| Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
| 1 | 2024 | 01.故院長講座. 吳大猷院長科普講座「見證奈米大小的酵素在奈秒內修復受損的DNA」 | 蔡明道 | | | | |
| 2 | 2018 | 01.故院長講座. 錢思亮院長講座「蛋白質結構的發展和最近的突破」 | 蔡明道 | | | | |
| 3 | 2017 | Aurora A and NF-κB Survival Pathway Drive Chemoresistance in Acute Myeloid Leukemia via the TRAF-Interacting Protein TIFA | Tong-You W. Wei; Pei-Yu Wu; Ting-Jung Wu; Hsinan Hou; Wen-Chien Chou; Chieh-Lin Teng; Chih-Ru Lin; Jou-May M. Chen; Ting-Yang Lin; Hsiang-Chun Su; Chia-Chi F. Huang; Chang-Tze R. Yu; shih-lan Hsu; Hwei-Fang Tien; Ming-Daw Tsai | Cancer Research 77(2), 494-508 | | | |
| 4 | 2016 | TIFA as a Crucial Mediator for NLRP3 Inflammasome | Ting-Yang Lin; Tong-You Wade Wei; Shuai Li; Shen-Chih Wang; Ming He; Marcy Martin; Jiao Zhang; Tzu-Pin Shentu; Han Xiao; Jian Kang; Kuei-Chun Wang; Zhen Chen; Shu Chien; Ming-Daw Tsai ; John Y-J. Shyy | PNAS 133(52), 15078-15083 | | | |
| 5 | 2015 | A Ribonuclease Coordinates siRNA Amplification and mRNA Cleavage during RNAi. | Hsin-Yue Tsai; Chun-Chieh G. Chen; Darryl Conte Jr; James J Moresco; Daniel A. Chaves; Shohei Mitani; John R. Yates III; Ming-Daw Tsai ; Craig C. Mello | Cell 160(3), 407-419 | | | |
| 6 | 2015 | Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses. | Weng, JH; Hsieh, YC; Huang, CC; Wei, TY; Lim, LH; Chen, YH; Ho, MR ; Wang, I; Huang, KF ; Chen, CJ; Tsai, MD | Biochemistry 54(40), 6219-6229 | | | |
| 7 | 2014 | PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase. | Zih-Jie Shen; Pang-Hung Hsu; Yu-Tai Su; Chia-Wei Yang; Li Kao; Shun-Fu Tseng; Ming-Daw Tsai ; Shu-Chun Teng | Nature Communications 5, 5312 | | | |
| 8 | 2014 | Ultrafast water dynamics at the interface of polymerase-DNA binding complex. | Yi Yang; Yangzhong Qin; Qing Ding; Marina Bakhtina; Lijuan Wang; Ming-Daw Tsai ; Dongping Zhong | Biochemistry 53, 5405-5413 | | | |
| 9 | 2014 | Multiple complexes of long-aliphatic N-acyltransferases led to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics effectively killing VRE. | Lyu, Syue-Yi; Liu, Yu-Chen; Chang, Chin-Yuan; Huang, Chuen-Jiuan; Chiu, Ya-Huang; Huang, Chun-Man; Hsu, Ning-Shian; Lin, Kuan-Hung; Wu, Chang-Jer; Tsai, Ming-Daw ; Li, Tsung-Lin | J. Am. Chem. Soc. 136, 10989-10995 | | | |
| 10 | 2013 | Protein-phosphoprotein complexes in DNA damage and cancer signaling | Tsai, Ming-Daw | | | | |
| 11 | 2013 | Protein-phosphorylation Complexes in DNA Damage and Cancer Signaling | Tsai, Ming-Daw | | | | |
| 12 | 2013 | Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis | Yu-Ching Teng; Cheng-Feng Lee; Ying-Shiuan Li; Yi-Ren Chen; Pei-Wen Hsiao; Meng-Yu Chan; Feng-Mao Lin; Hsien-Da Huang; Yen-Ting Chen; Yung-Ming Jeng; Qin Yan; Ming-Daw Tsai ; Li-Jung Juan | Cancer Research 73(15), 4711-4721 | | | |
| 13 | 2013 | Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response | Hsieh, YL; Kuo, HY; Chang, CC; Naik, MT; Liao, PH; Ho, CC; Huang, TC; Jeng, JC; Hsu, PH; Tsai, MD ; Huang, TH; Shih, HM | EMBO JOURNAL 32(6), 791-804 | | | |
| 14 | 2013 | Reversible Acetylation Regulates Salt-Inducible Kinase (SIK2) and Its Function in Autophagy | Yang, Fu-Chia; Tan, Bertrand Chin-Ming; Chen, Wei-Hao; Lin, Ya-Huei; Huang, Jing-Yi; Chang, Hsin-Yun; Sun, Hui-Yu; Hsu, Pang-Hung; Liou, Gunn-Guang; Shen, C. -K. James; Chang, Ching-Jin; Han, Chau-Chung ; Tsai, Ming-Daw ; Lee, Sheng-Chung | JOURNAL OF BIOLOGICAL CHEMISTRY 288(9), 6227-6237 | | | |
| 15 | 2012 | Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease. | Wei, PC; Hsieh, YH; Su, MI; Jiang, XJ; Hsu, PH; Lo, WT; Weng, JY; Jeng, YM; Wang, JM; Chen, PL; Chang, YC; Lee, KF; Tsai, MD ; Shew, JY; Lee, WH | Molecular cell 48(5), 747-59 | | | |
| 16 | 2012 | Enzyme Mechanisms – from in vitro to in vivo | Tsai, Ming-Daw | | | | |
| 17 | 2012 | How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53 | Tsai, Ming-Daw | | | | |
| 18 | 2012 | How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53 | Tsai, Ming-Daw | | | | |
| 19 | 2012 | How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53 | Tsai, Ming-Daw | | | | |
| 20 | 2012 | Intermolecular Binding between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF-κB Activation | Huang, CC; Weng, JH; Wei, TY; Wu, PY; Hsu, PH; Chen, YH; Wang, SC; Qin, D; Hung, CC ; Chen, ST ; Wang, AH ; Shyy, JY; Tsai, MD | Molecular and cellular biology 32(14), 2664-2673 | | | |
| 21 | 2012 | SUMOylation of Blimp‐1 is critical for plasma cell differentiation | Ying, H. -Y.; Su, S. -T.; Hsu, P. -H.; Chang, C. -C.; Lin, I-Y.; Tseng, Y. -H.; Tsai, M. -D. ; Shih, H. -M. ; Lin, K. -I | EMBO reports 13(7), 631-637 | | | |
| 22 | 2012 | A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase | Tsai, Ming-Daw | | | | |
| 23 | 2012 | Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68 | Wu, HH; Wu, PY; Huang, KF ; Kao, YY; Tsai, MD | Biochemistry 51(2), 575-577 | | | |
| 24 | 2012 | Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide | Lin, TL; Yang, FL; Yang, AS; Peng, HP; Li, TL ; Tsai, MD ; Wu, SH ; Wang, JT | PLoS One 7(10), e46783 | | | |
| 25 | 2011 | Kinetic mechanism of active site assembly and chemical catalysis of DNA Polymerase β | Balbo, PB; Wang, EC; Tsai, MD | Biochemistry 50(45), 9865-9875 | | | |
| 26 | 2011 | Protein kinase A-mediated serine 35 phosphorylation dissociates histone H1.4 from mitotic chromosome. | Chu, CS; Hsu, PH; Lo, PW; Scheer, E; Tora, L; Tsai, HJ; Tsai, MD ; Juan, LJ | Journal of biological chemistry 286(41), 35843-35851 | | | |
| 27 | 2011 | How some error prone DNA polymerases overcome Watson-Crick base pairing | Tsai, Ming-Daw | | | | |
| 28 | 2011 | FHA, a signaling domain with diverse specificities and functions | Tsai, Ming-Daw | | | | |
| 29 | 2011 | The C-terminus of histone H2B is involved in chromatin compaction specifically at telomeres, independently of its monoubiquitylation at lysine 123 | Wang, CY; Hua, CY; Hsu, HE; Hsu, CL; Tseng, HY; Wright, DE; Hsu, PH; Jen, CH; Lin, CY; Wu, MY; Tsai, MD ; Kao, CF | PloS one 6(7), e22209 | | | |
| 30 | 2011 | Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer | Li, J; Poi, MJ; Tsai, MD | BIOCHEMISTRY 50 (25), 5566–5582 | | | |
| 31 | 2011 | The histone H3K36 demethylase Rph1/KDM4 regulates the expression of the photoreactivation gene PHR1 | Liang, Chung-Yi; Hsu, Pang-Hung; Chou, Dai-Fang; Pan, Chao-Yu; Wang, Long-Chi; Huang, Wei-Chieh; Tsai, Ming-Daw ; Lo, Wan-Sheng | Nucleic Acids Research 39(10), 4151-4165 | | | |
| 32 | 2011 | Interception of teicoplanin oxidation intermediates yields new antimicrobial scaffolds | Liu, Y. C.; Li, Y. S.; Lyu, S. Y.; Hsu, L. J.; Chen, Y. H.; Huang, Y. T.; Chan, H. C.; Huang, C. J.; Chen, G. H.; Chou, C. C.; Tsai, M. D. ; Li, T. L. | Nature chemical biology 7(5), 304-309 | | | |
| 33 | 2011 | Regioselective deacetylation based on teicoplanin-complexed Orf2* crystal structures. | Chan, HC; Huang, YT; Lyu, SY; Huang, CJ; Li, YS; Liu, YC; Chou, CC; Tsai, MD ; Li, TL | Molecular bioSystems 7(4), 1224-1231 | | | |
| 34 | 2011 | Structural and Mechanistic Bases for the G:G Specificity of ASFV DNA Polymerase X | Tsai, Ming-Daw | | | | |
| 35 | 2011 | Functions of Some Capsular Polysaccharide Biosynthetic Genes in Klebsiella pneumoniae NTUH K-2044 | Ho, JY; Lin, TL; Li, CY; Lee, A; Cheng, AN; Chen, MC; Wu, SH ; Wang, JT; Li, TL ; Tsai, MD | PLoS One 6(7), e21664 | | | |
| 36 | 2011 | Phosphorylation of NuSAP by Cdk1 regulates its interaction with microtubules in mitosis. | Chou, HY; Wang, TH; Lee, SC; Hsu, PH; Tsai, MD ; Chang, CL; Jeng, YM | CELL CYCLE 10(23), 4083-4089 | | | |
| 37 | 2011 | E339…R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors | Shen, Y. -F.; Chen, Y. -H.; Chu, S. -Y.; Lin, M. -I.; Hsu, H. -T.; Wu, P. -Y.; Wu, C. -J.; Liu, H. -W.; Lin, F. -Y.; Lin, G.; Hsu, P. -H.; Yang, A. -S. ; Cheng, Y. -S. E.; Wu, Y. -T.; Wong, C. -H. ; Tsai, M. -D. | Proceedings of the National Academy of Sciences of the United States of America 108(40), 16515-16520 | | | |
