研究成果

第 1 到 287 筆結果，共 287 筆。

公開日期題名作者關聯scopusWOS全文
1202401.故院長講座. 吳大猷院長科普講座「見證奈米大小的酵素在奈秒內修復受損的DNA」蔡明道 
2201801.故院長講座. 錢思亮院長講座「蛋白質結構的發展和最近的突破」蔡明道 
32017Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFATong-You W. Wei; Pei-Yu Wu; Ting-Jung Wu; Hsinan Hou; Wen-Chien Chou; Chieh-Lin Teng; Chih-Ru Lin; Jou-May M. Chen; Ting-Yang Lin; Hsiang-Chun Su; Chia-Chi F. Huang; Chang-Tze R. Yu; shih-lan Hsu; Hwei-Fang Tien; Ming-Daw Tsai Cancer Research 77(2), 494-508
42016TIFA as a Crucial Mediator for NLRP3 InflammasomeTing-Yang Lin; Tong-You Wade Wei; Shuai Li; Shen-Chih Wang; Ming He; Marcy Martin; Jiao Zhang; Tzu-Pin Shentu; Han Xiao; Jian Kang; Kuei-Chun Wang; Zhen Chen; Shu Chien; Ming-Daw Tsai ; John Y-J. ShyyPNAS 133(52), 15078-15083
52015A Ribonuclease Coordinates siRNA Amplification and mRNA Cleavage during RNAi.Hsin-Yue Tsai; Chun-Chieh G. Chen; Darryl Conte Jr; James J Moresco; Daniel A. Chaves; Shohei Mitani; John R. Yates III; Ming-Daw Tsai ; Craig C. MelloCell 160(3), 407-419
62015Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses.Weng, JH; Hsieh, YC; Huang, CC; Wei, TY; Lim, LH; Chen, YH; Ho, MR ; Wang, I; Huang, KF ; Chen, CJ; Tsai, MD Biochemistry 54(40), 6219-6229
72014PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase.Zih-Jie Shen; Pang-Hung Hsu; Yu-Tai Su; Chia-Wei Yang; Li Kao; Shun-Fu Tseng; Ming-Daw Tsai ; Shu-Chun TengNature Communications 5, 5312
82014Multiple complexes of long-aliphatic N-acyltransferases led to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics effectively killing VRE.Lyu, Syue-Yi; Liu, Yu-Chen; Chang, Chin-Yuan; Huang, Chuen-Jiuan; Chiu, Ya-Huang; Huang, Chun-Man; Hsu, Ning-Shian; Lin, Kuan-Hung; Wu, Chang-Jer; Tsai, Ming-Daw ; Li, Tsung-LinJ. Am. Chem. Soc. 136, 10989-10995
92014Ultrafast water dynamics at the interface of polymerase-DNA binding complex.Yi Yang; Yangzhong Qin; Qing Ding; Marina Bakhtina; Lijuan Wang; Ming-Daw Tsai ; Dongping ZhongBiochemistry 53, 5405-5413
102013Protein-phosphorylation Complexes in DNA Damage and Cancer SignalingTsai, Ming-Daw 
112013Protein-phosphoprotein complexes in DNA damage and cancer signalingTsai, Ming-Daw 
122013Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer MetastasisYu-Ching Teng; Cheng-Feng Lee; Ying-Shiuan Li; Yi-Ren Chen; Pei-Wen Hsiao; Meng-Yu Chan; Feng-Mao Lin; Hsien-Da Huang; Yen-Ting Chen; Yung-Ming Jeng; Qin Yan; Ming-Daw Tsai ; Li-Jung JuanCancer Research 73(15), 4711-4721
132013Ubc9 acetylation modulates distinct SUMO target modification and hypoxia responseHsieh, YL; Kuo, HY; Chang, CC; Naik, MT; Liao, PH; Ho, CC; Huang, TC; Jeng, JC; Hsu, PH; Tsai, MD ; Huang, TH; Shih, HMEMBO JOURNAL 32(6), 791-804
142013Reversible Acetylation Regulates Salt-Inducible Kinase (SIK2) and Its Function in AutophagyYang, Fu-Chia; Tan, Bertrand Chin-Ming; Chen, Wei-Hao; Lin, Ya-Huei; Huang, Jing-Yi; Chang, Hsin-Yun; Sun, Hui-Yu; Hsu, Pang-Hung; Liou, Gunn-Guang; Shen, C. -K. James; Chang, Ching-Jin; Han, Chau-Chung ; Tsai, Ming-Daw ; Lee, Sheng-ChungJOURNAL OF BIOLOGICAL CHEMISTRY 288(9), 6227-6237
152012Enzyme Mechanisms – from in vitro to in vivoTsai, Ming-Daw 
162012Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease.Wei, PC; Hsieh, YH; Su, MI; Jiang, XJ; Hsu, PH; Lo, WT; Weng, JY; Jeng, YM; Wang, JM; Chen, PL; Chang, YC; Lee, KF; Tsai, MD ; Shew, JY; Lee, WHMolecular cell 48(5), 747-59
172012How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53Tsai, Ming-Daw 
182012How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53Tsai, Ming-Daw 
192012How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53Tsai, Ming-Daw 
202012Intermolecular Binding between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF-κB ActivationHuang, CC; Weng, JH; Wei, TY; Wu, PY; Hsu, PH; Chen, YH; Wang, SC; Qin, D; Hung, CC ; Chen, ST ; Wang, AH ; Shyy, JY; Tsai, MD Molecular and cellular biology 32(14), 2664-2673
212012SUMOylation of Blimp‐1 is critical for plasma cell differentiationYing, H. -Y.; Su, S. -T.; Hsu, P. -H.; Chang, C. -C.; Lin, I-Y.; Tseng, Y. -H.; Tsai, M. -D. ; Shih, H. -M. ; Lin, K. -I EMBO reports 13(7), 631-637
222012A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint KinaseTsai, Ming-Daw 
232012Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharideLin, TL; Yang, FL; Yang, AS; Peng, HP; Li, TL ; Tsai, MD ; Wu, SH ; Wang, JTPLoS One 7(10), e46783
242012Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68Wu, HH; Wu, PY; Huang, KF ; Kao, YY; Tsai, MD Biochemistry 51(2), 575-577
252011Kinetic mechanism of active site assembly and chemical catalysis of DNA Polymerase βBalbo, PB; Wang, EC; Tsai, MD Biochemistry 50(45), 9865-9875
262011How some error prone DNA polymerases overcome Watson-Crick base pairingTsai, Ming-Daw 
272011FHA, a signaling domain with diverse specificities and functionsTsai, Ming-Daw 
282011Protein kinase A-mediated serine 35 phosphorylation dissociates histone H1.4 from mitotic chromosome.Chu, CS; Hsu, PH; Lo, PW; Scheer, E; Tora, L; Tsai, HJ; Tsai, MD ; Juan, LJJournal of biological chemistry 286(41), 35843-35851
292011The C-terminus of histone H2B is involved in chromatin compaction specifically at telomeres, independently of its monoubiquitylation at lysine 123Wang, CY; Hua, CY; Hsu, HE; Hsu, CL; Tseng, HY; Wright, DE; Hsu, PH; Jen, CH; Lin, CY; Wu, MY; Tsai, MD ; Kao, CF PloS one 6(7), e22209
302011Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancerLi, J; Poi, MJ; Tsai, MD BIOCHEMISTRY 50 (25), 5566–5582
312011The histone H3K36 demethylase Rph1/KDM4 regulates the expression of the photoreactivation gene PHR1Liang, Chung-Yi; Hsu, Pang-Hung; Chou, Dai-Fang; Pan, Chao-Yu; Wang, Long-Chi; Huang, Wei-Chieh; Tsai, Ming-Daw ; Lo, Wan-Sheng Nucleic Acids Research 39(10), 4151-4165
322011Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffoldsLiu, Y. C.; Li, Y. S.; Lyu, S. Y.; Hsu, L. J.; Chen, Y. H.; Huang, Y. T.; Chan, H. C.; Huang, C. J.; Chen, G. H.; Chou, C. C.; Tsai, M. D. ; Li, T. L. Nature chemical biology 7(5), 304-309
