Results 1-12 of 12 (Search time: 0.003 seconds).
Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link | |
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1 | 2023 | N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry | Y. L. Wang; C. Y. Chang; N. S. Hsu; I. W. Lo; K. H. Lin; C. L. Chen; C. F. Chang ; Z. C. Wang; Y. Ogasawara; T. Dairi; C. Maruyama; Y. Hamano; T. L. Li | Nature communications 14(1), 2528 | |||
2 | 2022 | Intermolecular Interactions of Nucleoside Antibiotic Tunicamycin with On-Target MraYcb-TUN and Off-Target DPAGT1-TUN in the Active Sites Delineated by Quantum Mechanics/Molecular Mechanics Calculations | E. Astani; S. M. Zadeh; N. S. Hsu; K. H. Lin; S. Sardari; T. L. Li | ACS OMEGA 7(37), 32970-32987 | |||
3 | 2022 | Genetic and biochemical characterization of halogenation and drug transportation genes encoded in the albofungin biosynthetic gene cluster | Z. C. Wang; I. W. Lo; K. H. Lin; A. N. Cheng; S. M. Zadeh; Y. H. Huang; T. L. Li | APPLIED AND ENVIRONMENTAL MICROBIOLOGY 88(17), e0080622 | |||
4 | 2022 | β-Hydroxylation of α-amino-β-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin | S. M. Zadeh; M. H. Chen; Z. C. Wang; E. K. Astani; I. W. Lo; K. H. Lin; N. S. Hsu; K. Adhikari; S. Y. Lyu; H. Y. Tsai; Y. Terasawa; M. Yabe; K. Yamamoto; S. Ichikawa; T. L. Li | COMMUNICATIONS CHEMISTRY 5, 87 | |||
5 | 2022 | Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions | M. H. Chen; Y. S. Li; N. S. Hsu; K. H. Lin; Y. L. Wang; Z. C. Wang; C. F. Chang ; J. P. Lin; C. Y. Chang; T. L. Li | ACS CATALYSIS 12(3), 1945-1956 | |||
6 | 2022 | KasQ an epimerase primes the biosynthesis of aminoglycoside antibiotic kasugamycin and KasF/H acetyltransferases inactivate its activity | R. Rattinam; R. S. Basha; Y. L. Wang; Z. C. Wang; N. S. Hsu; K. H. Lin; S. Malek Zadeh; K. Adhikari; J. P. Lin; T. L. Li | BIOMEDICINES 10(2), 212 | |||
7 | 2022 | Dual-mechanism confers self-resistance to the antituberculosis antibiotic capreomycin | Y. C. Pan; Y. L. Wang; S. I. Toh; N. S. Hsu; K. H. Lin; Z. Xu; S. C. Huang; T. K. Wu; T. L. Li ; C. Y. Chang | ACS CHEMICAL BIOLOGY 17(1), 138-146 | |||
8 | 2020 | Chemoenzymatic synthesis and biological evaluation for bioactive molecules derived from bacterial benzoyl coenzyme A ligase and plant type III polyketide synthase | K. Adhikari; I. W. Lo; C. L. Chen; Y. L. Wang; K. H. Lin; S. MalekZadeh; R. Rattinam; Y. S. Li; C. J. Wu; T. L. Li | BIOMOLECULES 10(5), 738 | |||
9 | 2020 | Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity | K. H. Lin; S. Y. Lyu; H. W. Yeh; Y. S. Li; N. S. Hsu; C. M. Huang; Y. L. Wang; H. W. Shih; Z. C. Wang; C. J. Wu; T. L. Li | PROTEIN SCIENCE 29(7), 1655-1666 | |||
10 | 2019 | The flavin mononucleotide cofactor in α-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate-oxidation level | S. Y. Lyu; K. H. Lin; H. W. Yeh; Y. S. Li; C. M. Huang; Y. L. Wang; H. W. Shih; N. S. Hsu; C. J. Wu; T. L. Li | ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY 75, 918-929 | |||
11 | 2019 | Biochemical and structural explorations of α-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction | H. W. Yeh; K. H. Lin; S. Y. Lyu; Y. S. Li; C. M. Huang; Y. L. Wang; H. W. Shih; N. S. Hsu; C. J. Wu; T. L. Li | ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY 75(8), 733-742 | |||
12 | 2019 | Teicoplanin reprogrammed with the N-Acyl-glucosamine pharmacophore at the penultimate residue of aglycone acquires broad-spectrum antimicrobial activities effectively killing gram-positive and -negative pathogens | C. M. Huang; S. Y. Lyu; K. H. Lin; C. L. Chen; M. H. Chen; H. W. Shih; N. H. Hsu; I. W. Lo; Y. L. Wang; Y. S. Li; C. J. Wu; T. L. Li | ACS INFECTIOUS DISEASES 5(3), 430-442 |