| 38 | 2010 | Structure and Mechanism of Mutagenic DNA Polymerase X | Su, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw | | | | |
| 39 | 2010 | A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase Cascade | Tsai, Ming-Daw | | | | |
| 40 | 2010 | Mechanism of High-Fidelity DNA Polymerase β and Low-Fidelity DNA Polymerase X | Tsai, Ming-Daw | | | | |
| 41 | 2010 | Counting the Phosphates of a Phosphorylation Site Cluster | Tsai, Ming-Daw | | | | |
| 42 | 2010 | Protein-Protein Interactions as Potential Drug Targets | Tsai, Ming-Daw | | | | |
| 43 | 2010 | 8.10 - Catalytic Mechanism of DNA Polymerases | Roettger, Michelle P.; Bakhtina, Marina; Kumar, Sandeep; Tsai, Ming-Daw | Comprehensive Natural Products II: Chemistry and Biology (USA : Elsevier Oxford) | | | |
| 44 | 2010 | Nonhydrolyzable Analogs of Phosphatidylinositol as Ligands of Phospholipases C. | Mihai, C; Yue, XJ; Zhao, L; Kravchuk, A; Tsai, MD ; Bruzik, KS | New J. Chem. 34, 925-933 | | | |
| 45 | 2010 | Global Analysis of Modifications of Human BK Virus Structural proteins by Mass Spectrometry | Fang, CY; Chen, HY; Wang, M; Chen, PL; Chang, CF; Chen, LS; Shen, CH; Ou, WC; Tsai, MD ; Hsu, PH; Chang, D | VIROLOGY 402(1), 164-176 | | | |
| 46 | 2010 | Database Search Algorithm for Identification of Intact Cross-Links in Proteins and Peptides Using Tandem Mass Spectrometry | Xu, H; Hsu, PH; Zhang, L; Tsai, MD ; Freitas, MA | JOURNAL OF PROTEOME RESEARCH 9(7), 3384-3393 | | | |
| 47 | 2010 | Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins | Guo, Y; Yuan, C; Tian, F; Huang, K; Weghorst, CM; Tsai, MD ; Li, J | J. Mol. Biol. 399(1),168-181 | | | |
| 48 | 2010 | Unique Catalytic Mechanism of Phosphatidylinositol-Specific Phospholipase C from Streptomyces antibioticus | Bai, C; Zhao, L; Tsai, MD ; Bruzik, KS | J. Am. Chem. Soc. 132(4), 1210–1211 | | | |
| 49 | 2010 | alpha-Helical burst on the folding pathway of FHA domains from Rad53 and Ki67 | Matsumura, Y; Shinjo, M; Mahajan, A; Tsai, MD ; Kihara, H | Biochimie 92(8), 1031-1039 | | | |
| 50 | 2010 | Unambiguous Determination of Isobaric Histone Modifications by Reverse-Phase Retention Time and High-Mass Accuracy | Yang, L; Tu, S; Ren, C; Bulloch, EM; Liao, CL; Tsai, MD ; Freitas, MA | Anal. Biochem. 396(1),13-22 | | | |
| 51 | 2010 | JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells | Lee, T. L.; Shyu, Y. C.; Hsu, P. C.; Wen, S. C.; Hsiao, W. Y.; Chang, C. W.; Tsai, M. D. ; Shen, C. -K. J. | Proceedings of the national academy of sciences of the United States of America 107(1), 52-57 | | | |
| 52 | 2010 | High-throughput Identification of Compounds Targeting Influenza RNA-dependent RNA Polymerase Activity | Su, C. -Y.; Cheng, T. -J. R.; Lin, M. -I.; Wang, S. -Y.; Huang, W. -I.; Lin-Chu, S. -Y.; Chen, Y. -H.; Wu, C. -Y.; Lai, M. M. C. ; Cheng, W. -C.; Wu, Y. -T.; Tsai, M. -D. ; Cheng, Y. -S. E.; Wong, C. -H. | Proceedings of the National Academy of Sciences of the United States of America 107(45), 19151-19156 | | | |
| 53 | 2009 | An Enzymologist's Approach to Histone Demethylases | Tsai, Ming-Daw | | | | |
| 54 | 2009 | Structure and Mechanism of Mutagenic DNA Polymerase X | Su, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw | | | | |
| 55 | 2009 | Structure and Mechanism of Mutagenic DNA Polymerase X | Su, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw | | | | |
| 56 | 2009 | Structure and Mechanism of Mutagenic DNA Polymerase X | Su, Mei-I; Wu, Wen-Jin; Kumar, Sandeep; Tsai, Ming-Daw | | | | |
| 57 | 2009 | A Phosphate-Counting Mechanism for Sequential Activiation of a Checkpoint Kinase Cascade | Lee, Hyun; Yuan, Chunhua; Chen, Eric S. -W.; Mahajan, Anjali; Hammet, Andrew; Heierhorst, Jörg; Tsai, Ming-Daw | | | | |
| 58 | 2009 | Protein-phosphoprotein interactions of phosphothreonine-specific FHA domains | Tsai, Ming-Daw | | | | |
| 59 | 2009 | Molecular Interactions of Biophosphates – from Catalysis to Signaling | Tsai, Ming-Daw | | | | |
| 60 | 2009 | FHA, a signaling domain with diverse specificities | Tsai, Ming-Daw | | | | |
| 61 | 2009 | Contribution of the Reverse Rate of the Conformational Step to Polymerase beta Fidelity | Bakhtina, M; Roettger, MP; Tsai, MD | Biochemistry 48(14), 3197-3208 | | | |
| 62 | 2009 | AMP-Activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser-633 | Chen, Z; Peng, IC; Sun, W; Su, MI; Hsu, PH; Fu, Y; Zhu, Y; DeFea, K; Pan, S; Tsai, MD ; Shyy, JY | CIRCULATION RESEARCH 104(4), 496-505 | | | |
| 63 | 2009 | Humoral immunity against capsule polysaccharide protects the host from magA+ Klebsiella pneumoniae-induced lethal disease by evading Toll-like receptor 4 signaling | Wu, MF; Yang, CY; Lin, TL; Wang, JT; Yang, FL; Wu, SH ; Hu, BS; Chou, TY; Tsai, MD ; Lin, CH; Hsieh, SL | Infection and immunity 77(2), 615-621 | | | |
| 64 | 2009 | Trans-Cyclization of Phosphatidylinositol Catalyzed by Phospholipase C from Streptomyces antibioticus | Bai C; Zhao, L; Rebecchi, M; Tsai, MD ; Bruzik, KS | J. Am. Chem. Soc. 131(24), 8362-8363 | | | |
| 65 | 2009 | Comparisons of the Conformational Stability of Cyclin-dependent Kinase (CDK) 4-Interacting Ankyrin Repeat (AR) Proteins | Guo, Y; Mahajan, A; Yuan, C; Joo, SH; Weghorst, CM; Tsai, MD ; Li, J | Biochemistry 48(19), 4050-4062 | | | |
| 66 | 2008 | The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif | Tu, S; Teng, YC; Yuan, C; Wu, YT ; Chan, MY; Cheng, AN; Lin, PH; Juan, LJ ; Tsai, MD | Nature Structural & Molecular Biology 15(4), 419-421 | | | |
| 67 | 2008 | Structure and Function of the Phosphothreonine-Specific FHA Domain | Mahajan, A; Yuan, C; Lee, H; Chen, ES; Wu, PY; Tsai, MD | Science Signaling 1(51), re12. | | | |
| 68 | 2008 | Mismatched and Matched dNTP Incorporation by DNA Polymerase β Proceed via Analogous Kinetic Pathways | Roettger, M. P.; Bakhtina, M.; Tsai, M. D. | Biochemistry 47, 9718-9727 | | | |
| 69 | 2008 | Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. | Lee, H; Yuan, C; Hammet, A; Mahajan, A; Chen, ES; Wu, MR; Su, MI; Heierhorst, J; Tsai, MD | Mol. Cell 30, 767-778 | | | |
| 70 | 2008 | Altered Order of Substrate Binding by DNA Polymerase X from African Swine Fever Virus | Kumar, S; Bakhtina, M; Tsai, MD | Biochemistry 47, 7875-7887 | | | |
| 71 | 2008 | Solution structures of 2 : 1 and 1 : 1 DNA polymerase-DNA complexes probed by ultracentrifugation and small-angle X-ray scattering. | Tang, Kuo-Hsiang; Niebuhr, Marc; Aulabaugh, Ann; Tsai, Ming-Daw | Nucleic Acids Res 36, 849-860 | | | |
| 72 | 2008 | Mismatched dNTP Incorporation by DNA Polymerase β Does Not Proceed via Globally Different Conformational Pathways | Tang, Kuo-Hsiang; Niebuhr, Marc; Tung, Chang-Shung; Chan, Hsiu-chien; Chou, Chia-Cheng; Tsai, Ming-Daw | Nucleic Acids Res 36, 2948-2957 | | | |
| 73 | 2008 | Structure and Function of 2:1 DNA Polymerase•DNA Complexes | Tang, Kuo-Hsiang; Tsai, Ming-Daw | JOURNAL OF CELLULAR PHYSIOLOGY 216, 315-320 | | | |
| 74 | 2007 | Identification of in Vivo Phosphorylation Sites and Their Functional Significance in the Sodium Iodide Symporter | Vadysirisack, DD; Chen, ES; Zhang, Z; Tsai, MD ; Chang, GD; Jhiang, SM | J. Biol. Chem. 282, 36820-8 | | | |
| 75 | 2007 | Identification of Histone Demethylases in Saccharomyces cerevisiae | Tu, S.; Bulloch, E. M. M.; Yang, L.; Ren, C.; Huang, W. -C.; Hsu, P. -H.; Chen, C. -H.; Liao, C. -L.; Yu, H. -M. ; Lo, Wan-Sheng ; Freitas, M. A.; Tsai, M. D. | J. Biol. Chem 282(19), 14262-14271 | | | |
| 76 | 2007 | Human p16γ, a novel transcriptional variant of p16INK4A, coexpresses with p16INK4A in cancer cells and inhibits cell-cycle progression | Lin, Y. C.; Diccianni, M. B.; Kim, Y.; Lin, H. H.; Lee, C. H.; Lin, R. J.; Joo, S. H.; Li, J.; Chuang, T. J.; Yang, A. S. ; Kuo, H. H.; Tsai, M. D. ; Yu, A. L. | Oncogene 26(49), 7017-7027 | | | |
