Publications

Results 1-59 of 59 (Search time: 0.002 seconds).

Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
12023Development of AAV-delivered broadly neutralizing anti-human ACE2 antibodies against SARS-CoV-2 variantsSun, CP ; Chiu, CW; Wu, PY; Tsung, SI; Lee, IJ; Hu, CW; Hsu, MF; Kuo, TJ; Lan, YH; Chen, LY; Ng, HY; Chung, MJ; Liao, HN; Tseng, SC; Lo, CH; Chen, YJ; Liao, CC ; Chang, CS; Liang, JJ; Draczkowski, P; Puri, S; Chang, YC ; Huang, JS; Chen, CC; Kau, JH; Chen, YH ; Liu, WC ; Wu, HC ; Hsu, STD ; Wang, IH ; Tao, MH Molecular Therapy 31(11), 3322-3336
22023mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applicationsWang, Y. S.; Kumari, M.; Chen, G. H.; Hong, M. H.; Yuan, P. T.; Tsai, J. L.; Wu, H. C. Journal of Biomedical Science 30, 84
32023Epithelial cell adhesion molecule (EpCAM) regulates HGFR signaling to promote colon cancer progression and metastasisLee, C. C.; Yu, C. J.; Panda, S. S.; Chen, K. C.; Liang, K. H.; Huang, W.C. ; Wang, Y. S.; Ho, P. C.; Wu, H. C. Journal of Translational Medicine 21, 530
42023Broadly neutralizing human antibodies against Omicron subvariants of SARS-CoV-2Chiang, H. L.; Liang, K. L.; Lu, R. M. ; Kuo, T. W.; Lin, Y. L. ; Wu, H. C. Journal of Biomedical Science 30, 59
52023Bivalent mRNA Vaccine Effectiveness against SARS-CoV-2 Variants of ConcernKumari, M.; Su, S. C.; Liang, K. H.; Lin, H. T.; Lu, Y. F.; Chen, K. C.; Chen, W. Y.; Wu, H. C. Journal of Biomedical Science 30, 46
62023Broadly neutralizing antibodies against Omicron variants of SARS-CoV-2 derived from mRNA-lipid nanoparticle-immunized miceRuei-Min Lu ; Kang-Hao Liang; Hsiao-Ling Chiang; Fu-Fei Hs; Hsiu-Ting Lin; Wan-Yu Chen; Feng-Yi Ke; Monika Kumari; Yu-Chi Chou ; Mi-Hua Tao ; Yi-Ling Lin ; Han-Chung Wu Heliyon 9(5), e15587
72023SARS-CoV-2 N protein mediates intercellular nucleic acid dispersion, a feature reduced in OmicronWu, Jung-Lin; Kuan, I.-I.; Guo, Jing-You; Hsu, Wei-Chia; Tang, Wei-Chun; Chan, Hsin-Ju; Chen, Yu-Ju ; Chen, Bi-Chang ; Wu, Han-Chung ; Liao, James C.iScience 26(2), 105995
82023Study on antibody Fc-glycosylation for optimal effector functionsV.-S. Shivatare; P.-K. Chuang; T.-H. Tseng; Y.-F. Zeng; H.-W. Huang; G. Veeranjaneyulu; H.-C. Wu ; C.-H. Wong Chemical communications (Cambridge, England) 59(37), 5555-5558
92022Monoclonal antibodies against S2 subunit of spike protein exhibit broad reactivity toward SARS-CoV-2 variantsKo, S. H.; Chen, W. Y.; Su, S. C.; Lin, H. T.; Ke, F. Y.; Liang, K. H.; Hsu, F. F.; Kumari, M.; Fu, V. Y.; Wu, H. C. Journal of Biomedical Science 29, 108
102022Podocalyxin-Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis PathwayChen, Wei‐Ju; Huang, Wei‐Kai; Pather, Sarshan R.; Chang, Wei‐Fang; Sung, Li‐Ying; Wu, Han‐Chung ; Liao, Mei‐Ying; Lee, Chi‐Chiu; Wu, Hsuan‐Hui; Wu, Chung‐Yi ; Liao, Kuo‐Shiang; Lin, Chun‐Yu; Yang, Shang‐Chih; Lin, Hsuan; Lai, Pei‐Lun; Ng, Chi‐Hou; Hu, Chun‐Mei ; Chen, I‐Chih; Chuang, Chi‐Hsuan; Lai, Chien‐Ying; Lin, Po‐Yu; Lee, Yueh‐Chang; Schuyler, Scott C.; Schambach, Axel; Lu, Frank Leigh; Lu, Jean Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10(1), e2205451