332011Regioselective deacetylation based on teicoplanin-complexed Orf2* crystal structures.Chan, HC; Huang, YT; Lyu, SY; Huang, CJ; Li, YS; Liu, YC; Chou, CC; Tsai, MD ; Li, TL Molecular bioSystems 7(4), 1224-1231
342011Structural and Mechanistic Bases for the G:G Specificity of ASFV DNA Polymerase XTsai, Ming-Daw 
352011Functions of Some Capsular Polysaccharide Biosynthetic Genes in Klebsiella pneumoniae NTUH K-2044Ho, JY; Lin, TL; Li, CY; Lee, A; Cheng, AN; Chen, MC; Wu, SH ; Wang, JT; Li, TL ; Tsai, MD PLoS One 6(7), e21664
362011Phosphorylation of NuSAP by Cdk1 regulates its interaction with microtubules in mitosis.Chou, HY; Wang, TH; Lee, SC; Hsu, PH; Tsai, MD ; Chang, CL; Jeng, YMCELL CYCLE 10(23), 4083-4089
372011E339…R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitorsShen, Y. -F.; Chen, Y. -H.; Chu, S. -Y.; Lin, M. -I.; Hsu, H. -T.; Wu, P. -Y.; Wu, C. -J.; Liu, H. -W.; Lin, F. -Y.; Lin, G.; Hsu, P. -H.; Yang, A. -S. ; Cheng, Y. -S. E.; Wu, Y. -T.; Wong, C. -H. ; Tsai, M. -D. Proceedings of the National Academy of Sciences of the United States of America 108(40), 16515-16520
382010Structure and Mechanism of Mutagenic DNA Polymerase XSu, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw 
392010A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase CascadeTsai, Ming-Daw 
402010Mechanism of High-Fidelity DNA Polymerase β and Low-Fidelity DNA Polymerase XTsai, Ming-Daw 
412010Counting the Phosphates of a Phosphorylation Site ClusterTsai, Ming-Daw 
422010Protein-Protein Interactions as Potential Drug TargetsTsai, Ming-Daw 
432010JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cellsLee, T. L.; Shyu, Y. C.; Hsu, P. C.; Wen, S. C.; Hsiao, W. Y.; Chang, C. W.; Tsai, M. D. ; Shen, C. -K. J. Proceedings of the national academy of sciences of the United States of America 107(1), 52-57
4420108.10 - Catalytic Mechanism of DNA PolymerasesRoettger, Michelle P.; Bakhtina, Marina; Kumar, Sandeep; Tsai, Ming-Daw Comprehensive Natural Products II: Chemistry and Biology (USA : Elsevier Oxford)
452010Database Search Algorithm for Identification of Intact Cross-Links in Proteins and Peptides Using Tandem Mass SpectrometryXu, H; Hsu, PH; Zhang, L; Tsai, MD ; Freitas, MAJOURNAL OF PROTEOME RESEARCH 9(7), 3384-3393
462010alpha-Helical burst on the folding pathway of FHA domains from Rad53 and Ki67Matsumura, Y; Shinjo, M; Mahajan, A; Tsai, MD ; Kihara, HBiochimie 92(8), 1031-1039
472010Nonhydrolyzable Analogs of Phosphatidylinositol as Ligands of Phospholipases C.Mihai, C; Yue, XJ; Zhao, L; Kravchuk, A; Tsai, MD ; Bruzik, KSNew J. Chem. 34, 925-933
482010Unique Catalytic Mechanism of Phosphatidylinositol-Specific Phospholipase C from Streptomyces antibioticusBai, C; Zhao, L; Tsai, MD ; Bruzik, KSJ. Am. Chem. Soc. 132(4), 1210–1211
492010Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteinsGuo, Y; Yuan, C; Tian, F; Huang, K; Weghorst, CM; Tsai, MD ; Li, JJ. Mol. Biol. 399(1),168-181
502010Unambiguous Determination of Isobaric Histone Modifications by Reverse-Phase Retention Time and High-Mass AccuracyYang, L; Tu, S; Ren, C; Bulloch, EM; Liao, CL; Tsai, MD ; Freitas, MAAnal. Biochem. 396(1),13-22
512010Global Analysis of Modifications of Human BK Virus Structural proteins by Mass SpectrometryFang, CY; Chen, HY; Wang, M; Chen, PL; Chang, CF; Chen, LS; Shen, CH; Ou, WC; Tsai, MD ; Hsu, PH; Chang, DVIROLOGY 402(1), 164-176
522010High-throughput Identification of Compounds Targeting Influenza RNA-dependent RNA Polymerase ActivitySu, C. -Y.; Cheng, T. -J. R.; Lin, M. -I.; Wang, S. -Y.; Huang, W. -I.; Lin-Chu, S. -Y.; Chen, Y. -H.; Wu, C. -Y.; Lai, M. M. C. ; Cheng, W. -C.; Wu, Y. -T.; Tsai, M. -D. ; Cheng, Y. -S. E.; Wong, C. -H. Proceedings of the National Academy of Sciences of the United States of America 107(45), 19151-19156
532009An Enzymologist's Approach to Histone DemethylasesTsai, Ming-Daw 
542009Structure and Mechanism of Mutagenic DNA Polymerase XSu, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw 
552009Structure and Mechanism of Mutagenic DNA Polymerase XSu, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw 
562009Structure and Mechanism of Mutagenic DNA Polymerase XSu, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw 
572009A Phosphate-Counting Mechanism for Sequential Activiation of a Checkpoint Kinase CascadeLee, Hyun; Yuan, Chunhua; Chen, Eric S. -W.; Mahajan, Anjali; Hammet, Andrew; Heierhorst, Jörg; Tsai, Ming-Daw 
582009Protein-phosphoprotein interactions of phosphothreonine-specific FHA domainsTsai, Ming-Daw 
592009Molecular Interactions of Biophosphates – from Catalysis to SignalingTsai, Ming-Daw 
602009FHA, a signaling domain with diverse specificitiesTsai, Ming-Daw 
612009Contribution of the Reverse Rate of the Conformational Step to Polymerase beta FidelityBakhtina, M; Roettger, MP; Tsai, MD Biochemistry 48(14), 3197-3208
622009Trans-Cyclization of Phosphatidylinositol Catalyzed by Phospholipase C from Streptomyces antibioticusBai C; Zhao, L; Rebecchi, M; Tsai, MD ; Bruzik, KSJ. Am. Chem. Soc. 131(24), 8362-8363
632009Humoral immunity against capsule polysaccharide protects the host from magA+ Klebsiella pneumoniae-induced lethal disease by evading Toll-like receptor 4 signalingWu, MF; Yang, CY; Lin, TL; Wang, JT; Yang, FL; Wu, SH ; Hu, BS; Chou, TY; Tsai, MD ; Lin, CH; Hsieh, SL Infection and immunity 77(2), 615-621
642009AMP-Activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser-633Chen, Z; Peng, IC; Sun, W; Su, MI; Hsu, PH; Fu, Y; Zhu, Y; DeFea, K; Pan, S; Tsai, MD ; Shyy, JYCIRCULATION RESEARCH 104(4), 496-505
652009Comparisons of the Conformational Stability of Cyclin-dependent Kinase (CDK) 4-Interacting Ankyrin Repeat (AR) ProteinsGuo, Y; Mahajan, A; Yuan, C; Joo, SH; Weghorst, CM; Tsai, MD ; Li, JBiochemistry 48(19), 4050-4062
662008The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motifTu, S; Teng, YC; Yuan, C; Wu, YT ; Chan, MY; Cheng, AN; Lin, PH; Juan, LJ ; Tsai, MD Nature Structural & Molecular Biology 15(4), 419-421
672008Structure and Function of the Phosphothreonine-Specific FHA DomainMahajan, A; Yuan, C; Lee, H; Chen, ES; Wu, PY; Tsai, MD Science Signaling 1(51), re12.