| 77 | 2007 | Human DNA Ligase IV and the Ligase IV/XRCC4 Complex: Analysis of Nick Ligation Fidelity | Wang, Yu; Lamarche, Brandon J.; Tsai, Ming-Daw | Biochemistry 46, 4962-4976 | | | |
| 78 | 2007 | Investigation of the conformational states of Wzz and the Wzz.O-antigen complex under near-physiological conditions. | Tang, Kuo-Hsiang; Guo, Hongjie; Yi, Wen; Tsai, Ming-Daw ; Wang, Peng George | Biochemistry 46, 11744-11752 | | | |
| 79 | 2007 | A Unique FMN-linked Primary Alcohol Oxidase for Glycopeptide A40926 Maturation | Li, Yi-Shan; Ho, Jin-Yuan; Huang, Chia-Chi; Lyu, Syue-Yi; Lee, Chun-Yen; Huang, Yu-Ting; Wu, Chang-Jer; Chan, Hsiu-Chien; Huang, Chuan-Jiuan; Hsu, Ning-Shian; Tsai, Ming-Daw ; Li, Tsung-Lin | J. Am. Chem. Soc 129, 13384-13385 | | | |
| 80 | 2007 | A Unified Kinetic Mechanism Applicable to Multiple DNA Polymerases | Bakhtina, Marina; Roettger, Michelle P.; Kumar, Sandeep; Tsai, Ming-Daw | Biochemistry 46, 5463-5472 | | | |
| 81 | 2007 | Dissection of Protein-Protein Interaction and CDK4 Inhibition in the Oncogenic versus Tumor Suppressing Functions of Gankyrin and P16 | Mahajan, Anjali; Guo, Yi; Weghorst, Christopher M.; Yuan, Chunhua; Tsai, Ming-Daw ; Li, Junan | J. Mol. Biol 373, 990-1005 | | | |
| 82 | 2007 | Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus. | Lamarche, B. J.; Kumar, S.; Tsai, M. D. | Biochemistry 46, 3814-3825 | | | |
| 83 | 2006 | Mechanistic comparison of high-fidelity and error-prone DNA polymerases and ligases involved in DNA repair. | Showalter, AK; Lamarche, BJ; Bakhtina, M; Su, MI; Tang, KH; Tsai, MD | Chemical reviews 106(2), 340-60 | | | |
| 84 | 2006 | Third Calcium Ion Found in an Inhibitor Bound Phospholipase A2 | Sekar, K; Gayathri, D; Velmurugan, D; Jeyakanthan, J; Yamane, T; Poi, MJ; Tsai, MD | ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY D62, 392-397 | | | |
| 85 | 2006 | Contributions of an Endonuclease IV Homolog to DNA Repair in the African Swine Fever Virus | Lamarche, BJ; Tsai, MD | BIOCHEMISTRY 45, 2790-2803 | | | |
| 86 | 2006 | Ankyrin Repeat: A Unique Motif Mediating Protein--Protein Interactions | Li, J; Mahajan, A; Tsai, MD | Biochemistry 45, 15168-15178 | | | |
| 87 | 2006 | Atomic Resolution Structure of the Double Mutant (K53,56M) of Bovine Pancreatic Phospholipase A2 | Sekar, K; Yogavel, M; Gayathri, D; Velmurugan, D; Krishna, R; Poi, MJ; Dauter, Z; Dauter, M; Tsai, MD | Acta Crystallographica Section F-Structural Biology and Crystallization Communications F62, 1-5 | | | |
| 88 | 2006 | Suggestive evidence for the involvement of the second calcium and surface loop in interfacial binding: monoclinic and trigonal crystal structures of a quadruple mutant of phospholipase A2. | Sekar, K; Yogavel, M; Kanaujia, SP; Sharma, A; Velmurugan, D; Poi, MJ; Dauter, Z; Tsai, MD | ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 62(Pt 7), 717-24 | | | |
| 89 | 2006 | Glycopeptide biosynthesis: Dbv21/Orf2 from dbv/tcp gene clusters are N-Ac-Glm teicoplanin pseudoaglycone deacetylases and Orf15 from cep gene cluster is a Glc-1-P thymidyltransferase. | Ho, J. Y.; Huang, Y. T.; Wu, C. J.; Li, Y. S.; Tsai, M. D. ; Li, T. L. | J. Am. Chem. Soc 128, 13694-13695 | | | |
| 90 | 2006 | ASFV DNA polymerse X is extremely error-prone under diverse assay conditions and within multiple DNA sequence contexts. | Lamarche, B. J.; Kumar, S.; Tsai, M. D. | Biochemistry 45, 14826-14833 | | | |
| 91 | 2005 | Dissection of CDK4-binding and Transactivation Activities of p34SEI-1 and Comparison between Functions of p34SEI-1 and p16INK4 | Li, J; Muscarella, P; Joo, SH; Knobloch, TJ; Melvin, WS; Weghorst, CM; Tsai, MD | Biochemistry 44, 13246-13256 | | | |
| 92 | 2005 | FHA Domain−Ligand Interactions: Importance of Integrating Chemical and Biological Approaches | Mahajan, A; Yuan, C; Pike, BL; Heierhorst, J; Chang, CF ; Tsai, MD | Journal of the American Chemical Society 127(42), 14572-14573 | | | |
| 93 | 2005 | Sequential Phosphorylation and Multisite Interactions Characterize Specific Target Recognition by the FHA Domain of Ki-67 | Byeon, IJ; Li, H; Song, H; Gronenborn, AM; Tsai, MD | Nature Structural and Molecular Biology 12, 987-993 | | | |
| 94 | 2005 | X-ray structure of the R69D phosphatidylinositol-specific phospholipase C enzyme: insight into the role of calcium and surrounding amino acids in active site geometry and catalysis | Apiyo, D; Zhao, L; Tsai, MD ; Selby, TL | Biochemistry 44, 9980-9989 | | | |
| 95 | 2005 | Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta. | Bakhtina, M; Lee, S; Wang, Y; Dunlap, C; Lamarche, B; Tsai, MD | Biochemistry 44, 5177-5187 | | | |
| 96 | 2005 | Unusual Four-bond Secondary H/D Isotope Effect Supports a Short-Strong Hydrogen Bond between Phospholipase A2 and a Transition State Analog Inhibitor | Yuan, C. H.; Tu, S.; Gelb, Michael H.; Tsai, M. D. | Biochemistry 44, 4748-4754 | | | |
| 97 | 2005 | An Error-Prone Viral DNA Ligase | Lamarche, B.; Showalter, A.; Tsai, M. D. | Biochemistry 44, 8408-8417 | | | |
| 98 | 2005 | Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2 | Sekar, K; Rajakannan, V; Gayathri, D; Velmurugan, D; Poi, MJ; Dauter, M; Dauter, Z; Tsai, MD | Acta Crystallograph Sect F Struct Biol Cryst Commun F61, 3-7 | | | |
| 99 | 2004 | The nuclear protein p34(SEI-1) regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner | Li, J; Melvin, WS; Tsai, MD ; Muscarella, P | Biochemistry 43, 4394-4399 | | | |
| 100 | 2004 | Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship | Yuan, C; Li, J; Mahajan, A; Poi, MJ; Byeon, IJ; Tsai, MD | Biochemistry 43, 12152-12161 | | | |
| 101 | 2004 | The ligand specificity of yeast Rad53 FHA domains at the +3 position is determined by nonconserved residues | Yongkiettrakul, S; Byeon, IJ; Tsai, MD | Biochemistry 43, 3862-3869 | | | |
| 102 | 2004 | The catalytic role of aspartate in a short strong hydrogen bond of the Asp274-His32 catalytic dyad in phosphatidylinositol-specific phospholipase C can be substituted by a chloride ion | Zhao, L; Liao, H; Tsai, MD | J Biol Chem 279, 31995-32000 | | | |
| 103 | 2004 | Gene Library Synthesis by Structure-based Combinatorial Protein Engineering (SCOPE) | O’Maille, P. E.; Tsai, M. D. ; Noel, J. P. | Methods in Enzymology 388, 75-91 | | | |
| 104 | 2004 | Enzyme Reaction Mechanisms: Stereochemistry | Tsai, M. D. ; Zhao, L.; Lamarche, B. | Encyclopedia in Biological Chemistry 2, 45-50 | | | |
| 105 | 2004 | Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae | Pike, B. L.; Yongkiettrakul, S.; Tsai, M. D. ; Heierhorst, J. | Mol Cell Biol 24, 2779-2788 | | | |
| 106 | 2004 | Sequential phosphorylation of hNIFK by CDC2/cyclin B and GSK3 kinases in vitro leads to recognition by Ki67 FHA domain and suggests Ki67 is involved in cell cycle control | Li, H.; Song, H.; Tsai, M. D. | (Submitted) | | | |
| 107 | 2004 | Frequent p16INK4A/CDKN2A alterations in chemically induced Syrian golden hamster pancreatic tumors | Li, J; Weghorst, CM; Tsutsumi, M; Poi, MJ; Knobloch, TJ; Casto, BC; Melvin, WS; Tsai, MD ; Muscarella, P | Carcinogenesis 25, 263-268 | | | |
| 108 | 2004 | Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions | Li, H; Byeon, IJ; Ju, Y; Tsai, MD | J Mol Biol 335, 371-381 | | | |
| 109 | 2003 | Biocatalysis and Biotransformation Enzymology in the Genomic Era – Editorial Overview | Begley, TP; Tsai, MD | Curr. Opin. Chem. Biol 7, 228-229 | | | |
| 110 | 2003 | An NF-kappaB-specific inhibitor, IkappaBalpha, binds to and inhibits cyclin-dependent kinase 4 | Li, J; Joo, SH; Tsai, MD | Biochemistry 42, 13476-13483 | | | |
