Publications

Results 1-19 of 19 (Search time: 0.004 seconds).

Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
12024Sulfated disaccharide protects membrane and DNA damages from arginine-rich dipeptide repeats in ALSYu-Jen Chang; Kai-Tai Lin; Orion Shih; Chi-Hua Yang; Ching-Yu Chuang; Ming-Han Fang; Wei-Bin Lai; Yi-Chung Lee; Hung-Chih Kuo ; Shang-Cheng Hung ; Chi-Kuang Yao ; U-Ser Jeng; Yun-Ru Chen SCIENCE ADVANCES 10(8), eadj0347
22024Detection of Femtomolar Amyloid-β Peptides for Early-Stage Identification of Alzheimer’s Amyloid-β Aggregation with Functionalized Gold NanoparticlesChang, Yu-Jen; Chien, Yi-Hsin; Chang, Chieh-Chun; Wang, Pei-Ning; Chen, Yun-Ru ; Chang, Yun-Chorng ACS Applied Materials & Interfaces 16(3), 3819-3828
32024Amyloid Modifier SERF1a Accelerates Alzheimer’s Amyloid-β Fibrillization and Exacerbates the CytotoxicityTien-Ying Tsai; Wei-Ting Jhang; Hung-Kai Hsu; Yi-Tsu Chan; Chi-Fon Chang ; Yun-Ru Chen ACS Chemical Neuroscience 15(3), 479-490
42024Sequential rearrangement and stereochemical reorganization to design an antimicrobial peptide with enhanced stabilityHsu, Po-Hsien; Hazam, Prakash Kishore; Huang, Yi-Ping; Yeh, Jih-Chao; Chen, Yun-Ru ; Li, Chao-Chin ; Chang, Chi-Fon ; Liou, Je-Wen; Chen, Jyh-Yih Biomedicine & Pharmacotherapy 170, 116088
52023Optimization of sequence and chiral content enhances therapeutic potential of tilapia piscidin peptidesHsu, Po-Hsien; Hazam, Prakash, Kishore; Huang, Yi-Ping; Yeh, Jih-Chao; Chen, Yun-Ru ; Li, Chao-Chin ; Chang, Chi-Fon ; Liou, Je-Wen; Chen, Jyh-Yih European Journal of Medicinal Chemistry 265, 116083-Online ahead of prin
62023Amyloid Modifier SERF1a Interacts with PolyQ-expanded Huntingtin-Exon 1 via Helical Interactions and Exacerbates PolyQ-induced ToxicityTien-Ying Tsai§; Chun-Yu Chen§; Tien-Wei Lin; Tien-Chang Lin; Feng-Lan Chiu; Orion Shih; Ming-Yun Chang; Yu-Chun Lin; An-Chung Su; U-Ser Jeng; Hung-Chih Kuo ; Chi-Fon Chang ; Yun-Ru Chen Communications Biology 6, 767
72023Ganglioside-focused Glycan Array Reveals Abnormal Anti-GD1b Auto-antibody in Plasma of Preclinical Huntington’s DiseaseTien-Wei Lin; Jung-Kai Chang; Yih-Ru Wu; Tsung-Hsien Sun; Yang-Yu Cheng; Chien-Tai Ren ; Mei-Hung Pan; Jin-Lin Wu; Kuo-Hsuan Chang; Hwai-I Yang ; Chiung-Mei Chen; Chung-Yi Wu ; Yun-Ru Chen MOLECULAR NEUROBIOLOGY 60, 3873-3882
82023Rational Design of Stapled Antimicrobial Peptides to Enhance Stability and In Vivo Potency against Polymicrobial SepsisYeh, Jih-Chao; Hazam, Prakash Kishore; Hsieh, Chu-Yi; Hsu, Po-Hsien; Lin, Wen-Chun; Chen, Yun-Ru ; Li, Chao-Chin ; Chen, Jyh-Yih Microbiology Spectrum 11(2), e0385322
92022Signal peptide stabilizes folding and inhibits misfolding of serum amyloid AJin-Lin Wu; Yun-Ru Chen PROTEIN SCIENCE 31(12), e4485
102022Nickel superoxide dismutase protects nitrogen fixation in TrichodesmiumChen, C.-C.; I. B. Rodriguez; Y.-l. L. Chen; J. P. Zehr; Y.-R. Chen ; S.-T. D. Hsu ; S.-C. Yang; T.-Y. Ho Limnology and Oceanography Letters 7(4), 363-371
112022Acute‑phase serum amyloid A for early detection of hepatocellular carcinoma in cirrhotic patients with low AFP levelJin-Lin Wu; Tung-Hung Su; Pei-Jer Chen; Yun-Ru Chen Scientific Reports 12, 5799
122022TAR DNA-binding protein 43 oligomers in physiology and pathologyYuh Shen Lye; Yun-Ru Chen IUBMB LIFE Early View
132022Hyperphosphorylation-mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric StageWan-Chin Chiang§; Yu-Sheng Fang§; Yuh-Shen Lye; Tzu-Yu Wong; Kiruthika Ganesan; Shih-Chieh Chou; Yun-Ru Chen ACS Chemical Neuroscience 13(17), 2599-2612
142021Time-Evolved SERS Signatures of DEP-Trapped Aβ and Zn2+Aβ Peptides Revealed by a Sub-10 nm Electrode NanogapVu, Katrin; Lee, Ming-Che; Blankenburg, Gerhard; Chang, Yu-Jen; Chu, Ming-Lee ; Erbe, Andreas; Lesser-Rojas, Leonardo; Chen, Yun-Ru ; Chou, Chia-Fu ANALYTICAL CHEMISTRY 93(49), 16320-16329
152021Amyloid-β40 E22K fibril in familial Alzheimer's disease is more thermostable and susceptible to seedingMing-Che Lee; Yi-Hung Liao; Shih-Hui Chen; Yun-Ru Chen IUBMB LIFE 74(8), 739-747
162020Effects of Dissolved Gases on the Amyloid Fibril MorphologyYa-Ling Chiang; Yu-Jen Chang; Yun-Ru Chen ; Ing-Shouh Hwang LANGMUIR 37(1), 516-523
172020TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s diseaseYao-Hsiang Shih; Ling-Hsien Tu; Ting-Yu Chang; Kiruthika Ganesan; Wei-Wei Chang; Pao-Sheng Chang; Yu-Sheng Fang; Yeh-Tung Lin; Lee-Way Jin; Yun-Ru Chen NATURE COMMUNICATIONS 11, 5950
182020Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosisPhillip Smethurst; Emmanuel Risse; Giulia E. Tyzack; Jamie S. Mitchell; Doaa M. Taha; Yun-Ru Chen ; Jia Newcombe; John Collinge; Katie Sidle; Rickie PataniBRAIN 143(2), 430-440
192020A Robust TDP-43 Knock-In Mouse Model of ALSShih-Ling Huang; Lien-Szu Wu; Min Lee; Chin-Wen Chang; Wei-Cheng Cheng; Yu-Sheng Fang; Yun-Ru Chen ; Pei-Lin Cheng; Che-Kun James ShenActa Neuropathologica Communications 8, 3