112022An efficient approach for SARS-CoV-2 monoclonal antibody production via modified mRNA-LNP immunizationHsu, FF; Liang, KH; Kumari, M; Chen, WY; Lin, HT; Cheng, CM; Tao, MH ; Wu, HC International Journal of Pharmaceutics 627:122256, 1-10
122022Collagen-binding peptides for the enhanced imaging, lubrication and regeneration of osteoarthritic articular cartilageChin-Yu Lin; Yung-Li Wang; Yu-Jen Chen; Chun-Te Ho; Yi-Hsuan Chi; Long Yi Chan; Guan-Wen Chen; Horng-Chaung Hsu; Dennis W. Hwang ; Han-Chung Wu ; Shih-Chieh HungNature Biomedical Engineering 6, 1105-1117
132022Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturationLee, Wen-Hsin; Chen, Xiaorui; Liu, I-Ju; Lee, Jiin-Horng; Hu, Chun-Mei ; Wu, Han-Chung ; Wang, Sheng-Kai; Lee, Wen-Hwa ; Ma, Che Cell Reports 41(4), 111555
142022A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodiesKumari, Monika; Lu, Ruei-Min ; Li, Mu-Chun; Huang, Jhih-Liang; Hsu, Fu-Fei; Ko, Shih-Han; Ke, Feng-Yi; Su, Shih-Chieh; Liang, Kang-Hao; Yuan, Joyce Pei-Yi; Chiang, Hsiao-Ling; Sun, Cheng-Pu; Lee, I.-Jung; Li, Wen-Shan ; Hsieh, Hsing-Pang ; Tao, Mi-Hua ; Wu, Han-Chung Journal of Biomedical Science 29(1), 68
152022A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variantsLee, I-Jung; Sun, Cheng-Pu ; Wu, Ping-Yi; Lan, Yu-Hua; Wang, I-Hsuan ; Liu, Wen-Chun ; Yuan, Joyce, Pei-Yi; Chang, Yu-Wei; Tseng, Sheng-Che; Tsung, Szu-I; Chou, Yu-Chi ; Kumari, Monika; Lin, Yin-Shiou; Chen, Hui-Feng; Chen, Tsung-Yen; Lin, Chih-Chao; Chiu, Chi-Wen; Hsieh, Chung-Hsuan; Chuang, Cheng-Ying; Cheng, Chao-Min; Lin, Hsiu-Ting; Chen, Wan-Yu; Hsu, Fu-Fei; Hong, Ming-Hsiang; Liao, Chun-Che ; Chang, Chih-Shin; Liang, Jian-Jong; Ma, Hsiu-Hua; Chiang, Ming-Tsai; Liao, Hsin-Ni; Ko, Hui-Ying; Chen, Liang-Yu; Ko, Yi-An; Yu, Pei-Yu; Yang, Tzu-Jing; Chiang, Po-Cheng; Hsu, Shang-Te ; Lin, Yi-Ling ; Lee, Chong-Chou; Wu, Han-Chung ; Tao, Mi-Hua Journal of Biomedical Science 29(1), 49
162022Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detectionYu-Chyi Hwang; Ruei-Min Lu ; Shih-Chieh Su; Pao-Yin Chiang; Shih-Han Ko; Feng-Yi Ke; Kang-Hao Liang; Tzung-Yang Hsieh; Han-Chung Wu Journal of Biomedical Science 29, 1
172022Omicron-specific mRNA vaccine induced potent neutralizing antibody against Omicron but not other SARS-CoV-2 variantsLee, IJ; Sun, CP; Wu, PY; Lan, YH; Wang, IH ; Liu, WC ; Tseng, SC; Tsung, SI; Chou, YC ; Kumari, M; Chang, YW; Chen, HF; Lin, YS; Chen, TY; Chiu, CW; Hsieh, CH; Chuang, CY; Lin, CC; Cheng, CM; Lin, HT; Chen, WY; Chiang, PC; Lee, CC; Liao, JC; Wu, HC ; Tao, MH BioRxiv
182022Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumoursHuang, H. C.; Sung, Y. C.; Li, C. P.; Wan, D.; Chao, P. H.; Liao, B. W.; Cheng, H. T.; Hsu, F. F.; Huang, C. C.; Liao, Y. H.; Hsieh, H. T.; Shih, Y. C.; Liu, I. J.; Wu, H. C. ; Lu, T. T.; Wang, J.; Chen, Y.Gut 71, 1843-1855