| 111 | 2003 | Direct binding of the N-terminus of HTLV-1 tax oncoprotein to cyclin-dependent kinase 4 is a dominant path to stimulate the kinase activity | Li, J; Li, H; Tsai, MD | Biochemistry 42, 6921-6928 | | | |
| 112 | 2003 | A novel calcium-dependent bacterial phosphatidylinositol-specific phospholipase C displaying unprecedented magnitudes of thio effect, inverse thio effect, and stereoselectivity | Zhao, L; Liu, Y; Bruzik, KS; Tsai, MD | J Am Chem Soc 125, 22-23 | | | |
| 113 | 2003 | Crystal structures of the free and anisic acid bound triple mutant of phospholipase A2 | Sekar, K; Vaijayanthi Mala, S; Yogavel, M; Velmurugan, D; Poi, MJ; Vishwanath, BS; Gowda, TV; Jeyaprakash, AA; Tsai, MD | J Mol Biol 333, 367-376 | | | |
| 114 | 2003 | Interaction of monodisperse anionic amphiphiles with the i-face of secreted phospholipase A2 | Yu, B. Z.; Apitz-Castro, R.; Tsai, M. D. ; Jain, M. K. | Biochemistry 42, 6293-6301 | | | |
| 115 | 2003 | A low-barrier hydrogen bond between histidine of secreted phospholipase A2 and a transition state analog inhibitor | Poi, M. J.; Tomaszewski, J. W.; Yuan, C.; Dunlap, C. A.; Andersen, N. H.; Gelb, M. H.; Tsai, M. D. | J Mol Biol 329, 997-1009 | | | |
| 116 | 2003 | Application of Bronsted-type LFER in the study of the phospholipase C mechanism | Mihai, C.; Kravchuk, A. V.; Tsai, M. D. ; Bruzik, K. S. | J Am Chem Soc 125, 3236-3242 | | | |
| 117 | 2003 | Engineering a catalytic metal binding site into a calcium-independent phosphatidylinositol-specific phospholipase C leads to enhanced stereoselectivity | Kravchuk, A. V.; Zhao, L.; Bruzik, K. S.; Tsai, M. D. | Biochemistry 42, 2422-2430 | | | |
| 118 | 2003 | Expression and characterization of Syrian golden hamster p16, a homologue of human tumor suppressor p16 INK4A | Li, J; Qin, D; Knobloch, TJ; Tsai, MD ; Weghorst, CM; Melvin, WS; Muscarella, P | Biochem Biophys Res Commun 304, 241-247 | | | |
| 119 | 2003 | Identification of potential binding sites for the FHA domain of human Chk2 by in vitro binding studies | Qin, D; Lee, H; Yuan, C; Ju, Y; Tsai, MD | Biochem Biophys Res Commun 311, 803-808 | | | |
| 120 | 2002 | Observation of additional calcium ion in the crystal structure of the triple mutant K56,120,121M of bovine pancreatic phospholipase A2 | Rajakannan, V; Yogavel, M; Poi, MJ; Jeyaprakash, AA; Jeyakanthan, J; Velmurugan, D; Tsai, MD ; Sekar, K | J Mol Biol 324, 755-762 | | | |
| 121 | 2002 | Novel insights into the INK4-CDK4/6-Rb pathway: counter action of gankyrin against INK4 proteins regulates the CDK4-mediated phosphorylation of Rb | Li, J; Tsai, MD | Biochemistry 41, 3977-3983 | | | |
| 122 | 2002 | A reexamination of the nucleotide incorporation fidelity of DNA polymerases | Showalter, A. K.; Tsai, M. D. | Biochemistry 41, 10571-10576 | | | |
| 123 | 2002 | FHA: a signal transduction domain with diverse specificity and function | Tsai, M. D. | Structure 10, 887-888 | | | |
| 124 | 2002 | Structure-based combinatorial protein engineering (SCOPE) | O’Maille, P. E.; Bakhtina, M.; Tsai, M. D. | J Mol Biol 321, 677-691 | | | |
| 125 | 2002 | Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta | Dunlap, C. A.; Tsai, M. D. | Biochemistry 41, 11226-11235 | | | |
| 126 | 2001 | “Learning Is a Lifelong Process” in Reflections on Multiliterate Lives | Diane Dewhurst Belcher; Ulla Connor Eds.; Tsai, Ming-Daw | Clevedon, England ; Buffalo, N.Y. : Multilingual Matters, 135-140 | | | |
| 127 | 2001 | DNA polymerase beta: pre-steady-state kinetic analyses of dATP alpha S stereoselectivity and alteration of the stereoselectivity by various metal ions and by site-directed mutagenesis | Liu, J; Tsai, MD | Biochemistry 40, 9014-9022 | | | |
| 128 | 2001 | Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53 | Yuan, C; Yongkiettrakul, S; Byeon, IJ; Zhou, S; Tsai, MD | J Mol Biol 314, 563-575 | | | |
| 129 | 2001 | A DNA polymerase with specificity for five base pairs | Showalter, A. K.; Tsai, M. D. | J Am Chem Soc 123, 1776-1777 | | | |
| 130 | 2001 | Interfacial enzymology: the secreted phospholipase A(2)-paradigm | Berg, O. G.; Gelb, M. H.; Tsai, M. D. ; Jain, M. K. | Chem Rev 101, 2613-2654 | | | |
| 131 | 2001 | Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes | Arndt, J. W.; Gong, W.; Zhong, X.; Showalter, A. K.; Liu, J.; Dunlap, C. A.; Lin, Z.; Paxson, C.; Tsai, M. D. ; Chan, M. K. | Biochemistry 40, 5368-5375 | | | |
| 132 | 2001 | Somatic INK4a-ARF locus mutations: a significant mechanism of gene inactivation in squamous cell carcinomas of the head and neck | Poi, M. J.; Yen, T.; Li, J.; Song, H.; Lang, J. C.; Schuller, D. E.; Pearl, D. K.; Casto, B. C.; Tsai, M. D. ; Weghorst, C. M. | Molecular Carcinogenesis 30, 26-36 | | | |
| 133 | 2001 | Mechanism of phosphatidylinositol-specific phospholipase C: origin of unusually high nonbridging thio effects | Kravchuk, A. V.; Zhao, L.; Kubiak, R. J.; Bruzik, K. S.; Tsai, M. D. | Biochemistry 40, 5433-5439 | | | |
| 134 | 2001 | Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes | Byeon, I. J.; Yongkiettrakul, S.; Tsai, M. D. | J Mol Biol 314, 577-588 | | | |
| 135 | 2001 | Involvement of the Arg-Asp-His catalytic triad in enzymatic cleavage of the phosphodiester bond | Kubiak, R. J.; Yue, X.; Hondal, R. J.; Mihai, C.; Tsai, M. D. ; Bruzik, K. S. | Biochemistry 40, 5422-5432 | | | |
| 136 | 2001 | Solution structure of a viral DNA polymerase X and evidence for a mutagenic function | Showalter, A. K.; Byeon, I. J.; Su, M. I.; Tsai, M. D. | Nat Struct Biol 8, 942-946 | | | |
| 137 | 2000 | Kinetic Isotope Effects and Stereochemical Studies on a Ribonuclease Model: Hydrolysis Reactions of Uridine 3'-Nitrophenyl Phosphate | Hengge, AC; Bruzik, KS; Tobin, AE; Cleland, WW; Tsai, MD | BIOORGANIC CHEMISTRY 28, 119-133 | | | |
| 138 | 2000 | Structural basis of the anionic interface preference and kcat* activation of pancreatic phospholipase A2 | Yu, B. Z.; Poi, M. J.; Ramagopal, U. A.; Jain, R.; Ramakumar, S.; Berg, O. G.; Tsai, M. D. ; Sekar, K.; Jain, M. K. | Biochemistry 39, 12312-12323 | | | |
| 139 | 2000 | Tumor suppressor INK4: refinement of p16INK4A structure and determination of p15INK4B structure by comparative modeling and NMR data | Yuan, C; Selby, TL; Li, J; Byeon, IJ; Tsai, MD | Protein Sci 9, 1120-1128 | | | |
| 140 | 2000 | Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides | Wang, P; Byeon, IJ; Liao, H; Beebe, KD; Yongkiettrakul, S; Pei, D; Tsai, MD | J Mol Biol 302, 927-940 | | | |
| 141 | 2000 | Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9 | Liao, H; Yuan, C; Su, MI; Yongkiettrakul, S; Qin, D; Li, H; Byeon, IJ; Pei, D; Tsai, MD | J Mol Biol 304, 941-951 | | | |
| 142 | 2000 | Structure-Function Relationship of the INK4 Family of Tumor Suppressors | Li, J; Byeon, IJ; Poi, MJ; Ericson, K; Selby, T; O’Maille, P; Qin, D; Tsai, MD | In: DNA Alterations in Cancer: Genetic and Epigenetic Changes 71-84 | | | |
| 143 | 2000 | DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity | Kraynov, V. S.; Showalter, A. K.; Liu, J.; Zhong, X.; Tsai, M. D. | Biochemistry 39, 16008-16015 | | | |
| 144 | 2000 | Tumor suppressor INK4: quantitative structure-function analyses of p18INK4C as an inhibitor of cyclin-dependent kinase 4 | Li, J; Poi, MJ; Qin, D; Selby, TL; Byeon, IJ; Tsai, MD | Biochemistry 39, 649-657 | | | |
| 145 | 1999 | Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A | Li, J; Byeon, IJ; Ericson, K; Poi, MJ; O’Maille, P; Selby, T; Tsai, MD | Biochemistry 38, 2930-2940 | | | |
| 146 | 1999 | Nucleoside Monophosphate Kinases: Structure, Mechanism, and Substrate Specificity | Yan, H; Tsai, MD | Advances in Enzymology and Related Areas of Molecular Biology 73, 103-134 | | | |