682008Mismatched and Matched dNTP Incorporation by DNA Polymerase β Proceed via Analogous Kinetic PathwaysRoettger, M. P.; Bakhtina, M.; Tsai, M. D. Biochemistry 47, 9718-9727
692008Mismatched dNTP Incorporation by DNA Polymerase β Does Not Proceed via Globally Different Conformational PathwaysTang, Kuo-Hsiang; Niebuhr, Marc; Tung, Chang-Shung; Chan, Hsiu-chien; Chou, Chia-Cheng; Tsai, Ming-Daw Nucleic Acids Res 36, 2948-2957
702008Structure and Function of 2:1 DNA Polymerase•DNA ComplexesTang, Kuo-Hsiang; Tsai, Ming-Daw JOURNAL OF CELLULAR PHYSIOLOGY 216, 315-320
712008Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering.Tang, Kuo-Hsiang; Niebuhr, Marc; Aulabaugh, Ann; Tsai, Ming-Daw Nucleic Acids Res 36, 849-860
722008Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.Lee, H; Yuan, C; Hammet, A; Mahajan, A; Chen, ES; Wu, MR; Su, MI; Heierhorst, J; Tsai, MD Mol. Cell 30, 767-778
732008Altered Order of Substrate Binding by DNA Polymerase X from African Swine Fever VirusKumar, S; Bakhtina, M; Tsai, MD Biochemistry 47, 7875-7887
742007Identification of Histone Demethylases in Saccharomyces cerevisiaeTu, S.; Bulloch, E. M. M.; Yang, L.; Ren, C.; Huang, W. -C.; Hsu, P. -H.; Chen, C. -H.; Liao, C. -L.; Yu, H. -M. ; Lo, Wan-Sheng ; Freitas, M. A.; Tsai, M. D. J. Biol. Chem 282(19), 14262-14271
752007Identification of in Vivo Phosphorylation Sites and Their Functional Significance in the Sodium Iodide SymporterVadysirisack, DD; Chen, ES; Zhang, Z; Tsai, MD ; Chang, GD; Jhiang, SMJ. Biol. Chem. 282, 36820-8
762007Human p16γ, a novel transcriptional variant of p16INK4A, coexpresses with p16INK4A in cancer cells and inhibits cell-cycle progressionLin, Y. C.; Diccianni, M. B.; Kim, Y.; Lin, H. H.; Lee, C. H.; Lin, R. J.; Joo, S. H.; Li, J.; Chuang, T. J.; Yang, A. S. ; Kuo, H. H.; Tsai, M. D. ; Yu, A. L.Oncogene 26(49), 7017-7027
772007Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus.Lamarche, B. J.; Kumar, S.; Tsai, M. D. Biochemistry 46, 3814-3825
782007Investigation of the conformational states of Wzz and the Wzz.O-antigen complex under near-physiological conditions.Tang, Kuo-Hsiang; Guo, Hongjie; Yi, Wen; Tsai, Ming-Daw ; Wang, Peng GeorgeBiochemistry 46, 11744-11752
792007A Unique FMN-linked Primary Alcohol Oxidase for Glycopeptide A40926 MaturationLi, Yi-Shan; Ho, Jin-Yuan; Huang, Chia-Chi; Lyu, Syue-Yi; Lee, Chun-Yen; Huang, Yu-Ting; Wu, Chang-Jer; Chan, Hsiu-Chien; Huang, Chuan-Jiuan; Hsu, Ning-Shian; Tsai, Ming-Daw ; Li, Tsung-LinJ. Am. Chem. Soc 129, 13384-13385
802007Human DNA Ligase IV and the Ligase IV/XRCC4 Complex: Analysis of Nick Ligation FidelityWang, Yu; Lamarche, Brandon J.; Tsai, Ming-Daw Biochemistry 46, 4962-4976
812007A Unified Kinetic Mechanism Applicable to Multiple DNA PolymerasesBakhtina, Marina; Roettger, Michelle P.; Kumar, Sandeep; Tsai, Ming-Daw Biochemistry 46, 5463-5472
822007Dissection of Protein-Protein Interaction and CDK4 Inhibition in the Oncogenic versus Tumor Suppressing Functions of Gankyrin and P16Mahajan, Anjali; Guo, Yi; Weghorst, Christopher M.; Yuan, Chunhua; Tsai, Ming-Daw ; Li, JunanJ. Mol. Biol 373, 990-1005
832006Ankyrin Repeat: A Unique Motif Mediating Protein--Protein InteractionsLi, J; Mahajan, A; Tsai, MD Biochemistry 45, 15168-15178
842006Contributions of an Endonuclease IV Homolog to DNA Repair in the African Swine Fever VirusLamarche, BJ; Tsai, MD BIOCHEMISTRY 45, 2790-2803
852006Mechanistic comparison of high-fidelity and error-prone DNA polymerases and ligases involved in DNA repair.Showalter, AK; Lamarche, BJ; Bakhtina, M; Su, MI; Tang, KH; Tsai, MD Chemical reviews 106(2), 340-60
862006Third Calcium Ion Found in an Inhibitor Bound Phospholipase A2Sekar, K; Gayathri, D; Velmurugan, D; Jeyakanthan, J; Yamane, T; Poi, MJ; Tsai, MD ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY D62, 392-397
872006Atomic Resolution Structure of the Double Mutant (K53,56M) of Bovine Pancreatic Phospholipase A2Sekar, K; Yogavel, M; Gayathri, D; Velmurugan, D; Krishna, R; Poi, MJ; Dauter, Z; Dauter, M; Tsai, MD Acta Crystallographica Section F-Structural Biology and Crystallization Communications F62, 1-5
882006Glycopeptide biosynthesis: Dbv21/Orf2 from dbv/tcp gene clusters are N-Ac-Glm teicoplanin pseudoaglycone deacetylases and Orf15 from cep gene cluster is a Glc-1-P thymidyltransferase.Ho, J. Y.; Huang, Y. T.; Wu, C. J.; Li, Y. S.; Tsai, M. D. ; Li, T. L.J. Am. Chem. Soc 128, 13694-13695
892006ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts.Lamarche, B. J.; Kumar, S.; Tsai, M. D. Biochemistry 45, 14826-14833
902006Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A2.Sekar, K; Yogavel, M; Kanaujia, SP; Sharma, A; Velmurugan, D; Poi, MJ; Dauter, Z; Tsai, MD ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 62(Pt 7), 717-24
912005Dissection of CDK4-binding and Transactivation Activities of p34SEI-1 and Comparison between Functions of p34SEI-1 and p16INK4Li, J; Muscarella, P; Joo, SH; Knobloch, TJ; Melvin, WS; Weghorst, CM; Tsai, MD Biochemistry 44, 13246-13256
922005FHA Domain−Ligand Interactions:  Importance of Integrating Chemical and Biological ApproachesMahajan, A; Yuan, C; Pike, BL; Heierhorst, J; Chang, CF ; Tsai, MD Journal of the American Chemical Society 127(42), 14572-14573
932005Sequential Phosphorylation and Multisite Interactions Characterize Specific Target Recognition by the FHA Domain of Ki-67Byeon, IJ; Li, H; Song, H; Gronenborn, AM; Tsai, MD Nature Structural and Molecular Biology 12, 987-993
942005An Error-Prone Viral DNA LigaseLamarche, B.; Showalter, A.; Tsai, M. D. Biochemistry 44, 8408-8417
952005Unusual Four-bond Secondary H/D Isotope Effect Supports a Short-Strong Hydrogen Bond between Phospholipase A2 and a Transition State Analog InhibitorYuan, C. H.; Tu, S.; Gelb, Michael H.; Tsai, M. D. Biochemistry 44, 4748-4754
962005Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta.Bakhtina, M; Lee, S; Wang, Y; Dunlap, C; Lamarche, B; Tsai, MD Biochemistry 44, 5177-5187
972005X-ray structure of the R69D phosphatidylinositol-specific phospholipase C enzyme: insight into the role of calcium and surrounding amino acids in active site geometry and catalysisApiyo, D; Zhao, L; Tsai, MD ; Selby, TLBiochemistry 44, 9980-9989
982005Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2Sekar, K; Rajakannan, V; Gayathri, D; Velmurugan, D; Poi, MJ; Dauter, M; Dauter, Z; Tsai, MD Acta Crystallograph Sect F Struct Biol Cryst Commun F61, 3-7
992004Gene Library Synthesis by Structure-based Combinatorial Protein Engineering (SCOPE)O’Maille, P. E.; Tsai, M. D. ; Noel, J. P.Methods in Enzymology 388, 75-91
1002004Enzyme Reaction Mechanisms: StereochemistryTsai, M. D. ; Zhao, L.; Lamarche, B.Encyclopedia in Biological Chemistry 2, 45-50
1012004Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiaePike, B. L.; Yongkiettrakul, S.; Tsai, M. D. ; Heierhorst, J.Mol Cell Biol 24, 2779-2788
