pedersen, NL; Magnusson, PKE; Boomsma, DI; de, Geus, EJC; Cupples, LA; van, Meurs, JBJ; Ghanbari, M; Gordon-Larsen, P; Huang, W; Kim, YJ; Tabara, Y; Wareham, NJ; Langenberg, C; Zeggini, E; Kuusisto, J; Laakso, M; Ingelsson, E; Abecasis, G; Chambers, JC; Kooner, JS; de, Vries, PS; Morrison, AC; North, KE; Daviglus, M; Kraft, P; Martin, NG; Whitfield, JB; Abbas, S; Saleheen, D; Walters, RG; Holmes, MV; Black, C; Smith, BH; Justice, AE; Baras, A; Buring, JE; Ridker, PM; Chasman, DI; Kooperberg, C; Wei, WQ; Jarvik, GP; Namjou, B; Hayes, MG; Ritchie, MD; Jousilahti, P; Salomaa, V; Hveem, K; Asvold, BO; Kubo, M; Kamatani, Y; Okada, Y; Murakami, Y; Thorsteinsdottir, U; Stefansson, K; Ho, YL; Lynch, JA; Rader, DJ; Tsao, PS; Chang, KM; Cho, K; O'Donnell, CJ; Gaziano, JM; Wilson, P; Rotimi, CN; Hazelhurst, S; Ramsay, M; Trembath, RC; van, Heel, DA; Tamiya, G; Yamamoto, M; Kim, BJ; Mohlke, KL; Frayling, TM; Hirschhorn, JN; Kathiresan, S; Boehnke, M; Natarajan, P; Peloso, GM; Brown, CD; Morris, AP; Assimes, TL; Deloukas, P; Sun, YV; Willer, CJ

Please use this identifier to cite or link to this item: http://ir.sinica.edu.tw/handle/201000000A/83338