| 147 | 1999 | Contributions of residues of pancreatic phospholipase A2 to interfacial binding, catalysis, and activation | Yu, BZ; Rogers, J; Tsai, MD ; Pidgeon, C; Jain, MK | Biochemistry 38, 4875-4884 | | | |
| 148 | 1999 | Pancreatic phospholipase A2: new views on old issues | Yuan, C; Tsai, MD | Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids 1441, 215-222 | | | |
| 149 | 1999 | Tumor suppressor INK4: comparisons of conformational properties between p16(INK4A) and p18(INK4C) | Yuan, C; Li, J; Selby, TL; Byeon, IJ; Tsai, MD | J Mol Biol 294, 201-211 | | | |
| 150 | 1999 | Identification of a novel catalytic triad with dual functions in enzymatic cleavage of the P-O bond | Kubiak, R. J.; Hondal, R. J.; Yue, X. J.; Tsai, M. D. ; Bruzik, K. S. | J Am Chem Soc 121, 488-489 | | | |
| 151 | 1999 | Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2 | Sekar, K; Biswas, R; Li, Y; Tsai, MD ; Sundaralingam, M | Acta Crystallographica Section D-Biological Crystallography 55, 443-447 | | | |
| 152 | 1999 | Structural analysis of phospholipase A2 from functional perspective. 1. Functionally relevant solution structure and roles of the hydrogen-bonding network | Yuan, C; Byeon, IJ; Li, Y; Tsai, MD | Biochemistry 38, 2909-2918 | | | |
| 153 | 1999 | Structural analysis of phospholipase A2 from functional perspective. 2. Characterization of a molten globule-like state induced by site-specific mutagenesis | Yuan, C; Byeon, IJ; Poi, MJ; Tsai, MD | Biochemistry 38, 2919-2929 | | | |
| 154 | 1999 | Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53 | Liao, H; Byeon, IJ; Tsai, MD | J Mol Biol 294, 1041-1049 | | | |
| 155 | 1998 | DNA polymerase beta. 5. Dissecting the functional roles of the two metal ions with Cr(III)dTTP | Zhong, X. J.; Patel, S. S.; Tsai, M. D. | J Am Chem Soc 120, 235-236 | | | |
| 156 | 1998 | Cationic residues 53 and 56 control the anion-induced interfacial k*cat activation of pancreatic phospholipase A2 | Rogers, J; Yu, BZ; Tsai, MD ; Berg, OG; Jain, MK | Biochemistry 37, 9549-9556 | | | |
| 157 | 1998 | 1.72 A resolution refinement of the trigonal form of bovine pancreatic phospholipase A2 | Sekar, K; Sekharudu, C; Tsai, MD ; Sundaralingam, M | Acta Crystallographica Section D-Biological Crystallography 54, 342-346 | | | |
| 158 | 1998 | DNA polymerase beta: effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes | Ahn, J; Kraynov, VS; Zhong, X; Werneburg, BG; Tsai, MD | Biochem J 331, 79-87 | | | |
| 159 | 1998 | Mechanism of phosphatidylinositol-specific phospholipase C: a unified view of the mechanism of catalysis | Hondal, R. J.; Zhao, Z.; Kravchuk, A. V.; Liao, H.; Riddle, S. R.; Yue, X.; Bruzik, K. S.; Tsai, M. D. | Biochemistry 37, 4568-4580 | | | |
| 160 | 1998 | Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4 | Byeon, I. J.; Li, J.; Ericson, K.; Selby, T. L.; Tevelev, A.; Kim, H. J.; O’Maille, P.; Tsai, M. D. | Mol Cell 1, 421-431 | | | |
| 161 | 1998 | Mechanism of PI-Specific Phospholipase C. 5. Revealed by Protein Engineering and Phosphorothioate Analogs of Phosphatidylinositol | Hondal, R. J.; Zhao, Z.; Kravchuk, A. V.; Liao, H.; Riddle, S. R.; Bruzik, K. S.; Tsai, M. D. | In: Phosphoinositides: Chemistry, Biochemistry and Biomedical Applications 718, 109-120 | | | |
| 162 | 1998 | Structure of the complex of bovine pancreatic phospholipase A2 with a transition-state analogue | Sekar, K; Kumar, A; Liu, X; Tsai, MD ; Gelb, MH; Sundaralingam, M | Acta Crystallographica Section D-Biological Crystallography 54, 334-341 | | | |
| 163 | 1997 | Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-99 | Sekar, K; Yu, BZ; Rogers, J; Lutton, J; Liu, X; Chen, X; Tsai, MD ; Jain, MK; Sundaralingam, M | Biochemistry 36, 3104-3114 | | | |
| 164 | 1997 | DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant | Ahn, J; Werneburg, BG; Tsai, MD | Biochemistry 36, 1100-1107 | | | |
| 165 | 1997 | Mechanism of phosphatidylinositol-phospholipase C .2. Reversal of a thio effect by site-directed mutagenesis | Hondal, RJ; Bruzik, KS; Zhao, Z; Tsai, MD | J Am Chem Soc 119, 5477-5478 | | | |
| 166 | 1997 | DNA polymerase beta: multiple conformational changes in the mechanism of catalysis | Zhong, X; Patel, SS; Werneburg, BG; Tsai, MD | Biochemistry 36, 11891-11900 | | | |
| 167 | 1997 | SYNTHESIS OF ENANTIOMERICALLY PURE PHOSPHOROTHIOLATE ASSAY SUBSTRATE FOR PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | Mihai, C; Mataka, J; Riddle, S; Tsai, MD ; Bruzik, KS | Bioorganic & Medicinal Chemistry Letters 7, 1235-1238 | | | |
| 168 | 1997 | Phosphatidylinositol-specific phospholipase C .3. Elucidation of the catalytic mechanism and comparison with ribonuclease A1 | Hondal, R. J.; Zhao, Z.; Riddle, S. R.; Kravchuk, A. V.; Liao, H.; Bruzik, K. S.; Tsai, M. D. | J Am Chem Soc 119, 9933-9934 | | | |
| 169 | 1997 | Natural Product Chemistry: From Plants to Human | Tsai, M. D. | Journal of the Chinese Chemical Society 44, 183-186 | | | |
| 170 | 1997 | Phosphatidylinositol-specific phospholipase C: kinetic and stereochemical evidence for an interaction between arginine-69 and the phosphate group of phosphatidylinositol | Hondal, R. J.; Riddle, S. R.; Kravchuk, A. V.; Zhao, Z.; Liao, H.; Bruzik, K. S.; Tsai, M. D. | Biochemistry 36, 6633-6642 | | | |
| 171 | 1997 | DNA polymerase beta: analysis of the contributions of tyrosine-271 and asparagine-279 to substrate specificity and fidelity of DNA replication by pre-steady-state kinetics | Kraynov, V. S.; Werneburg, B. G.; Zhong, X.; Lee, H.; Ahn, J.; Tsai, M. D. | Biochem J 323, 103-111 | | | |
| 172 | 1997 | Use of Unnatural Amino Acids to Probe the Importance of the Aromaticity in Tyrosine-95 and the Ring Size in Proline-17 in Adenylate Kinase | Zhao, Z; Liu, X; Shi, Z; Huang, B; Jiang, RT; Tsai, MD | Youji Huaxue 17, 20-23 | | | |
| 173 | 1996 | Perspectives on Protein Engineering | Huang, B.; Schaeffer, C. J.; Tsai, M. D. | | | | |
| 174 | 1996 | Mechanism of adenylate kinase .20. Probing the importance of the aromaticity in tyrosine-95 and the ring size in proline-17 with unnatural amino acids | Zhao, Z; Liu, XH; Shi, ZT; Danley, L; Huang, BH; Jiang, RT; Tsai, MD | J Am Chem Soc 118, 3535-3536 | | | |
| 175 | 1996 | Splase: The Design of a New Restriction Enzyme with Specificity for Sp1 Binding Sites | Huang, B; Schaeffer, CJ; Tsai, MD | Perspectives on Protein Engineering 3 | | | |
| 176 | 1996 | Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism | Tevelev, A; Byeon, IJ; Selby, T; Ericson, K; Kim, HJ; Kraynov, V; Tsai, MD | Biochemistry 35, 9475-9487 | | | |
| 177 | 1996 | Design, synthesis and biochemical applications of analogs of phosphatidylinositol | Bhamare, N; Wang, YP; Tsai, MD ; Bruzik, KS | Phosphorus Sulfur and Silicon and the Related Elements 10991-4), 317-320 | | | |
| 178 | 1996 | Splase: a new class IIS zinc-finger restriction endonuclease with specificity for Sp1 binding sites | Huang, B; Schaeffer, CJ; Li, Q; Tsai, MD | Journal of Protein Chemistry 15, 481-489 | | | |
| 179 | 1996 | Binding proteins on synaptic membranes for certain phospholipases A2 with presynaptic toxicity | Tzeng, M. C.; Yen, C. H.; Tsai, M. D. | Adv Exp Med Biol 391, 271-278 | | | |
| 180 | 1996 | Synthesis of inositol phosphodiesters by phospholipase C-catalyzed transesterification | Bruzik, K. S.; Guan, Z. W.; Riddle, S.; Tsai, M. D. | J Am Chem Soc 118, 7679-7688 | | | |
| 181 | 1996 | Effects of Glycosylation of a Peptide Epitope from HTLV-1 gp46 on Structure and Immunogenicity | Conrad, S. F.; Byeon, I. J. L; DiGeorge, A. M.; Lairmore, M. D.; Tsai, M. D. ; Kaumaya, P. T. P. | Chem Struct Biol, Proc Am Pept Symp 448-449 | | | |
| 182 | 1996 | DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity | Werneburg, B. G.; Ahn, J.; Zhong, X.; Hondal, R. J.; Kraynov, V. S.; Tsai, M. D. | Biochemistry 35, 7041-7050 | | | |