192022Functionalized osteoarthritis targeting peptides for MRI, lubricant and regenerative medicineLin, C. Y.; Wang, Y. L.; Chi, Y. H.; Chan, L. Y.; Ho, C. T.; Chen, G. W.; Hsu, H. C.; Hwang, D. W. ; Wu, H. C. ; Hung, S. C.Nature Biomedical Engineering
202021Homogeneous antibody and CAR-T cells with improved effector functions targeting SSEA-4 glycan on pancreatic cancerLin, Chih-Wei; Wang, Yu-Jen; Lai, Ting-Yen; Hsu, Tsui-Ling ; Han, Shin-Ying; Wu, Han-Chung ; Shen, Chia-Ning ; Dang, Van; Chen, Ming-Wei; Chen, Lan-Bo; Wong, Chi-Huey Proceedings of The National Academy of Sciences of the United States of America 118(50), e2114774118
212021Antibody cocktail effective against variants of SARS-CoV-2Liang, Kang-Hao; Chiang, Pao-Yin; Ko, Shih-Han; Chou, Yu-Chi ; Lu, Ruei-Min ; Lin, Hsiu-Ting; Chen, Wan-Yu; Lin, Yi-Ling ; Tao, Mi-Hua ; Jan, Jia-Tsrong ; Wu, Han-Chung Journal of biomedical science 28, 80
222021Monoclonal antibodies against nucleocapsid protein of SARS-CoV-2 variants for detection of COVID-19Lu, R. M. ; Ko, S. H.; Chen, W. Y.; Chang, U. L.; Lin, H. T.; Wu, H. C. International Journal of Molecular Sciences 22(22), 12412
232021Structure-guided Antibody Cocktail for Prevention and Treatment of COVID-19Shih-Chieh Su; Tzu-Jing Yang; Pei-Yu Yu; Kang-Hao Liang; Wan-Yu Chen; Chun-Wei Yang; Hsiu-Ting Lin; Meng-Jhe Wang; Ruei-Min Lu ; Hsien-Cheng Tso; Meng-Jhe Chung; Tzung-Yang Hsieh; Yu-Ling Chang; Shin-Chang Lin; Fang-Yu Hsu; Feng-Yi Ke; Yi-Hsuan Wu; Yu-Chyi Hwang; I-Ju Liu; Jian-Jong Liang; Chun-Che Liao ; Hui-Ying Ko; Cheng-Pu Sun ; Ping-Yi Wu; Jia-Tsrong Jan ; Yuan-Chih Chang ; Yi-Ling Lin ; Mi-Hua Tao ; Shang-Te Danny Hsu ; Han-Chung Wu PLOS Pathogens 17(10), e1009704
242021Structure-activity relationships of B.1.617 and other SARS-CoV-2 spike variantsTzu-Jing Yang; Pei-Yu Yu; Yuan-Chih Chang ; Ning-En Chang; Yu-Xi Tsai; Kang-Hao Liang; Piotr Draczkowski; Bertina Lin; Yong-Sheng Wang; Yu-Chun Chien; Kay-Hooi Khoo ; Han-Chung Wu ; Shang-Te Danny Hsu bioRxiv
252021Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and functionYang, TJ; Yu, PY; Chang, YC ; Liang, KH; Tso, HC; Ho, MR ; Chen, WY; Lin, HT; Wu, HC ; Hsu, STD NATURE STRUCTURAL & MOLECULAR BIOLOGY 28, 731-739
262021Rapid generation of mouse model for emerging infectious disease with the case of severe COVID-19Sun, Cheng-Pu ; Jan, Jia-Tsrong ; Wang, I-Hsuan ; Ma, Hsiu-Hua; Ko, Hui-Ying; Wu, Ping-Yi; Kuo, Tzu-Jiun; Liao, Hsin-Ni; Lan, Yu-Hua; Sie, Zong-Lin; Chen, Yen-Hui ; Ko, Yi-An; Liao, Chun-Che ; Chen, Liang-Yu; Lee, I-Jung; Tsung, Szu-I; Lai, Yun-Ju; Chiang, Ming-Tsai; Liang, Jian-Jong; Liu, Wen-Chun ; Wang, Jing-Rong; Yuan, Joyce Pei-Yi; Lin, Yin-Shiou; Tsai, Yi-Ching; Hsieh, Shie-Liang ; Li, Chia-Wei ; Wu, Han-Chung ; Ko, Tai-Ming; Lin, Yi-Ling ; Tao, Mi-Hua PLoS pathogens 17(8), e1009758
272021ENO1 Promotes Lung Cancer Metastasis via HGFR and WNT Signaling-Driven Epithelial-to-Mesenchymal TransitionLi, H. J.; Ke, F. Y.; Lin, C.C.; Lu, M. Y.; Kuo, Y. H.; Wang, Y. P.; Lin, S. C.; Chang, Y. H.; Chen, H. Y. ; Yang, P. C. ; Wu, H. C. Cancer research 81(15), 4094-4109