Title:	The power of genetic diversity in genome-wide association studies of lipids
Authors:	Graham, SE Clarke, SL Wu, KH Kanoni, S Zajac, GJM Ramdas, S Surakka, I Ntalla, I Vedantam, S Winkler, TW Locke, AE Marouli, E Hwang, MY Han, S Narita, A Choudhury, A Bentley, AR Ekoru, K Verma, A Trivedi, B Martin, HC Hunt, KA Hui, Q Klarin, D Zhu, X Thorleifsson, G Helgadottir, A Gudbjartsson, DF Holm, H Olafsson, I Akiyama, M Sakaue, S Terao, C Kanai, M Zhou, W Brumpton, BM Rasheed, H Ruotsalainen, SE Havulinna, AS Veturi, Y Feng, Q Rosenthal, EA Lingren, T Pacheco, JA Pendergrass, SA Haessler, J Giulianini, F Bradford, Y Miller, JE Campbell, A Lin, K Millwood, IY Hindy, G Rasheed, A Faul, JD Zhao, W Weir, DR Turman, C Huang, H Graff, M Mahajan, A Brown, MR Zhang, W Yu, K Schmidt, EM Pandit, A Gustafsson, S Yin, X Luan, J Zhao, JH Matsuda, F Jang, HM Yoon, K Medina-Gomez, C Pitsillides, A Hottenga, JJ Willemsen, G Wood, AR Ji, Y Gao, Z Haworth, S Mitchell, RE Chai, JF Aadahl, M Yao, J Manichaikul, A Warren, HR Ramirez, J Bork-Jensen, J Karhus, LL Goel, A Sabater-Lleal, M Noordam, R Sidore, C Fiorillo, E McDaid, AF Marques-Vidal, P Wielscher, M Trompet, S Sattar, N Mollehave, LT Thuesen, BH Munz, M Zeng, L Huang, J Yang, B Poveda, A Kurbasic, A Lamina, C Forer, L Scholz, M Galesloot, TE Bradfield, JP Daw, EW Zmuda, JM Mitchell, JS Fuchsberger, C Christensen, H Brody, JA Feitosa, MF Wojczynski, MK Preuss, M Mangino, M Christofidou, P Verweij, N Benjamins, JW Engmann, J Kember, RL Slieker, RC Lo, KS Zilhao, NR Le, P Kleber, ME Delgado, GE Huo, S Ikeda, DD Iha, H Yang, J Liu, J Leonard, HL Marten, J Schmidt, B Arendt, M Smyth, LJ Canadas-Garre, M Wang, C Nakatochi, M Wong, A Hutri-Kahonen, N Sim, X Xia, R Huerta-Chagoya, A Fernandez-Lopez, JC Lyssenko, V Ahmed, M Jackson, AU Irvin, MR Oldmeadow, C Kim, HN Ryu, S Timmers, PRHJ Arbeeva, L Dorajoo, R Lange, LA Chai, X Prasad, G Lores-Motta, L Pauper, M Long, J Li, X Theusch, E Takeuchi, F Spracklen, CN Loukola, A Bollepalli, S Warner, SC Wang, YX Wei, WB Nutile, T Ruggiero, D Sung, YJ Hung, YJ Chen, S Liu, F Yang, J Kentistou, KA Gorski, M Brumat, M Meidtner, K Bielak, LF Smith, JA Hebbar, P Farmaki, AE Hofer, E Lin, M Xue, C Zhang, J Concas, MP Vaccargiu, S van, der, Most, PJ Pitkanen, N Cade, BE Lee, J van, der, Laan, SW Chitrala, KN Weiss, S Zimmermann, ME Lee, JY Choi, HS Nethander, M Freitag-Wolf, S Southam, L Rayner, NW Wang, CA Lin, SY Wang, JS Couture, C Lyytikainen, LP Nikus, K Cuellar-Partida, G Vestergaard, H Hildalgo, B Giannakopoulou, O Cai, Q Obura, MO van, Setten, J Li, X Schwander, K Terzikhan, N Shin, JH Jackson, RD Reiner, AP Martin, LW Chen, Z Li, L Highland, HM Young, KL Kawaguchi, T Thiery, J Bis, JC Nadkarni, GN Launer, LJ Li, H Nalls, MA Raitakari, OT Ichihara, S Wild, SH Nelson, CP Campbell, H Jager, S Nabika, T Al-Mulla, F Niinikoski, H Braund, PS Kolcic, I Kovacs, P Giardoglou, T Katsuya, T Bhatti, KF de, Kleijn, D de, Borst, GJ Kim, EK Adams, HHH Ikram, MA Zhu, X Asselbergs, FW Kraaijeveld, AO Beulens, JWJ Shu, XO Rallidis, LS Pedersen, O Hansen, T Mitchell, P Hewitt, AW Kahonen, M Perusse, L Bouchard, C Tonjes, A Chen, YI Pennell, CE Mori, TA Lieb, W Franke, A Ohlsson, C Mellstrom, D Cho, YS Lee, H Yuan, JM Koh, WP Rhee, SY Woo, JT Heid, IM Stark, KJ Volzke, H Homuth, G Evans, MK Zonderman, AB Polasek, O Pasterkamp, G Hoefer, IE Redline, S Pahkala, K Oldehinkel, AJ Snieder, H Biino, G Schmidt, R Schmidt, H Chen, YE Bandinelli, S Dedoussis, G Thanaraj, TA Kardia, SLR Kato, N Schulze, MB Girotto, G Jung, B Boger, CA Joshi, PK Bennett, DA De, Jager, PL Lu, X Mamakou, V Brown, M Caulfield, MJ Munroe, PB Guo, X Ciullo, M Jonas, JB Samani, NJ Kaprio, J Pajukanta, P Adair, LS Bechayda, SA de, Silva, HJ Wickremasinghe, AR Krauss, RM Wu, JY Zheng, W den, Hollander, AI Bharadwaj, D Correa, A Wilson, JG Lind, L Heng, CK Nelson, AE Golightly, YM Wilson, JF Penninx, B Kim, HL Attia, J Scott, RJ Rao, DC Arnett, DK Walker, M Koistinen, HA Chandak, GR Yajnik, CS Mercader, JM Tusie-Luna, T Aguilar-Salinas, CA Villalpando, CG Orozco, L Fornage, M Tai, ES van, Dam, RM Lehtimaki, T Chaturvedi, N Yokota, M Liu, J Reilly, DF McKnight, AJ Kee, F Jockel, KH McCarthy, MI Palmer, CNA Vitart, V Hayward, C Simonsick, E van, Duijn, CM Lu, F Qu, J Hishigaki, H Lin, X Marz, W Parra, EJ Cruz, M Gudnason, V Tardif, JC Lettre, G Hart, LM't Elders, PJM Damrauer, SM Kumari, M Kivimaki, M van, der, Harst, P Spector, TD Loos, RJF Province, MA Psaty, BM Brandslund, I Pramstaller, PP Christensen, K Ripatti, S Widen, E Hakonarson, H Grant, SFA Kiemeney, LALM de, Graaf, J Loeffler, M Kronenberg, F Gu, D Erdmann, J Schunkert, H Franks, PW Linneberg, A Jukema, JW Khera, AV Mannikko, M Jarvelin, MR Kutalik, Z Cucca, F Mook-Kanamori, DO van, Dijk, KW Watkins, H Strachan, DP Grarup, N Sever, P Poulter, N Rotter, JI Dantoft, TM Karpe, F Neville, MJ Timpson, NJ Cheng, CY Wong, TY Khor, CC Sabanayagam, C Peters, A Gieger, C Hattersley, AT Pedersen, NL Magnusson, PKE Boomsma, DI de, Geus, EJC Cupples, LA van, Meurs, JBJ Ghanbari, M Gordon-Larsen, P Huang, W Kim, YJ Tabara, Y Wareham, NJ Langenberg, C Zeggini, E Kuusisto, J Laakso, M Ingelsson, E Abecasis, G Chambers, JC Kooner, JS de, Vries, PS Morrison, AC North, KE Daviglus, M Kraft, P Martin, NG Whitfield, JB Abbas, S Saleheen, D Walters, RG Holmes, MV Black, C Smith, BH Justice, AE Baras, A Buring, JE Ridker, PM Chasman, DI Kooperberg, C Wei, WQ Jarvik, GP Namjou, B Hayes, MG Ritchie, MD Jousilahti, P Salomaa, V Hveem, K Asvold, BO Kubo, M Kamatani, Y Okada, Y Murakami, Y Thorsteinsdottir, U Stefansson, K Ho, YL Lynch, JA Rader, DJ Tsao, PS Chang, KM Cho, K O'Donnell, CJ Gaziano, JM Wilson, P Rotimi, CN Hazelhurst, S Ramsay, M Trembath, RC van, Heel, DA Tamiya, G Yamamoto, M Kim, BJ Mohlke, KL Frayling, TM Hirschhorn, JN Kathiresan, S Boehnke, M Natarajan, P Peloso, GM Brown, CD Morris, AP Assimes, TL Deloukas, P Sun, YV Willer, CJ
Issue Date:	2021
Relation:	Nature 600(7890), 675-679
URI:	http://ir.sinica.edu.tw/handle/201000000A/83338
ISSN:	http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Drexel&SrcApp=hagerty_opac&KeyRecord=0028-0836&DestApp=JCR&RQ=IF_CAT_BOXPLOT
URL:	http://dx.doi.org/10.1038/s41586-021-04064-3
Appears in Collections:	生物醫學科學研究所

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