研究成果

第 1 到 10 筆結果，共 10 筆。

公開日期題名作者關聯scopusWOS全文
12023Discovery of small-molecule protein stabilizers toward exogenous alpha-l-iduronidase to reduce the accumulated heparan sulfate in mucopolysaccharidosis type I cellsLin, Hung-Yi; Chang, Shih-Ying; Teng, Hsuan-Hsuan; Wu, Hsi-Ju; Li, Huang-Yi; Cheng, Chia-Chun; Chuang, Chih-Kuang; Lin, Hsiang-Yu; Lin, Shuan-Pei; Cheng, Wei-Chieh European Journal of Medicinal Chemistry 247, 115005
22023Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe diseaseLi, Huang-Yi; Lee, Ni-Chung; Chiu, Yu-Ting; Chang, Yu-Wen; Lin, Chu-Chung; Chou, Cheng-Li; Chien, Yin-Hsiu; Hwu, Wuh-Liang; Cheng, Wei-Chieh BIOORGANIC & MEDICINAL CHEMISTRY 78, 117129
32022Combating multidrug-resistant Helicobacter pylori with moenomycin A in combination with clarithromycin or metronidazoleTseng, Yen-Yu; Liou, Jyh-Ming; Cheng, Wei-Chieh ; Hsu, Jing-Ting; Hsu, Tsui-Ling ; Wu, Ming-Shiang; Wong, Chi-Huey Frontiers in Chemistry 10, 897578
42022Harnessing natural-product-inspired combinatorial chemistry and computation-guided synthesis to develop N-glycan modulators as anticancer agentsChen, Wei-An; Chen, Yu-Hsin; Hsieh, Chiao-Yun; Hung, Pi-Fang; Chen, Chiao-Wen; Chen, Chien-Hung; Lin, Jung-Lee ; Cheng, Ting-Jen R. ; Hsu, Tsui-Ling ; Wu, Ying-Ta ; Shen, Chia-Ning ; Cheng, Wei-Chieh Chemical Science 13(21), 6233-6243
52022Synthesis of Nitrone-derived Pyrrolidine Scaffolds and Their Combinatorial Libraries to Develop Selective α-l-Rhamnosidase InhibitorsChen, WA; Li, HY; Sayyad, A; Huang, CY; Cheng, WC Chemistry, an Asian journal 17(14), e202200172
62021Harnessing fluorescent moenomycin A antibiotics for bacterial cell wall imaging studiesHsieh, PY; Meng, FC; Guo, CW; Hu, KH; Shih, YL ; Cheng, WC CHEMBIOCHEM 22(24), 3462-3468
72020Rapid Synthesis of a Natural Product-Inspired Uridine Containing LibraryCheng, WC ; Liu, WJ; Hu, KH; Tan, YL; Lin, YT; Chen, WA; Lo, LCACS combinatorial science 22(11), 600-607
82020Further Insights on Structural Modifications of Muramyl Dipeptides to Study the Human NOD2 Stimulating ActivityCheng, Wei-Chieh ; You, Ting-Yun; Teo, Zhen-Zhuo; Sayyad, Ashik A.; Maharana, Jitendra; Guo, Chih-Wei; Liang, Pi-Hui; Lin, Chung-Shun; Meng, Fan-ChunChemistry – An Asian Journal 15(22), 3836-3844
92019Divergent Synthesis of Bicyclic Iminosugars: Preparation of (−)-Swainsonine-Based Alkaloids and Their Inhibition Study towards α-Human MannosidasesChen, Wei-An; Sayyad, Ashik; Chen, Chiao-Wen; Chen, Yu-Hsin; Cheng, Ting-Jen R.; Cheng, Wei-Chieh Asian Journal of Organic Chemistry 8(12), 2233-2242
102012Identification of a small-molecule inhibitor of dengue virus using a replicon systemHsu, Y. C.; Chen, N. C.; Chen, P. J.; Wang, C. C.; Cheng, W. C. ; Wu, H. N. Archives of virology 157(4), 681-688