1022004Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumorsLi, J; Weghorst, CM; Tsutsumi, M; Poi, MJ; Knobloch, TJ; Casto, BC; Melvin, WS; Tsai, MD ; Muscarella, PCarcinogenesis 25, 263-268
1032004Sequential phosphorylation of hNIFK by CDC2/cyclin B and GSK3 kinases in vitro leads to recognition by Ki67 FHA domain and suggests Ki67 is involved in cell cycle controlLi, H.; Song, H.; Tsai, M. D. (Submitted)
1042004The ligand specificity of yeast Rad53 FHA domains at the +3 position is determined by nonconserved residuesYongkiettrakul, S; Byeon, IJ; Tsai, MD Biochemistry 43, 3862-3869
1052004The nuclear protein p34(SEI-1) regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent mannerLi, J; Melvin, WS; Tsai, MD ; Muscarella, PBiochemistry 43, 4394-4399
1062004Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationshipYuan, C; Li, J; Mahajan, A; Poi, MJ; Byeon, IJ; Tsai, MD Biochemistry 43, 12152-12161
1072004The catalytic role of aspartate in a short strong hydrogen bond of the Asp274-His32 catalytic dyad in phosphatidylinositol-specific phospholipase C can be substituted by a chloride ionZhao, L; Liao, H; Tsai, MD J Biol Chem 279, 31995-32000
1082004Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functionsLi, H; Byeon, IJ; Ju, Y; Tsai, MD J Mol Biol 335, 371-381
1092003Biocatalysis and Biotransformation Enzymology in the Genomic Era – Editorial OverviewBegley, TP; Tsai, MD Curr. Opin. Chem. Biol 7, 228-229
1102003Engineering a catalytic metal binding site into a calcium-independent phosphatidylinositol-specific phospholipase C leads to enhanced stereoselectivityKravchuk, A. V.; Zhao, L.; Bruzik, K. S.; Tsai, M. D. Biochemistry 42, 2422-2430
1112003Interaction of monodisperse anionic amphiphiles with the i-face of secreted phospholipase A2Yu, B. Z.; Apitz-Castro, R.; Tsai, M. D. ; Jain, M. K.Biochemistry 42, 6293-6301
1122003A low-barrier hydrogen bond between histidine of secreted phospholipase A2 and a transition state analog inhibitorPoi, M. J.; Tomaszewski, J. W.; Yuan, C.; Dunlap, C. A.; Andersen, N. H.; Gelb, M. H.; Tsai, M. D. J Mol Biol 329, 997-1009
1132003Application of Bronsted-type LFER in the study of the phospholipase C mechanismMihai, C.; Kravchuk, A. V.; Tsai, M. D. ; Bruzik, K. S.J Am Chem Soc 125, 3236-3242
1142003A novel calcium-dependent bacterial phosphatidylinositol-specific phospholipase C displaying unprecedented magnitudes of thio effect, inverse thio effect, and stereoselectivityZhao, L; Liu, Y; Bruzik, KS; Tsai, MD J Am Chem Soc 125, 22-23
1152003Crystal structures of the free and anisic acid bound triple mutant of phospholipase A2Sekar, K; Vaijayanthi Mala, S; Yogavel, M; Velmurugan, D; Poi, MJ; Vishwanath, BS; Gowda, TV; Jeyaprakash, AA; Tsai, MD J Mol Biol 333, 367-376
1162003An NF-kappaB-specific inhibitor, IkappaBalpha, binds to and inhibits cyclin-dependent kinase 4Li, J; Joo, SH; Tsai, MD Biochemistry 42, 13476-13483
1172003Direct binding of the N-terminus of HTLV-1 tax oncoprotein to cyclin-dependent kinase 4 is a dominant path to stimulate the kinase activityLi, J; Li, H; Tsai, MD Biochemistry 42, 6921-6928
1182003Identification of potential binding sites for the FHA domain of human Chk2 by in vitro binding studiesQin, D; Lee, H; Yuan, C; Ju, Y; Tsai, MD Biochem Biophys Res Commun 311, 803-808
1192003Expression and characterization of Syrian golden hamster p16, a homologue of human tumor suppressor p16 INK4ALi, J; Qin, D; Knobloch, TJ; Tsai, MD ; Weghorst, CM; Melvin, WS; Muscarella, PBiochem Biophys Res Commun 304, 241-247
1202002Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2Rajakannan, V; Yogavel, M; Poi, MJ; Jeyaprakash, AA; Jeyakanthan, J; Velmurugan, D; Tsai, MD ; Sekar, KJ Mol Biol 324, 755-762
1212002A reexamination of the nucleotide incorporation fidelity of DNA polymerasesShowalter, A. K.; Tsai, M. D. Biochemistry 41, 10571-10576
1222002FHA: a signal transduction domain with diverse specificity and functionTsai, M. D. Structure 10, 887-888
1232002Structure-based combinatorial protein engineering (SCOPE)O’Maille, P. E.; Bakhtina, M.; Tsai, M. D. J Mol Biol 321, 677-691
1242002Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase betaDunlap, C. A.; Tsai, M. D. Biochemistry 41, 11226-11235
1252002Novel insights into the INK4-CDK4/6-Rb pathway: counter action of gankyrin against INK4 proteins regulates the CDK4-mediated phosphorylation of RbLi, J; Tsai, MD Biochemistry 41, 3977-3983
1262001“Learning Is a Lifelong Process” in Reflections on Multiliterate LivesDiane Dewhurst Belcher; Ulla Connor Eds.; Tsai, Ming-Daw Clevedon, England ; Buffalo, N.Y. : Multilingual Matters, 135-140
1272001Interfacial enzymology: the secreted phospholipase A(2)-paradigmBerg, O. G.; Gelb, M. H.; Tsai, M. D. ; Jain, M. K.Chem Rev 101, 2613-2654
1282001A DNA polymerase with specificity for five base pairsShowalter, A. K.; Tsai, M. D. J Am Chem Soc 123, 1776-1777
1292001Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexesArndt, J. W.; Gong, W.; Zhong, X.; Showalter, A. K.; Liu, J.; Dunlap, C. A.; Lin, Z.; Paxson, C.; Tsai, M. D. ; Chan, M. K.Biochemistry 40, 5368-5375
1302001Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53Yuan, C; Yongkiettrakul, S; Byeon, IJ; Zhou, S; Tsai, MD J Mol Biol 314, 563-575
1312001DNA polymerase beta: pre-steady-state kinetic analyses of dATP alpha S stereoselectivity and alteration of the stereoselectivity by various metal ions and by site-directed mutagenesisLiu, J; Tsai, MD Biochemistry 40, 9014-9022
1322001Solution structure of a viral DNA polymerase X and evidence for a mutagenic functionShowalter, A. K.; Byeon, I. J.; Su, M. I.; Tsai, M. D. Nat Struct Biol 8, 942-946
1332001Somatic INK4a-ARF locus mutations: a significant mechanism of gene inactivation in squamous cell carcinomas of the head and neckPoi, M. J.; Yen, T.; Li, J.; Song, H.; Lang, J. C.; Schuller, D. E.; Pearl, D. K.; Casto, B. C.; Tsai, M. D. ; Weghorst, C. M.Molecular Carcinogenesis 30, 26-36
1342001Mechanism of phosphatidylinositol-specific phospholipase C: origin of unusually high nonbridging thio effectsKravchuk, A. V.; Zhao, L.; Kubiak, R. J.; Bruzik, K. S.; Tsai, M. D. Biochemistry 40, 5433-5439
1352001Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexesByeon, I. J.; Yongkiettrakul, S.; Tsai, M. D. J Mol Biol 314, 577-588
1362001Involvement of the Arg-Asp-His catalytic triad in enzymatic cleavage of the phosphodiester bondKubiak, R. J.; Yue, X.; Hondal, R. J.; Mihai, C.; Tsai, M. D. ; Bruzik, K. S.Biochemistry 40, 5422-5432
1372000Kinetic Isotope Effects and Stereochemical Studies on a Ribonuclease Model: Hydrolysis Reactions of Uridine 3'-Nitrophenyl PhosphateHengge, AC; Bruzik, KS; Tobin, AE; Cleland, WW; Tsai, MD BIOORGANIC CHEMISTRY 28, 119-133