| 183 | 1996 | Structure-Function Relationship of Adenylate Kinase. 19. Glutamine-101 in AMP Specificity | Beichner, S; Byeon, IJ; Tsai, MD | PEPTIDES: Chemistry, Structure, and Biology 721-723 | | | |
| 184 | 1996 | Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface | Huang, B; Yu, BZ; Rogers, J; Byeon, IJ; Sekar, K; Chen, X; Sundaralingam, M; Tsai, MD ; Jain, MK | Biochemistry 35, 12164-12174 | | | |
| 185 | 1995 | Phospholipase A2 engineering. The roles of disulfide bonds in structure, conformational stability, and catalytic function | Zhu, H; Dupureur, CM; Zhang, X; Tsai, MD | Biochemistry 34, 15307-15314 | | | |
| 186 | 1995 | Mechanism of adenylate kinase. The ""essential lysine"" helps to orient the phosphates and the active site residues to proper conformations | Byeon, L; Shi, Z; Tsai, MD | Biochemistry 34, 3172-3182 | | | |
| 187 | 1995 | Conversion of bovine pancreatic phospholipase A2 at a single site into a competitor of neurotoxic phospholipases A2 by site-directed mutagenesis | Tzeng, MC; Yen, CH; Hseu, MJ; Dupureur, CM; Tsai, MD | J Biol Chem 270, 2120-2123 | | | |
| 188 | 1995 | Immunogenicity and conformational properties of an N-linked glycosylated peptide epitope of human T-lymphotropic virus type 1 (HTLV-I) | Conrad, S. F.; Byeon, I. J.; DiGeorge, A. M.; Lairmore, M. D.; Tsai, M. D. ; Kaumaya, P. T. | Biomed Pept Proteins Nucleic Acids 1, 83-92 | | | |
| 189 | 1995 | Binding proteins on synaptic membranes for crotoxin and taipoxin, two phospholipases A2 with neurotoxicity | Tzeng, M. C.; Yen, C. H.; Hseu, M. J.; Tseng, C. C.; Tsai, M. D. ; Dupureur, C. M. | Toxicon 33, 451-457 | | | |
| 190 | 1995 | Manipulating phosphorus stereospecificity of adenylate kinase by site-directed mutagenesis | Tsai, M. D. ; Jiang, R. T.; Dahnke, T.; Shi, Z. | Methods in Enzymology 249, 425-443 | | | |
| 191 | 1995 | Phospholipase A2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMR | Liu, X; Zhu, H; Huang, B; Rogers, J; Yu, BZ; Kumar, A; Jain, MK; Sundaralingam, M; Tsai, MD | Biochemistry 34, 7322-7334 | | | |
| 192 | 1994 | Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water | Kumar, A; Sekharudu, C; Ramakrishnan, B; Dupureur, CM; Zhu, H; Tsai, MD ; Sundaralingam, M | Protein Sci 3, 2082-2088 | | | |
| 193 | 1994 | A small, high-copy-number vector suitable for both in vitro and in vivo gene expression | Huang, B; Shi, Z; Tsai, MD | Gene 151, 143-145 | | | |
| 194 | 1994 | Mechanism of adenylate kinase. The conserved aspartates 140 and 141 are important for transition state stabilization instead of substrate-induced conformational changes | Dahnke, T; Tsai, MD | J Biol Chem 269, 8075-8081 | | | |
| 195 | 1994 | Phospholipase A2 engineering. Structural and functional roles of the highly conserved active site residue aspartate-49 | Li, Y; Yu, BZ; Zhu, H; Jain, MK; Tsai, MD | Biochemistry 33, 14714-14722 | | | |
| 196 | 1994 | Toward the mechanism of phosphoinositide-specific phospholipases C | Bruzik, K. S.; Tsai, M. D. | Bioorganic & Medicinal Chemistry 2, 49-72 | | | |
| 197 | 1994 | Are D- and L-chiro-phosphoinositides substrates of phosphatidylinositol-specific phospholipase C? | Bruzik, K. S.; Hakeem, A. A.; Tsai, M. D. | Biochemistry 33, 8367-8374 | | | |
| 198 | 1993 | Mechanism of adenylate kinase. What can be learned from a mutant enzyme with minor perturbation in kinetic parameters? | Shi, Z; Byeon, IJ; Jiang, RT; Tsai, MD | Biochemistry 32, 6450-6458 | | | |
| 199 | 1993 | Mechanism of adenylate kinase. 1H, 13C, and 15N NMR assignments, secondary structures, and substrate binding sites | Byeon, I. J.; Yan, H.; Edison, A. S.; Mooberry, E. S.; Abildgaard, F.; Markley, J. L.; Tsai, M. D. | Biochemistry 32, 12508-12521 | | | |
| 200 | 1993 | Phospholipase A2 engineering. 10. The aspartate...histidine catalytic diad also plays an important structural role | Li, Y. S.; Tsai, M. D. | J Am Chem Soc 115, 8523-8526 | | | |
| 201 | 1992 | Mechanism of adenylate kinase. Structural and functional roles of the conserved arginine-97 and arginine-132 | Dahnke, T; Shi, Z; Yan, H; Jiang, RT; Tsai, MD | Biochemistry 31, 6318-6328 | | | |
| 202 | 1992 | Practical Synthesis of Enantiomerically Pure myo-Inositol Derivatives | Bruzik, K. S.; Myers, J.; Tsai, M. D. | Tetrahedron Lett 33, 1009-1012 | | | |
| 203 | 1992 | Modification of a Bruker AM-600 Spectrometer for Double and Triple Resonance Three Dimensional and Four Dimensional Experiments Illustrated with Chicken Adenylate Kinase Resonance Assignments | Mooberry, E. S.; Edison, A. S.; Abildgaard, F.; Markley, J. L.; Byeon, I. J. L.; Tsai, M. D. | Proceedings of the International Symposium on Spectroscopy and Structure of Molecules and Nuclei 375-380 | | | |
| 204 | 1992 | Efficient and Systematic Syntheses of Enantiomerically Pure and Regiospecifically Protected Myoinositols | Bruzik, K. S.; Tsai, M. D. | J Am Chem Soc 114, 6361-6374 | | | |
| 205 | 1992 | Phospholipase A2 engineering. Structural and functional roles of highly conserved active site residues tyrosine-52 and tyrosine-73 | Dupureur, C. M.; Yu, B. Z.; Jain, M. K.; Noel, J. P.; Deng, T.; Li, Y.; Byeon, I. J.; Tsai, M. D. | Biochemistry 31, 6402-6413 | | | |
| 206 | 1992 | Interfacial catalysis by phospholipase A2: the rate-limiting step for enzymatic turnover | Jain, M. K.; Yu, B. Z.; Rogers, J.; Gelb, M. H.; Tsai, M. D. ; Hendrickson, E. K.; Hendrickson, H. S. | Biochemistry 31, 7841-7847 | | | |
| 207 | 1992 | Phospholipase A2 engineering. 6. Single amino acid substitutions of active site residues convert the rigid enzyme to highly flexible conformational states | Dupureur, C. M.; Li, Y. S.; Tsai, M. D. | J Am Chem Soc 114, 2748-2749 | | | |
| 208 | 1992 | Phospholipase A2 engineering. The structural and functional roles of aromaticity and hydrophobicity in the conserved phenylalanine-22 and phenylalanine-106 aromatic sandwich | Dupureur, C. M.; Yu, B. Z.; Mamone, J. A.; Jain, M. K.; Tsai, M. D. | Biochemistry 31, 10576-10583 | | | |
| 209 | 1992 | Phospholipids chiral at phosphorus. Stereochemical mechanism for the formation of inositol 1-phosphate catalyzed by phosphatidylinositol-specific phospholipase C | Bruzik, K. S.; Morocho, A. M.; Jhon, D. Y.; Rhee, S. G.; Tsai, M. D. | Biochemistry 31, 5183-5193 | | | |
| 210 | 1992 | Crystal structure of the Y52F/Y73F double mutant of phospholipase A2: increased hydrophobic interactions of the phenyl groups compensate for the disrupted hydrogen bonds of the tyrosines | Sekharudu, C; Ramakrishnan, B; Huang, B; Jiang, RT; Dupureur, CM; Tsai, MD ; Sundaralingam, M | Protein Sci 1, 1585-1594 | | | |
| 211 | 1991 | Mechanism of Adenylate Kinase .12. Prediction and Demonstration of Enhancement of Phosphorus Stereospecificity by Site-Directed Mutagenesis | Dahnke, T; Jiang, RT; Tsai, MD | J Am Chem Soc 113, 9388-9389 | | | |
| 212 | 1991 | Mechanism of adenylate kinase. Demonstration of a functional relationship between aspartate 93 and Mg2+ by site-directed mutagenesis and proton, phosphorus-31, and magnesium-25 NMR | Yan, H. G.; Tsai, M. D. | Biochemistry 30, 5539-5546 | | | |
| 213 | 1991 | Phosphorothioate Analogs of Phosphatidylinositol and Inositol 1,2-Cyclic Phosphate - Application to the Mechanism of Phospholipase-C | Bruzik, K. S.; Lin, G. L.; Tsai, M. D. | ACS Symposium Series 463, 172-185 | | | |
| 214 | 1991 | Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates | Noel, J. P.; Bingman, C. A.; Deng, T. L.; Dupureur, C. M.; Hamilton, K. J.; Jiang, R. T.; Kwak, J. G.; Sekharudu, C.; Sundaralingam, M.; Tsai, M. D. | Biochemistry 30, 11801-11811 | | | |
| 215 | 1991 | Mechanism of adenylate kinase: site-directed mutagenesis versus X-ray and NMR | Tsai, M. D. ; Yan, H. G. | Biochemistry 30, 6806-6818 | | | |
| 216 | 1991 | Phospholipase stereospecificity at phosphorus | Bruzik, K. S.; Tsai, M. D. | Methods in Enzymology 197, 258-269 | | | |