282021NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neckWang, Y. P.; Liu, I. J.; Chen, K. C.; Wu, H. C. Oncogenesis 10, 59
292021Identification of COVID-19 B-cell epitopes with phage-displayed peptide libraryGuo, J. Y.; Liu, I. J.; Lin, H. T.; Wang, M. J.; Chang, Y. L.; Lin, S. C.; Liao, M. Y.; Hsu, W. C.; Lin, Y. L. ; Liao, J. C.; Wu, H. C. Journal of Biomedical Science 28, 43
302021Combined Effect of Anti-SSEA4 and Anti-Globo H Antibodies on Breast Cancer CellsR.-H. Lee; Y.-J. Wang; T.-Y. La; T.-L. Hsu ; P.-K. Chuang; H.-C. Wu ; C.-H. Wong ACS chemical biology 16(8), 1526-1537
312020EpCAM signaling promotes tumor progression and protein stability of PD-L1 through EGFR pathwayChen, H. N.; Liang, K. H.; Lai, J. K.; Lan, C. H.; Liao, M. Y.; Hung, S. H.; Chuang, Y. T.; Chen, K. C.; Tsuei, W. W. F.; Wu, H. C. Cancer Research 80(22), 5035-5050
322020Potent neutralizing antibody cocktail for prevention and treatment of COVID-19.Wu, H. C. 
332020Novel monoclonal antibody against integrin α3 shows therapeutic potential for ovarian cancerKe, F. Y.; Chen, W. Y.; Lin, M. C.; Hwang, Y. C.; Kuo, K. T.; Wu, H. C. Cancer Science 111(10), 3478-3492
342020Novel SARS-CoV-2-Neutralizing antibodies for prevention and treatment of COVID-19Wu, H. C. 
352020Novel anti-EGFR scFv human antibody-conjugated immunoliposomes enhance chemotherapeutic efficacy in squamous cell carcinoma of head and neckWang, Y. P.; Liu, I. J.; Chung, M. J.; Wu, H. C. Oral Oncology 106, 104689
362020Imaging and biodistribution of radiolabeled SP90 peptide in BT-483 tumor bearing miceLo, WL; Liang, CH; Chen, LC; Lee, SY; Lo, SN; Chen, MW; Lu, RM ; Liu, IJ; Wu, HC ; Chang, CHApplied Radiation and Isotopes 161, 109162
372020Development of therapeutic antibodies for the treatment of diseasesRuei-Min Lu ; Yu-Chyi Hwang; I-Ju Liu; Chi-Chiu Lee; Han-Zen Tsai; Hsin-Jung Li; Han-Chung Wu Journal of Biomedical Science 27, 1
382020CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R PathwayCheng, Chih-Lun; Yang, Shang-Chih; Lai, Chien-Ying; Wang, Cheng-Kai; Chang, Ching-Fang; Lin, Chun-Yu; Chen, Wei-Ju; Lin, Po-Yu; Wu, Han-Chung ; Ma, Nianhan; Lu, Frank Leigh; Lu, Jean Cells 9(7), 1706
392020Peptide Targeting MethodsLu, Ruei-Min ; Wu, Chien-Hsun; Patil Ajay V.; Wu, Han-Chung Handbook of In Vivo Chemistry in Mice: From Lab to Living System (USA : Wiley-VCH)
402019Novel human Ab against vascular endothelial growth factor receptor 2 shows therapeutic potential for leukemia and prostate cancerLu, R. M. ; Chiu, C. Y.; Liu, I. J.; Chang, Y. L.; Liu, Y. J.; Wu, H. C. Cancer Science 110(12), 3773-3787
412019Antibody-based therapeutics for cancer theranosticsWu, H. C. 
422019PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerizationLi, MY; Peng, WH; Wu, CH; Chang, YM; Lin, YL; Chang, GD; Wu, HC ; Chen, GC ONCOGENE 38(44), 7002-7016
432019Development of antibody-based theranostics for treatment of cancerWu, H. C. 