1382000Structural basis of the anionic interface preference and kcat* activation of pancreatic phospholipase A2Yu, B. Z.; Poi, M. J.; Ramagopal, U. A.; Jain, R.; Ramakumar, S.; Berg, O. G.; Tsai, M. D. ; Sekar, K.; Jain, M. K.Biochemistry 39, 12312-12323
1392000Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR dataYuan, C; Selby, TL; Li, J; Byeon, IJ; Tsai, MD Protein Sci 9, 1120-1128
1402000Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptidesWang, P; Byeon, IJ; Liao, H; Beebe, KD; Yongkiettrakul, S; Pei, D; Tsai, MD J Mol Biol 302, 927-940
1412000Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9Liao, H; Yuan, C; Su, MI; Yongkiettrakul, S; Qin, D; Li, H; Byeon, IJ; Pei, D; Tsai, MD J Mol Biol 304, 941-951
1422000Structure-Function Relationship of the INK4 Family of Tumor SuppressorsLi, J; Byeon, IJ; Poi, MJ; Ericson, K; Selby, T; O’Maille, P; Qin, D; Tsai, MD In: DNA Alterations in Cancer: Genetic and Epigenetic Changes 71-84
1432000Tumor suppressor INK4: quantitative structure-function analyses of p18INK4C as an inhibitor of cyclin-dependent kinase 4Li, J; Poi, MJ; Qin, D; Selby, TL; Byeon, IJ; Tsai, MD Biochemistry 39, 649-657
1442000DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelityKraynov, V. S.; Showalter, A. K.; Liu, J.; Zhong, X.; Tsai, M. D. Biochemistry 39, 16008-16015
1451999Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C)Yuan, C; Li, J; Selby, TL; Byeon, IJ; Tsai, MD J Mol Biol 294, 201-211
1461999Contributions of residues of pancreatic phospholipase A2 to interfacial binding, catalysis, and activationYu, BZ; Rogers, J; Tsai, MD ; Pidgeon, C; Jain, MKBiochemistry 38, 4875-4884
1471999Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4ALi, J; Byeon, IJ; Ericson, K; Poi, MJ; O’Maille, P; Selby, T; Tsai, MD Biochemistry 38, 2930-2940
1481999Pancreatic phospholipase A2: new views on old issuesYuan, C; Tsai, MD Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 1441, 215-222
1491999Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2Sekar, K; Biswas, R; Li, Y; Tsai, MD ; Sundaralingam, MActa Crystallographica Section D-Biological Crystallography 55, 443-447
1501999Nucleoside Monophosphate Kinases: Structure, Mechanism, and Substrate SpecificityYan, H; Tsai, MD Advances in Enzymology and Related Areas of Molecular Biology 73, 103-134
1511999Structural analysis of phospholipase A2 from functional perspective. 1. Functionally relevant solution structure and roles of the hydrogen-bonding networkYuan, C; Byeon, IJ; Li, Y; Tsai, MD Biochemistry 38, 2909-2918
1521999Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53Liao, H; Byeon, IJ; Tsai, MD J Mol Biol 294, 1041-1049
1531999Structural analysis of phospholipase A2 from functional perspective. 2. Characterization of a molten globule-like state induced by site-specific mutagenesisYuan, C; Byeon, IJ; Poi, MJ; Tsai, MD Biochemistry 38, 2919-2929
1541999Identification of a novel catalytic triad with dual functions in enzymatic cleavage of the P-O bondKubiak, R. J.; Hondal, R. J.; Yue, X. J.; Tsai, M. D. ; Bruzik, K. S.J Am Chem Soc 121, 488-489
1551998DNA polymerase beta. 5. Dissecting the functional roles of the two metal ions with Cr(III)dTTPZhong, X. J.; Patel, S. S.; Tsai, M. D. J Am Chem Soc 120, 235-236
15619981.72 A resolution refinement of the trigonal form of bovine pancreatic phospholipase A2Sekar, K; Sekharudu, C; Tsai, MD ; Sundaralingam, MActa Crystallographica Section D-Biological Crystallography 54, 342-346
1571998DNA polymerase beta: effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changesAhn, J; Kraynov, VS; Zhong, X; Werneburg, BG; Tsai, MD Biochem J 331, 79-87
1581998Cationic residues 53 and 56 control the anion-induced interfacial k*cat activation of pancreatic phospholipase A2Rogers, J; Yu, BZ; Tsai, MD ; Berg, OG; Jain, MKBiochemistry 37, 9549-9556
1591998Structure of the complex of bovine pancreatic phospholipase A2 with a transition-state analogueSekar, K; Kumar, A; Liu, X; Tsai, MD ; Gelb, MH; Sundaralingam, MActa Crystallographica Section D-Biological Crystallography 54, 334-341
1601998Mechanism of PI-Specific Phospholipase C. 5. Revealed by Protein Engineering and Phosphorothioate Analogs of PhosphatidylinositolHondal, R. J.; Zhao, Z.; Kravchuk, A. V.; Liao, H.; Riddle, S. R.; Bruzik, K. S.; Tsai, M. D. In: Phosphoinositides: Chemistry, Biochemistry and Biomedical Applications 718, 109-120
1611998Mechanism of phosphatidylinositol-specific phospholipase C: a unified view of the mechanism of catalysisHondal, R. J.; Zhao, Z.; Kravchuk, A. V.; Liao, H.; Riddle, S. R.; Yue, X.; Bruzik, K. S.; Tsai, M. D. Biochemistry 37, 4568-4580
1621998Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4Byeon, I. J.; Li, J.; Ericson, K.; Selby, T. L.; Tevelev, A.; Kim, H. J.; O’Maille, P.; Tsai, M. D. Mol Cell 1, 421-431
1631997Use of Unnatural Amino Acids to Probe the Importance of the Aromaticity in Tyrosine-95 and the Ring Size in Proline-17 in Adenylate KinaseZhao, Z; Liu, X; Shi, Z; Huang, B; Jiang, RT; Tsai, MD Youji Huaxue 17, 20-23
1641997DNA polymerase beta: multiple conformational changes in the mechanism of catalysisZhong, X; Patel, SS; Werneburg, BG; Tsai, MD Biochemistry 36, 11891-11900
1651997Mechanism of phosphatidylinositol-phospholipase C .2. Reversal of a thio effect by site-directed mutagenesisHondal, RJ; Bruzik, KS; Zhao, Z; Tsai, MD J Am Chem Soc 119, 5477-5478
1661997SYNTHESIS OF ENANTIOMERICALLY PURE PHOSPHOROTHIOLATE ASSAY SUBSTRATE FOR PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE CMihai, C; Mataka, J; Riddle, S; Tsai, MD ; Bruzik, KSBioorganic & Medicinal Chemistry Letters 7, 1235-1238
1671997DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutantAhn, J; Werneburg, BG; Tsai, MD Biochemistry 36, 1100-1107
1681997Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99Sekar, K; Yu, BZ; Rogers, J; Lutton, J; Liu, X; Chen, X; Tsai, MD ; Jain, MK; Sundaralingam, MBiochemistry 36, 3104-3114
1691997Phosphatidylinositol-specific phospholipase C .3. Elucidation of the catalytic mechanism and comparison with ribonuclease A1Hondal, R. J.; Zhao, Z.; Riddle, S. R.; Kravchuk, A. V.; Liao, H.; Bruzik, K. S.; Tsai, M. D. J Am Chem Soc 119, 9933-9934
1701997Natural Product Chemistry: From Plants to HumanTsai, M. D. Journal of the Chinese Chemical Society 44, 183-186
1711997DNA polymerase beta: analysis of the contributions of tyrosine-271 and asparagine-279 to substrate specificity and fidelity of DNA replication by pre-steady-state kineticsKraynov, V. S.; Werneburg, B. G.; Zhong, X.; Lee, H.; Ahn, J.; Tsai, M. D. Biochem J 323, 103-111
1721997Phosphatidylinositol-specific phospholipase C: kinetic and stereochemical evidence for an interaction between arginine-69 and the phosphate group of phosphatidylinositolHondal, R. J.; Riddle, S. R.; Kravchuk, A. V.; Zhao, Z.; Liao, H.; Bruzik, K. S.; Tsai, M. D. Biochemistry 36, 6633-6642
1731996Perspectives on Protein EngineeringHuang, B.; Schaeffer, C. J.; Tsai, M. D. 