| 217 | 1991 | Mechanism of Adenylate Kinase .10. Reversing Phosphorus Stereospecificity by Site-Directed Mutagenesis | Jiang, R. T.; Dahnke, T.; Tsai, M. D. | J Am Chem Soc 113, 5485-5486 | | | |
| 218 | 1990 | Phospholipase A2 engineering. 4. Can the active-site aspartate-99 function alone? | Dupureur, C. M.; Deng, T. L.; Kwak, J. G.; Noel, J. P.; Tsai, M. D. | J Am Chem Soc 112, 7074-7076 | | | |
| 219 | 1990 | Phospholipids Chiral at Phosphorus .19. Synthesis and Configurational Assignment of Phosphorothioate Analogs of Phosphatidylserine | Loffredo, W. M.; Tsai, M. D. | Bioorg Chem 18, 78-84 | | | |
| 220 | 1990 | Phospholipids chiral at phosphorus. Stereochemical mechanism of reactions catalyzed by phosphatidylinositide-specific phospholipase C from Bacillus cereus and guinea pig uterus | Lin, G. L.; Bennett, C. F.; Tsai, M. D. | Biochemistry 29, 2747-2757 | | | |
| 221 | 1990 | Phospholipase A2 engineering. 3. Replacement of lysine-56 by neutral residues improves catalytic efficiency significantly, alters substrate specificity, and clarifies the mechanism of interfacial recognition | Noel, J. P.; Deng, T.; Hamilton, K. J.; Tsai, M. D. | J Am Chem Soc 112, 3704-3706 | | | |
| 222 | 1990 | Mechanism of adenylate kinase. Structural and functional demonstration of arginine-138 as a key catalytic residue that cannot be replaced by lysine | Yan, H. G.; Shi, Z. T.; Tsai, M. D. | Biochemistry 29, 6385-6392 | | | |
| 223 | 1990 | Mechanism of adenylate kinase. Critical evaluation of the X-ray model and assignment of the AMP site | Yan, H. G.; Dahnke, T.; Zhou, B. B.; Nakazawa, A.; Tsai, M. D. | Biochemistry 29, 10956-10964 | | | |
| 224 | 1990 | Mechanism of adenylate kinase. Are the essential lysines essential? | Tian, G. C.; Yan, H. G.; Jiang, R. T.; Kishi, F.; Nakazawa, A.; Tsai, M. D. | Biochemistry 29, 4296-4304 | | | |
| 225 | 1990 | A novel expression vector for high-level synthesis and secretion of foreign proteins in Escherichia coli: overproduction of bovine pancreatic phospholipase A2 | Deng, TL; Noel, JP; Tsai, MD | Gene 93, 229-234 | | | |
| 226 | 1990 | Phospholipids Chiral at Phosphorus. 22. Phospholipids Chiral at Phosphorus - Synthesis of Dioleoylthiophosphatidylcholine and Stereospecificity of Lecithin-Cholesterol Acyltransferase | Rosariojansen, T; Pownal, H; Jiang, RT; Tsai, MD | Bioorg Chem 18, 179-184 | | | |
| 227 | 1989 | Mechanism of adenylate kinase. Is there a relationship between local substrate dynamics, local binding energy, and the catalytic mechanism? | C. R. Sanders; Tian, G. C.; Tsai, M. D. | Biochemistry 28, 9028-9043 | | | |
| 228 | 1989 | Ligand-protein interactions via nuclear magnetic resonance of quadrupolar nuclei | C. R. Sanders; Tsai, M. D. | Methods in Enzymology 177, 317-333 | | | |
| 229 | 1989 | Phospholipids chiral at phosphorus. 18. Stereochemistry of phosphatidylinositide-specific phospholipase C | Lin, G; Tsai, MD | J Am Chem Soc 111, 3099-3101 | | | |
| 230 | 1989 | Phospholipase A2 engineering: design, synthesis, and expression of a gene for bovine (pro)phospholipase A2 | Noel, JP; Tsai, MD | J Cell Biochem 40, 309-320 | | | |
| 231 | 1988 | Steric Course of the Reaction Catalyzed by Phosphatidylserine Decarboxylase from Escherichia-Coli | No, Z. S.; Sanders, C. R.; Dowhan, W.; Tsai, M. D. | Bioorg Chem 16, 184-188 | | | |
| 232 | 1988 | Phospholipids chiral at phosphorus. Characterization of the sub-gel phase of thiophosphatidylcholines by use of X-ray diffraction, phosphorus-31 nuclear magnetic resonance, and Fourier transform infrared spectroscopy | Sarvis, H. E.; Loffredo, W.; Dluhy, R. A.; Hernqvist, L.; Wisner, D. A.; Tsai, M. D. | Biochemistry 27, 4625-4631 | | | |
| 233 | 1988 | Phospholipids chiral at phosphorus. Synthesis and stereospecificity of phosphorothioate analogues of platelet-activating factor | Jansen, T. Rosario; Jiang, R. T.; Tsai, M. D. ; Hanahan, D. J. | Biochemistry 27, 4619-4624 | | | |
| 234 | 1988 | Mechanism of Adenylate Kinase .3. Use of Deuterium Nmr to Show Lack of Correlation between Local Substrate Dynamics and Local Binding-Energy | C. R. Sanders; Tsai, M. D. | J Am Chem Soc 110, 3323-3324 | | | |
| 235 | 1988 | Mechanism of adenylate kinase. Histidine-36 is not directly involved in catalysis, but protects cysteine-25 and stabilizes the tertiary structure | Tian, GC; Sanders, CR 2nd; Kishi, F; Nakazawa, A; Tsai, MD | Biochemistry 27, 5544-5552 | | | |
| 236 | 1988 | Use of short-chain cyclopentano-phosphatidylcholines to probe the mode of activation of phospholipase A2 from bovine pancreas and bee venom | Lin, G; Noel, J; Loffredo, W; Stable, HZ; Tsai, MD | J Biol Chem 263, 13208-13214 | | | |
| 237 | 1987 | Biophosphates and Their Analogues, Synthesis, Structure, Metabolism and Activity | Tsai, M. D. ; Bruzik, K. S.; Wisner, D.; Liu, S. H. | | | | |
| 238 | 1987 | Phospholipids chiral at phosphorus. Steric course of the reactions catalyzed by phosphatidylserine synthase from Escherichia coli and yeast | Raetz, C. R.; Carman, G. M.; Dowhan, W.; Jiang, R. T.; Waszkuc, W.; Loffredo, W.; Tsai, M. D. | Biochemistry 26, 4022-4027 | | | |
| 239 | 1987 | Phospholipids Chiral at Phosphorus .13. Stereochemical Comparison of Phospholipase-A2, Lecithin-Cholesterol Acyl Transferase, and Platelet-Activating-Factor | Rosariojansen, T.; Pownall, H. J.; Noel, J. P.; Tsai, M. D. | Phosphorus Sulfur and Silicon and the Related Elements 30, 601-604 | | | |
| 240 | 1987 | Phospholipids Chiral at Phosphorus. 14. Stereochemical Effects on the Thermotropic Properties of Thiophosphatidylcholines and Thiosphingomyelins | Tsai, M. D. ; Bruzik, K. S.; Wisner, D.; Liu, S. H. | In: Biophosphates and Their Analogues, Synthesis, Structure, Metabolism and Activity 561-570 | | | |
| 241 | 1987 | Is the binding of magnesium (II) to calmodulin significant? An investigation by magnesium-25 nuclear magnetic resonance | Tsai, M. D. ; Drakenberg, T.; Thulin, E.; Forsen, S. | Biochemistry 26, 3635-3643 | | | |
| 242 | 1987 | A calorimetric study of the thermotropic behavior of pure sphingomyelin diastereomers | Bruzik, K. S.; Tsai, M. D. | Biochemistry 26, 5364-5368 | | | |
| 243 | 1987 | Magnesium Binding to Calcium-Binding Proteins: A Regulatory Function? | Drakenberg, T; Forsen, S; Thulin, E; Tsai, MD | In: Calcium-Binding Proteins in Health and Disease 430-432 | | | |
| 244 | 1986 | Mechanisms of Enzymatic Reactions: Stereochemistry | Tsai, M. D. ; Bruzik, K.; Hart, J.; Jiang, R. T.; Jansen, T. Rosario; Tsai, T. C.; Wisner, D. A. | | | | |
| 245 | 1986 | Phospholipids chiral at phosphorus: Fourier-transform infrared study on the gel-liquid crystalline transition of chiral thiophosphatidylcholine | Chang, S. B.; Alben, J. O.; Wisner, D. A.; Tsai, M. D. | Biochemistry 25, 3435-3440 | | | |
| 246 | 1986 | Phospholipids Chiral at Phosphorus. 10. Use of Chiral Thiophospholipids to Study the Mechanism of Phospholipase A2 | Tsai, M. D. ; Bruzik, K.; Hart, J.; Jiang, R. T.; Jansen, T. Rosario; Tsai, T. C.; Wisner, D. A. | In: Mechanisms of Enzymatic Reactions: Stereochemistry 115-126 | | | |
| 247 | 1986 | Phospholipids Chiral at Phosphorus .12. Configurational Effect on the Thermotropic Properties of Chiral Dipalmitoylthiophosphatidylcholine | Wisner, D. A.; Rosariojansen, T.; Tsai, M. D. | J Am Chem Soc 108, 8064-8068 | | | |
| 248 | 1985 | Metal-nucleotide interactions. 3. Oxygen-17, phosphorus-31, and proton NMR studies on the interaction of scandium(III), lanthanum(III), and lutetium(III) with adenosine 5'-triphosphate | Shyy, YJ; Tsai, TC; Tsai, MD | Journal of the American Chemical Society 107(12), 3478-3484 | | | |