442019Dengue and Zika virus domain III-flagellin fusion and glycan- masking E antigen for prime-boost immunization.Lin, H. H.; Yang, S. P.; Tsai, M. J.; Lin, G. C.; Wu, H. C. ; Wu, S. C.Theranostics 9(16), 4811-4826
452019Development of Targeting Nanoparticles for Cancer Molecular Imaging and TherapyWu. H.C. 
462019The extracellular domain of epithelial cell adhesion molecule (EpCAM) enhances multipotency of mesenchymal stem cells through EGFR-LIN28-LET7 signalingKuan, I. I.; Chen, C. H.; Lu, J. ; Wu, H. C. The Journal of Biological Chemistry 294(19), 7769-7786
472019Liposomal irinotecan for treatment of colorectal cancer in a preclinical model.Huang, J. R.; Lee, M. H.; Li, W. S. ; Wu, H. C. Cancers (Basel) 11(3), 281
482019Spectroscopic Micro Imaging Ellipsometry for Studying Effects of Drug Treatment in Colon Cancer CellsY-D Chen; C-H Wu; H. Y. Hsu; M. I. Khaleel; Y-C. Chang ; H-C. Wu International Journal of Precious Engineering Research and Applications 4(1), 9-22
492018Liposomal Paclitaxel Induces Fewer Hematopoietic and Cardiovascular Complications than Bioequivalent Doses of TaxolShih-Ting Huang; Yi‑Ping Wang; Yen-Hui Chen ; Chin-Tarng Lin; Wen-Shan Li ; Han-Chung Wu International Journal of Oncology 53(3), 1105-1117
502017Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ.Lee, W. Y.; Chen, P. C.; Wu, W. S.; Wu, H. C. ; Lan, C. H.; Huang, Y. H.; Cheng, C. H.; Chen, K. C.; Lin, C. W.International Journal of Cancer 141(9), 1921-1931
512016Advancement and applications of peptide phage display technology in biomedical scienceWu, CH; Liu, IJ; Lu, RM ; Wu, HC Journal of biomedical science 23(1), 8
522016Nature-inspired design of tetraindoles: Optimization of the core structure and evaluation of structure–activity relationshipAbdu-Allah, HH; Huang, ST; Chang, TT; Chen, CL; Wu, HC ; Li, WS Bioorganic & medicinal chemistry letters 26(18), 4497-4503
532015An anti-EpCAM antibody EpAb2-6 for the treatment of colon cancerLiao, M. Y.; Lai, J. K.; Kuo, M. Y. P.; Lu, R. ; Lin, C. W.; Cheng, P. C.; Liang, K. H.; Wu, H. C. Oncotarget 6(28), 24947-24968
542013Peptide-mediated liposomal Doxorubicin enhances drug delivery efficiency and therapeutic efficacy in animal modelsChang, DK; Li, PC; Lu, Ruei-Min ; Jane, WN ; Wu, HC PLOS ONE 8(12), e83239
552013Targeted drug delivery systems mediated by a novel Peptide in breast cancer therapy and imagingLu, Ruei-Min ; Chen, MS; Chang, DK; Chiu, CY; Lin, WC; Yan, SL; Wang, YP; Kuo, YS; Yeh, CY; Lo, A; Wu, HC PLOS ONE 8(6), e66128
562012Nucleolin antisense oligodeoxynucleotides induce apoptosis and may be used as a potential drug for nasopharyngeal carcinoma therapyWu, CD; Chou, HW; Kuo, YS; Lu, RM ; Hwang, YC; Wu, HC ; Lin, CTOncology Reports 27, 94-100
572011Surface marker epithelial cell adhesion molecule and E-cadherin facilitate the identification and selection of induced pluripotent stem cellsChen, HF; Chuang, CY; Lee, WC; Huang, HP; Wu, HC ; Ho, HN; Chen, YJ ; Kuo, HC STEM CELL REVIEWS 7(3), 722-735
582011Single chain anti-c-Met antibody conjugated nanoparticles for in vivo tumor-targeted imaging and drug deliveryLu, Ruei-Min ; Chang, Yu-Ling; Chen, Min-Shan; Wu, Han-Chung Biomaterials 32(12), 3265-3274
592010Epithelial Cell Adhesion Molecule Regulation Is Associated with the Maintenance of the Undifferentiated Phenotype of Human Embryonic Stem CellsLu, Tung-Ying; Lu, Ruei-Min ; Liao, Mei-Ying; Yu, John ; Chung, Chu-Hung; Kao, Cheng-Fu ; Wu, Han-Chung Journal of Biological Chemistry 285(12), 8719-8732