1741996Splase: The Design of a New Restriction Enzyme with Specificity for Sp1 Binding SitesHuang, B; Schaeffer, CJ; Tsai, MD Perspectives on Protein Engineering 3
1751996Structure-Function Relationship of Adenylate Kinase. 19. Glutamine-101 in AMP SpecificityBeichner, S; Byeon, IJ; Tsai, MD PEPTIDES: Chemistry, Structure, and Biology 721-723
1761996Design, synthesis and biochemical applications of analogs of phosphatidylinositolBhamare, N; Wang, YP; Tsai, MD ; Bruzik, KSPhosphorus Sulfur and Silicon and the Related Elements 10991-4), 317-320
1771996Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroismTevelev, A; Byeon, IJ; Selby, T; Ericson, K; Kim, HJ; Kraynov, V; Tsai, MD Biochemistry 35, 9475-9487
1781996Mechanism of adenylate kinase .20. Probing the importance of the aromaticity in tyrosine-95 and the ring size in proline-17 with unnatural amino acidsZhao, Z; Liu, XH; Shi, ZT; Danley, L; Huang, BH; Jiang, RT; Tsai, MD J Am Chem Soc 118, 3535-3536
1791996Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interfaceHuang, B; Yu, BZ; Rogers, J; Byeon, IJ; Sekar, K; Chen, X; Sundaralingam, M; Tsai, MD ; Jain, MKBiochemistry 35, 12164-12174
1801996Splase: a new class IIS zinc-finger restriction endonuclease with specificity for Sp1 binding sitesHuang, B; Schaeffer, CJ; Li, Q; Tsai, MD Journal of Protein Chemistry 15, 481-489
1811996Effects of Glycosylation of a Peptide Epitope from HTLV-1 gp46 on Structure and ImmunogenicityConrad, S. F.; Byeon, I. J. L; DiGeorge, A. M.; Lairmore, M. D.; Tsai, M. D. ; Kaumaya, P. T. P.Chem Struct Biol, Proc Am Pept Symp 448-449
1821996DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelityWerneburg, B. G.; Ahn, J.; Zhong, X.; Hondal, R. J.; Kraynov, V. S.; Tsai, M. D. Biochemistry 35, 7041-7050
1831996Binding proteins on synaptic membranes for certain phospholipases A2 with presynaptic toxicityTzeng, M. C.; Yen, C. H.; Tsai, M. D. Adv Exp Med Biol 391, 271-278
1841996Synthesis of inositol phosphodiesters by phospholipase C-catalyzed transesterificationBruzik, K. S.; Guan, Z. W.; Riddle, S.; Tsai, M. D. J Am Chem Soc 118, 7679-7688
1851995Phospholipase A2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMRLiu, X; Zhu, H; Huang, B; Rogers, J; Yu, BZ; Kumar, A; Jain, MK; Sundaralingam, M; Tsai, MD Biochemistry 34, 7322-7334
1861995Phospholipase A2 engineering. The roles of disulfide bonds in structure, conformational stability, and catalytic functionZhu, H; Dupureur, CM; Zhang, X; Tsai, MD Biochemistry 34, 15307-15314
1871995Conversion of bovine pancreatic phospholipase A2 at a single site into a competitor of neurotoxic phospholipases A2 by site-directed mutagenesisTzeng, MC; Yen, CH; Hseu, MJ; Dupureur, CM; Tsai, MD J Biol Chem 270, 2120-2123
1881995Mechanism of adenylate kinase. The ""essential lysine"" helps to orient the phosphates and the active site residues to proper conformationsByeon, L; Shi, Z; Tsai, MD Biochemistry 34, 3172-3182
1891995Binding proteins on synaptic membranes for crotoxin and taipoxin, two phospholipases A2 with neurotoxicityTzeng, M. C.; Yen, C. H.; Hseu, M. J.; Tseng, C. C.; Tsai, M. D. ; Dupureur, C. M.Toxicon 33, 451-457
1901995Manipulating phosphorus stereospecificity of adenylate kinase by site-directed mutagenesisTsai, M. D. ; Jiang, R. T.; Dahnke, T.; Shi, Z.Methods in Enzymology 249, 425-443
1911995Immunogenicity and conformational properties of an N-linked glycosylated peptide epitope of human T-lymphotropic virus type 1 (HTLV-I)Conrad, S. F.; Byeon, I. J.; DiGeorge, A. M.; Lairmore, M. D.; Tsai, M. D. ; Kaumaya, P. T.Biomed Pept Proteins Nucleic Acids 1, 83-92
1921994Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural waterKumar, A; Sekharudu, C; Ramakrishnan, B; Dupureur, CM; Zhu, H; Tsai, MD ; Sundaralingam, MProtein Sci 3, 2082-2088
1931994A small, high-copy-number vector suitable for both in vitro and in vivo gene expressionHuang, B; Shi, Z; Tsai, MD Gene 151, 143-145
1941994Mechanism of adenylate kinase. The conserved aspartates 140 and 141 are important for transition state stabilization instead of substrate-induced conformational changesDahnke, T; Tsai, MD J Biol Chem 269, 8075-8081
1951994Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-49Li, Y; Yu, BZ; Zhu, H; Jain, MK; Tsai, MD Biochemistry 33, 14714-14722
1961994Toward the mechanism of phosphoinositide-specific phospholipases CBruzik, K. S.; Tsai, M. D. Bioorganic & Medicinal Chemistry 2, 49-72
1971994Are D- and L-chiro-phosphoinositides substrates of phosphatidylinositol-specific phospholipase C?Bruzik, K. S.; Hakeem, A. A.; Tsai, M. D. Biochemistry 33, 8367-8374
1981993Mechanism of adenylate kinase. What can be learned from a mutant enzyme with minor perturbation in kinetic parameters?Shi, Z; Byeon, IJ; Jiang, RT; Tsai, MD Biochemistry 32, 6450-6458
1991993Mechanism of adenylate kinase. 1H, 13C, and 15N NMR assignments, secondary structures, and substrate binding sitesByeon, I. J.; Yan, H.; Edison, A. S.; Mooberry, E. S.; Abildgaard, F.; Markley, J. L.; Tsai, M. D. Biochemistry 32, 12508-12521
2001993Phospholipase A2 engineering. 10. The aspartate...histidine catalytic diad also plays an important structural roleLi, Y. S.; Tsai, M. D. J Am Chem Soc 115, 8523-8526
2011992Mechanism of adenylate kinase. Structural and functional roles of the conserved arginine-97 and arginine-132Dahnke, T; Shi, Z; Yan, H; Jiang, RT; Tsai, MD Biochemistry 31, 6318-6328
2021992Crystal structure of the Y52F/Y73F double mutant of phospholipase A2: increased hydrophobic interactions of the phenyl groups compensate for the disrupted hydrogen bonds of the tyrosinesSekharudu, C; Ramakrishnan, B; Huang, B; Jiang, RT; Dupureur, CM; Tsai, MD ; Sundaralingam, MProtein Sci 1, 1585-1594
2031992Interfacial catalysis by phospholipase A2: the rate-limiting step for enzymatic turnoverJain, M. K.; Yu, B. Z.; Rogers, J.; Gelb, M. H.; Tsai, M. D. ; Hendrickson, E. K.; Hendrickson, H. S.Biochemistry 31, 7841-7847
2041992Phospholipase A2 engineering. 6. Single amino acid substitutions of active site residues convert the rigid enzyme to highly flexible conformational statesDupureur, C. M.; Li, Y. S.; Tsai, M. D. J Am Chem Soc 114, 2748-2749
2051992Efficient and Systematic Syntheses of Enantiomerically Pure and Regiospecifically Protected MyoinositolsBruzik, K. S.; Tsai, M. D. J Am Chem Soc 114, 6361-6374
2061992Phospholipids chiral at phosphorus. Stereochemical mechanism for the formation of inositol 1-phosphate catalyzed by phosphatidylinositol-specific phospholipase CBruzik, K. S.; Morocho, A. M.; Jhon, D. Y.; Rhee, S. G.; Tsai, M. D. Biochemistry 31, 5183-5193
2071992Phospholipase A2 engineering. Structural and functional roles of highly conserved active site residues tyrosine-52 and tyrosine-73Dupureur, C. M.; Yu, B. Z.; Jain, M. K.; Noel, J. P.; Deng, T.; Li, Y.; Byeon, I. J.; Tsai, M. D. Biochemistry 31, 6402-6413
2081992Modification of a Bruker AM-600 Spectrometer for Double and Triple Resonance Three Dimensional and Four Dimensional Experiments Illustrated with Chicken Adenylate Kinase Resonance AssignmentsMooberry, E. S.; Edison, A. S.; Abildgaard, F.; Markley, J. L.; Byeon, I. J. L.; Tsai, M. D. Proceedings of the International Symposium on Spectroscopy and Structure of Molecules and Nuclei 375-380
2091992Practical Synthesis of Enantiomerically Pure myo-Inositol DerivativesBruzik, K. S.; Myers, J.; Tsai, M. D. Tetrahedron Lett 33, 1009-1012
2101992Phospholipase A2 engineering. The structural and functional roles of aromaticity and hydrophobicity in the conserved phenylalanine-22 and phenylalanine-106 aromatic sandwichDupureur, C. M.; Yu, B. Z.; Mamone, J. A.; Jain, M. K.; Tsai, M. D. Biochemistry 31, 10576-10583
2111991Mechanism of Adenylate Kinase .12. Prediction and Demonstration of Enhancement of Phosphorus Stereospecificity by Site-Directed MutagenesisDahnke, T; Jiang, RT; Tsai, MD J Am Chem Soc 113, 9388-9389
2121991Mechanism of adenylate kinase. Demonstration of a functional relationship between aspartate 93 and Mg2+ by site-directed mutagenesis and proton, phosphorus-31, and magnesium-25 NMRYan, H. G.; Tsai, M. D. Biochemistry 30, 5539-5546