| 249 | 1985 | Phospholipids chiral at phosphorus. Use of chiral thiophosphatidylcholine to study the metal-binding properties of bee venom phospholipase A2 | Tsai, T. C.; Hart, J.; Jiang, R. T.; Bruzik, K.; Tsai, M. D. | Biochemistry 24, 3180-3188 | | | |
| 250 | 1985 | Mechanism of adenylate kinase. 1. Use of oxygen-17 NMR to study the binding properties of substrates | Wisner, D. A.; Steginsky, C. A.; Shyy, Y. J.; Tsai, M. D. | J Am Chem Soc 107, 2814-2815 | | | |
| 251 | 1984 | 31P NMR: Principles and Applications | Tsai, M. D. | | | | |
| 252 | 1984 | Use of Chiral thiophosphates and the Stereochemistry of Enzymatic Phosphoryl Transfer | Tsai, M. D. | In: 31P NMR: Principles and Applications 175-197 | | | |
| 253 | 1984 | Phospholipids chiral at phosphorus. Properties of small unilamellar vesicles of chiral thiophosphatidylcholine | Tsai, T. C.; Jiang, R. T.; Tsai, M. D. | Biochemistry 23, 5564-5570 | | | |
| 254 | 1984 | Stereochemistry of Biological Reactions at Proprochiral Centers | Floss, H. G.; Tsai, M. D. ; Woodard, R. W. | Topics in Stereochemistry 15, 253-321 | | | |
| 255 | 1984 | Phospholipids chiral at phosphorus. Absolute configuration of chiral thiophospholipids and stereospecificity of phospholipase D | Jiang, R. T.; Shyy, Y. J.; Tsai, M. D. | Biochemistry 23, 1661-1667 | | | |
| 256 | 1984 | Phospholipids chiral at phosphorus. Synthesis of chiral phosphatidylcholine and stereochemistry of phospholipase D | Bruzik, K; Tsai, MD | Biochemistry 23, 1656-1661 | | | |
| 257 | 1984 | Phospholipids chiral at phosphorus. 5. Synthesis and configurational analysis of chiral [17O,18O]phosphatidylethanolamine | Bruzik, K; Tsai, MD | J Am Chem Soc 106, 747-754 | | | |
| 258 | 1983 | Phospholipids Chiral at Phosphorus - Synthesis, Absolute-Configurations and Applications | Bruzik, K. S.; Jiang, R. T.; Tsai, M. D. | Phosphorus Sulfur and Silicon and the Related Elements 18, 369-372 | | | |
| 259 | 1983 | NMR Methods Involving Oxygen Isotopes in Biophosphates | Tsai, M. D. ; Bruzik, K. | Biological Magnetic Resonance 5, 129-181 | | | |
| 260 | 1983 | Phospholipids Chiral at Phosphorus .4. Could Membranes Be Chiral at Phosphorus? | Tsai, M. D. ; Jiang, R. T.; Bruzik, K. | J Am Chem Soc 105, 2478-2480 | | | |
| 261 | 1983 | Effects of oxygen-17 and oxygen-18 on phosphorus-31 NMR: further investigation and applications | Sammons, R. D.; Frey, P. A.; Bruzik, K.; Tsai, M. D. | J Am Chem Soc 105, 5455-5461 | | | |
| 262 | 1983 | Phospholipids chiral at phosphorus. Preparation and spectral properties of chiral thiophospholipids | Bruzik, K; Jiang, RT; Tsai, MD | Biochemistry 22, 2478-2486 | | | |
| 263 | 1982 | Phospholipids Chiral at Phosphorus .2. Preparation, Property, and Application of Chiral Thiophospholipids | Bruzik, K; Gupte, SM; Tsai, MD | J Am Chem Soc 104, 4682-4684 | | | |
| 264 | 1982 | Phospholipids chiral at phosphorus. 1. Stereochemistry of transphosphatidylation catalyzed by phospholipase D | Bruzik, K; Tsai, MD | J Am Chem Soc 104, 863-865 | | | |
| 265 | 1982 | Does the magnesium(II) ion interact with the alpha-phosphate of adenosine triphosphate? An investigation by oxygen-17 nuclear magnetic resonance | Huang, S. L.; Tsai, M. D. | Biochemistry 21, 951-959 | | | |
| 266 | 1982 | Use of 31P(18O), 31P(17O), and 17O NMR methods to study enzyme mechanisms involving phosphorus | Tsai, M. D. | Methods in Enzymology 87, 235-279 | | | |
| 267 | 1981 | Protein crystals, membrane proteins and membrane lipids. Recent advances in the study of their static and dynamic structures using nuclear magnetic resonance spectroscopic techniques | Oldfield, E; Janes, N; Kinsey, R; Kintanar, A; Lee, RW; Rothgeb, TM; Schramm, S; Skarjune, R; Smith, R; Tsai, MD | Biochemical Society Symposium (46), 155-181 | | | |
| 268 | 1981 | First observation of amino acid side chain dynamics in membrane proteins using high field deuterium nuclear magnetic resonance spectroscopy | Kinsey, R. A.; Kintanar, A.; Tsai, M. D. ; Smith, R. L.; Janes, N.; Oldfield, E. | J Biol Chem 256, 4146-4149 | | | |
| 269 | 1980 | Stereochemistry of the hydrolysis of adenosine 5'-thiophosphate catalyzed by venom 5'-nucleotidase | Tsai, MD | Biochemistry 19, 5310-5316 | | | |
| 270 | 1980 | Chirality at a pro-pro-prochiral phosphorus center. Stereochemical course of the 5'-nucleotidase-catalyzed reaction | Tsai, MD ; Chang, TT | J Am Chem Soc 102, 5416-5418 | | | |
| 271 | 1980 | Applicability of the phosphorus-31 (oxygen-17) nuclear magnetic resonance method in the study of enzyme mechanism involving phosphorus | Tsai, M. D. ; Huang, S. L.; Kozlowski, J. F.; Chang, C. C. | Biochemistry 19, 3531-3536 | | | |
| 272 | 1980 | Stereochemical course of the transmethylation catalyzed by catechol O-methyltransferase | Woodard, R. W.; Tsai, M. D. ; Floss, H. G.; Crooks, P. A.; Coward, J. K. | J Biol Chem 255, 9124-9127 | | | |
| 273 | 1979 | Chiral methyl groups | Floss, HG; Tsai, MD | Adv Enzymol Relat Areas Mol Biol 50, 243-302 | | | |
| 274 | 1979 | Transmethylation | Floss, H. G.; Mascaro, L.; Tsai, M. D. ; Woodard, R. W. | | | | |
| 275 | 1979 | Use of phosphorus-31 nuclear magnetic resonance to distinguish bridge and nonbridge oxygens of oxygen-17-enriched nucleoside triphosphates. Stereochemistry of acetate activation by acetyl coenzyme A synthetase | Tsai, M. D. | Biochemistry 18, 1468-1472 | | | |
| 276 | 1979 | Stereochemistry and mechanism of reactions catalyzed by indolyl-3-alkane alpha-hydroxylase | Tsai, M. D. ; Floss, H. G.; Rosenfeld, H. J.; Roberts, J. | J Biol Chem 254, 6437-6443 | | | |
| 277 | 1979 | Stereochemistry of Enzymatic Transmethylation | Floss, H. G.; Mascaro, L.; Tsai, M. D. ; Woodard, R. W. | In: Transmethylation 135-141 | | | |
| 278 | 1978 | Conformational analysis of pyridoxal Schiff's bases. Nuclear magnetic resonance studies of the conformations about the C4-C4', Calpha-Cbeta, and N-Calpha bonds of the pyridoxal Schiff's bases of amino acids | Tsai, M. D. ; Byrn, S. R.; Chang, C.; Floss, H. G.; Weintraub, H. J. | Biochemistry 17, 3177-3182 | | | |
| 279 | 1978 | Stereochemistry of the beta-cyanoalanine synthetase and S-alkylcysteine lyase reactions | Tsai, M. D. ; Weaver, J.; Floss, H. G.; Conn, E. E.; Creveling, R. K.; Mazelis, M. | Arch. Biochem. Biophys. 190, 553-559 | | | |
| 280 | 1978 | Conformation-reactivity relationship for pyridoxal Schiff's bases. Rates of racemization and alpha-hydrogen exchange of the pyridoxal Schiff's bases of amino acids | Tsai, M. D. ; Weintraub, H. J.; Byrn, S. R.; Chang, C.; Floss, H. G. | Biochemistry 17, 3183-3188 | | | |
| 281 | 1978 | Stereochemistry and mechanism of reactions catalyzed by tryptophanase Escherichia coli | Vederas, J. C.; Schleicher, E.; Tsai, M. D. ; Floss, H. G. | J Biol Chem 253, 5350-5354 | | | |
| 282 | 1978 | Stereochemistry and mechanism of reactions catalyzed by tryptophan synthetase and its beta2 subunit | Tsai, M. D. ; Schleicher, E.; Potts, R.; Skye, G. E.; Floss, H. G. | J Biol Chem 253, 5344-5349 | | | |
| 283 | 1976 | Conformational Analysis of Pyridoxal Amino Acid Schiffs Bases | Weintraub, H. J. R.; Tsai, M. D. ; Byrn, S. R.; Chang, C. J.; Floss, H. G. | International Journal of Quantum Chemistry 10(S3), 99-105 | | | |
| 284 | 1975 | Dye-sensitized Photooxidation of a-Terpineol | Cheng, Y. S.; Tsai, M. D. ; Fang, J. M.; Hsu, S. S. | Chemistry (The Chinese Chem. Soc., Taiwan, China) 1, 8-11 | | | |
| 285 | 1974 | Air Oxidation of a-Terpineol | Tsai, M. D. ; Cheng, Y. S. | Journal of the Chinese Chemical Society 21, 149-155 | | | |
| 286 | 1972 | Terpenes and Sterols of Cunninghamia Konishii | Cheng, Y. S.; Tsai, M. D. | Phytochemistry 11, 2108-2109 | | | |
| 287 | - | How a half-sized DNA polymerase catalyzes non-Watson-Crick dG:dGTP incorporation | Wen-Jin Wu; Mei-I Su; Sandeep Kumar; Ming-Chuan Chad Chen; Chun-Wei Eric Wang; Ming-Daw Tsai | | | | |