2131991Mechanism of adenylate kinase: site-directed mutagenesis versus X-ray and NMRTsai, M. D. ; Yan, H. G.Biochemistry 30, 6806-6818
2141991Phospholipase stereospecificity at phosphorusBruzik, K. S.; Tsai, M. D. Methods in Enzymology 197, 258-269
2151991Phosphorothioate Analogs of Phosphatidylinositol and Inositol 1,2-Cyclic Phosphate - Application to the Mechanism of Phospholipase-CBruzik, K. S.; Lin, G. L.; Tsai, M. D. ACS Symposium Series 463, 172-185
2161991Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substratesNoel, J. P.; Bingman, C. A.; Deng, T. L.; Dupureur, C. M.; Hamilton, K. J.; Jiang, R. T.; Kwak, J. G.; Sekharudu, C.; Sundaralingam, M.; Tsai, M. D. Biochemistry 30, 11801-11811
2171991Mechanism of Adenylate Kinase .10. Reversing Phosphorus Stereospecificity by Site-Directed MutagenesisJiang, R. T.; Dahnke, T.; Tsai, M. D. J Am Chem Soc 113, 5485-5486
2181990Phospholipase A2 engineering. 4. Can the active-site aspartate-99 function alone?Dupureur, C. M.; Deng, T. L.; Kwak, J. G.; Noel, J. P.; Tsai, M. D. J Am Chem Soc 112, 7074-7076
2191990Phospholipids Chiral at Phosphorus .19. Synthesis and Configurational Assignment of Phosphorothioate Analogs of PhosphatidylserineLoffredo, W. M.; Tsai, M. D. Bioorg Chem 18, 78-84
2201990Phospholipids chiral at phosphorus. Stereochemical mechanism of reactions catalyzed by phosphatidylinositide-specific phospholipase C from Bacillus cereus and guinea pig uterusLin, G. L.; Bennett, C. F.; Tsai, M. D. Biochemistry 29, 2747-2757
2211990Phospholipase A2 engineering. 3. Replacement of lysine-56 by neutral residues improves catalytic efficiency significantly, alters substrate specificity, and clarifies the mechanism of interfacial recognitionNoel, J. P.; Deng, T.; Hamilton, K. J.; Tsai, M. D. J Am Chem Soc 112, 3704-3706
2221990Phospholipids Chiral at Phosphorus. 22. Phospholipids Chiral at Phosphorus - Synthesis of Dioleoylthiophosphatidylcholine and Stereospecificity of Lecithin-Cholesterol AcyltransferaseRosariojansen, T; Pownal, H; Jiang, RT; Tsai, MD Bioorg Chem 18, 179-184
2231990A novel expression vector for high-level synthesis and secretion of foreign proteins in Escherichia coli: overproduction of bovine pancreatic phospholipase A2Deng, TL; Noel, JP; Tsai, MD Gene 93, 229-234
2241990Mechanism of adenylate kinase. Structural and functional demonstration of arginine-138 as a key catalytic residue that cannot be replaced by lysineYan, H. G.; Shi, Z. T.; Tsai, M. D. Biochemistry 29, 6385-6392
2251990Mechanism of adenylate kinase. Are the essential lysines essential?Tian, G. C.; Yan, H. G.; Jiang, R. T.; Kishi, F.; Nakazawa, A.; Tsai, M. D. Biochemistry 29, 4296-4304
2261990Mechanism of adenylate kinase. Critical evaluation of the X-ray model and assignment of the AMP siteYan, H. G.; Dahnke, T.; Zhou, B. B.; Nakazawa, A.; Tsai, M. D. Biochemistry 29, 10956-10964
2271989Mechanism of adenylate kinase. Is there a relationship between local substrate dynamics, local binding energy, and the catalytic mechanism?C. R. Sanders; Tian, G. C.; Tsai, M. D. Biochemistry 28, 9028-9043
2281989Ligand-protein interactions via nuclear magnetic resonance of quadrupolar nucleiC. R. Sanders; Tsai, M. D. Methods in Enzymology 177, 317-333
2291989Phospholipase A2 engineering: design, synthesis, and expression of a gene for bovine (pro)phospholipase A2Noel, JP; Tsai, MD J Cell Biochem 40, 309-320
2301989Phospholipids chiral at phosphorus. 18. Stereochemistry of phosphatidylinositide-specific phospholipase CLin, G; Tsai, MD J Am Chem Soc 111, 3099-3101
2311988Phospholipids chiral at phosphorus. Synthesis and stereospecificity of phosphorothioate analogues of platelet-activating factorJansen, T. Rosario; Jiang, R. T.; Tsai, M. D. ; Hanahan, D. J.Biochemistry 27, 4619-4624
2321988Phospholipids chiral at phosphorus. Characterization of the sub-gel phase of thiophosphatidylcholines by use of X-ray diffraction, phosphorus-31 nuclear magnetic resonance, and Fourier transform infrared spectroscopySarvis, H. E.; Loffredo, W.; Dluhy, R. A.; Hernqvist, L.; Wisner, D. A.; Tsai, M. D. Biochemistry 27, 4625-4631
2331988Mechanism of Adenylate Kinase .3. Use of Deuterium Nmr to Show Lack of Correlation between Local Substrate Dynamics and Local Binding-EnergyC. R. Sanders; Tsai, M. D. J Am Chem Soc 110, 3323-3324
2341988Steric Course of the Reaction Catalyzed by Phosphatidylserine Decarboxylase from Escherichia-ColiNo, Z. S.; Sanders, C. R.; Dowhan, W.; Tsai, M. D. Bioorg Chem 16, 184-188
2351988Use of short-chain cyclopentano-phosphatidylcholines to probe the mode of activation of phospholipase A2 from bovine pancreas and bee venomLin, G; Noel, J; Loffredo, W; Stable, HZ; Tsai, MD J Biol Chem 263, 13208-13214
2361988Mechanism of adenylate kinase. Histidine-36 is not directly involved in catalysis, but protects cysteine-25 and stabilizes the tertiary structureTian, GC; Sanders, CR 2nd; Kishi, F; Nakazawa, A; Tsai, MD Biochemistry 27, 5544-5552
2371987Biophosphates and Their Analogues, Synthesis, Structure, Metabolism and ActivityTsai, M. D. ; Bruzik, K. S.; Wisner, D.; Liu, S. H.
2381987Phospholipids Chiral at Phosphorus. 14. Stereochemical Effects on the Thermotropic Properties of Thiophosphatidylcholines and ThiosphingomyelinsTsai, M. D. ; Bruzik, K. S.; Wisner, D.; Liu, S. H.In: Biophosphates and Their Analogues, Synthesis, Structure, Metabolism and Activity 561-570
2391987Phospholipids Chiral at Phosphorus .13. Stereochemical Comparison of Phospholipase-A2, Lecithin-Cholesterol Acyl Transferase, and Platelet-Activating-FactorRosariojansen, T.; Pownall, H. J.; Noel, J. P.; Tsai, M. D. Phosphorus Sulfur and Silicon and the Related Elements 30, 601-604
2401987Is the binding of magnesium (II) to calmodulin significant? An investigation by magnesium-25 nuclear magnetic resonanceTsai, M. D. ; Drakenberg, T.; Thulin, E.; Forsen, S.Biochemistry 26, 3635-3643
2411987A calorimetric study of the thermotropic behavior of pure sphingomyelin diastereomersBruzik, K. S.; Tsai, M. D. Biochemistry 26, 5364-5368
2421987Phospholipids chiral at phosphorus. Steric course of the reactions catalyzed by phosphatidylserine synthase from Escherichia coli and yeastRaetz, C. R.; Carman, G. M.; Dowhan, W.; Jiang, R. T.; Waszkuc, W.; Loffredo, W.; Tsai, M. D. Biochemistry 26, 4022-4027
2431987Magnesium Binding to Calcium-Binding Proteins: A Regulatory Function?Drakenberg, T; Forsen, S; Thulin, E; Tsai, MD In: Calcium-Binding Proteins in Health and Disease 430-432
2441986Mechanisms of Enzymatic Reactions: StereochemistryTsai, M. D. ; Bruzik, K.; Hart, J.; Jiang, R. T.; Jansen, T. Rosario; Tsai, T. C.; Wisner, D. A.
2451986Phospholipids chiral at phosphorus: Fourier-transform infrared study on the gel-liquid crystalline transition of chiral thiophosphatidylcholineChang, S. B.; Alben, J. O.; Wisner, D. A.; Tsai, M. D. Biochemistry 25, 3435-3440
2461986Phospholipids Chiral at Phosphorus .12. Configurational Effect on the Thermotropic Properties of Chiral DipalmitoylthiophosphatidylcholineWisner, D. A.; Rosariojansen, T.; Tsai, M. D. J Am Chem Soc 108, 8064-8068
2471986Phospholipids Chiral at Phosphorus. 10. Use of Chiral Thiophospholipids to Study the Mechanism of Phospholipase A2Tsai, M. D. ; Bruzik, K.; Hart, J.; Jiang, R. T.; Jansen, T. Rosario; Tsai, T. C.; Wisner, D. A.In: Mechanisms of Enzymatic Reactions: Stereochemistry 115-126
2481985Metal-nucleotide interactions. 3. Oxygen-17, phosphorus-31, and proton NMR studies on the interaction of scandium(III), lanthanum(III), and lutetium(III) with adenosine 5'-triphosphateShyy, YJ; Tsai, TC; Tsai, MD Journal of the American Chemical Society 107(12), 3478-3484
2491985Mechanism of adenylate kinase. 1. Use of oxygen-17 NMR to study the binding properties of substratesWisner, D. A.; Steginsky, C. A.; Shyy, Y. J.; Tsai, M. D. J Am Chem Soc 107, 2814-2815
2501985Phospholipids chiral at phosphorus. Use of chiral thiophosphatidylcholine to study the metal-binding properties of bee venom phospholipase A2Tsai, T. C.; Hart, J.; Jiang, R. T.; Bruzik, K.; Tsai, M. D. Biochemistry 24, 3180-3188
251198431P NMR: Principles and ApplicationsTsai, M. D. 
2521984Phospholipids chiral at phosphorus. Properties of small unilamellar vesicles of chiral thiophosphatidylcholineTsai, T. C.; Jiang, R. T.; Tsai, M. D. Biochemistry 23, 5564-5570
2531984Use of Chiral thiophosphates and the Stereochemistry of Enzymatic Phosphoryl TransferTsai, M. D. In: 31P NMR: Principles and Applications 175-197
2541984Stereochemistry of Biological Reactions at Proprochiral CentersFloss, H. G.; Tsai, M. D. ; Woodard, R. W.Topics in Stereochemistry 15, 253-321
2551984Phospholipids chiral at phosphorus. Absolute configuration of chiral thiophospholipids and stereospecificity of phospholipase DJiang, R. T.; Shyy, Y. J.; Tsai, M. D. Biochemistry 23, 1661-1667
2561984Phospholipids chiral at phosphorus. Synthesis of chiral phosphatidylcholine and stereochemistry of phospholipase DBruzik, K; Tsai, MD Biochemistry 23, 1656-1661
2571984Phospholipids chiral at phosphorus. 5. Synthesis and configurational analysis of chiral [17O,18O]phosphatidylethanolamineBruzik, K; Tsai, MD J Am Chem Soc 106, 747-754
2581983NMR Methods Involving Oxygen Isotopes in BiophosphatesTsai, M. D. ; Bruzik, K.Biological Magnetic Resonance 5, 129-181
2591983Effects of oxygen-17 and oxygen-18 on phosphorus-31 NMR: further investigation and applicationsSammons, R. D.; Frey, P. A.; Bruzik, K.; Tsai, M. D. J Am Chem Soc 105, 5455-5461
2601983Phospholipids Chiral at Phosphorus .4. Could Membranes Be Chiral at Phosphorus?Tsai, M. D. ; Jiang, R. T.; Bruzik, K.J Am Chem Soc 105, 2478-2480
2611983Phospholipids Chiral at Phosphorus - Synthesis, Absolute-Configurations and ApplicationsBruzik, K. S.; Jiang, R. T.; Tsai, M. D. Phosphorus Sulfur and Silicon and the Related Elements 18, 369-372
2621983Phospholipids chiral at phosphorus. Preparation and spectral properties of chiral thiophospholipidsBruzik, K; Jiang, RT; Tsai, MD Biochemistry 22, 2478-2486
2631982Use of 31P(18O), 31P(17O), and 17O NMR methods to study enzyme mechanisms involving phosphorusTsai, M. D. Methods in Enzymology 87, 235-279
2641982Does the magnesium(II) ion interact with the alpha-phosphate of adenosine triphosphate? An investigation by oxygen-17 nuclear magnetic resonanceHuang, S. L.; Tsai, M. D. Biochemistry 21, 951-959
2651982Phospholipids chiral at phosphorus. 1. Stereochemistry of transphosphatidylation catalyzed by phospholipase DBruzik, K; Tsai, MD J Am Chem Soc 104, 863-865
2661982Phospholipids Chiral at Phosphorus .2. Preparation, Property, and Application of Chiral ThiophospholipidsBruzik, K; Gupte, SM; Tsai, MD J Am Chem Soc 104, 4682-4684
2671981First observation of amino acid side chain dynamics in membrane proteins using high field deuterium nuclear magnetic resonance spectroscopyKinsey, R. A.; Kintanar, A.; Tsai, M. D. ; Smith, R. L.; Janes, N.; Oldfield, E.J Biol Chem 256, 4146-4149
2681981Protein crystals, membrane proteins and membrane lipids. Recent advances in the study of their static and dynamic structures using nuclear magnetic resonance spectroscopic techniquesOldfield, E; Janes, N; Kinsey, R; Kintanar, A; Lee, RW; Rothgeb, TM; Schramm, S; Skarjune, R; Smith, R; Tsai, MD Biochemical Society Symposium (46), 155-181
2691980Chirality at a pro-pro-prochiral phosphorus center. Stereochemical course of the 5'-nucleotidase-catalyzed reactionTsai, MD ; Chang, TTJ Am Chem Soc 102, 5416-5418
2701980Stereochemistry of the hydrolysis of adenosine 5'-thiophosphate catalyzed by venom 5'-nucleotidaseTsai, MD Biochemistry 19, 5310-5316
2711980Applicability of the phosphorus-31 (oxygen-17) nuclear magnetic resonance method in the study of enzyme mechanism involving phosphorusTsai, M. D. ; Huang, S. L.; Kozlowski, J. F.; Chang, C. C.Biochemistry 19, 3531-3536
2721980Stereochemical course of the transmethylation catalyzed by catechol O-methyltransferaseWoodard, R. W.; Tsai, M. D. ; Floss, H. G.; Crooks, P. A.; Coward, J. K.J Biol Chem 255, 9124-9127
2731979Chiral methyl groupsFloss, HG; Tsai, MD Adv Enzymol Relat Areas Mol Biol 50, 243-302
2741979TransmethylationFloss, H. G.; Mascaro, L.; Tsai, M. D. ; Woodard, R. W.
2751979Stereochemistry and mechanism of reactions catalyzed by indolyl-3-alkane alpha-hydroxylaseTsai, M. D. ; Floss, H. G.; Rosenfeld, H. J.; Roberts, J.J Biol Chem 254, 6437-6443
2761979Use of phosphorus-31 nuclear magnetic resonance to distinguish bridge and nonbridge oxygens of oxygen-17-enriched nucleoside triphosphates. Stereochemistry of acetate activation by acetyl coenzyme A synthetaseTsai, M. D. Biochemistry 18, 1468-1472
2771979Stereochemistry of Enzymatic TransmethylationFloss, H. G.; Mascaro, L.; Tsai, M. D. ; Woodard, R. W.In: Transmethylation 135-141
2781978Conformation-reactivity relationship for pyridoxal Schiff's bases. Rates of racemization and alpha-hydrogen exchange of the pyridoxal Schiff's bases of amino acidsTsai, M. D. ; Weintraub, H. J.; Byrn, S. R.; Chang, C.; Floss, H. G.Biochemistry 17, 3183-3188
2791978Conformational analysis of pyridoxal Schiff's bases. Nuclear magnetic resonance studies of the conformations about the C4-C4', Calpha-Cbeta, and N-Calpha bonds of the pyridoxal Schiff's bases of amino acidsTsai, M. D. ; Byrn, S. R.; Chang, C.; Floss, H. G.; Weintraub, H. J.Biochemistry 17, 3177-3182
2801978Stereochemistry and mechanism of reactions catalyzed by tryptophanase Escherichia coliVederas, J. C.; Schleicher, E.; Tsai, M. D. ; Floss, H. G.J Biol Chem 253, 5350-5354
2811978Stereochemistry and mechanism of reactions catalyzed by tryptophan synthetase and its beta2 subunitTsai, M. D. ; Schleicher, E.; Potts, R.; Skye, G. E.; Floss, H. G.J Biol Chem 253, 5344-5349
2821978Stereochemistry of the beta-cyanoalanine synthetase and S-alkylcysteine lyase reactionsTsai, M. D. ; Weaver, J.; Floss, H. G.; Conn, E. E.; Creveling, R. K.; Mazelis, M.Arch. Biochem. Biophys. 190, 553-559
2831976Conformational Analysis of Pyridoxal Amino Acid Schiffs BasesWeintraub, H. J. R.; Tsai, M. D. ; Byrn, S. R.; Chang, C. J.; Floss, H. G.International Journal of Quantum Chemistry 10(S3), 99-105
2841975Dye-sensitized Photooxidation of a-TerpineolCheng, Y. S.; Tsai, M. D. ; Fang, J. M.; Hsu, S. S.Chemistry (The Chinese Chem. Soc., Taiwan, China) 1, 8-11
2851974Air Oxidation of a-TerpineolTsai, M. D. ; Cheng, Y. S.Journal of the Chinese Chemical Society 21, 149-155
2861972Terpenes and Sterols of Cunninghamia KonishiiCheng, Y. S.; Tsai, M. D. Phytochemistry 11, 2108-2109
287-How a half-sized DNA polymerase catalyzes non-Watson-Crick dG:dGTP incorporationWen-Jin Wu; Mei-I Su; Sandeep Kumar; Ming-Chuan Chad Chen; Chun-Wei Eric Wang; Ming-Daw Tsai