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Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
12022Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use.Tu, IF; Lin, TL; Yang, FL; Lee, IM; Tu, WL; Liao, JH; Ko, TP; Wu, WJ ; Jan, JT ; Ho, MR ; Chou, CY; Wang, AH ; Wu, CY ; Wang, JT; Huang, KF ; Wu, SH Journal of Biomedical Science 29, 9
22017The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNABo-Lin Lin; Chin-Yu Chen; Chun-Hsiang Huang; Tzu-Ping Ko; Cheng-Hung Chiang; Kuan-Fu Lin; Yuan-Chih Chang ; Po-Yen Lin ; Hui-Hsu Gavin Tsai; Andrew H.-J. Wang PLOS ONE 12(1), e0169627
32016Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.Zhang, L; Chen, CC; Ko, TP; Huang, JW; Zheng, Y; Liu, W; Wang, I; Malwal, SR; Feng, X; Wang, K; Huang, CH; Hsu, STD ; Wang, AH ; Oldfield, E; Guo, RTANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55(15), 4716-20
42016Exploring the Mechanism Responsible for Cellulase Thermostability by Structure-Guided RecombinationChia-Jung Chang; Cheng-Chung Lee; Yueh-Te Chan; Devin L. Trudeau; Mei- Huey Wu; Chih-Hsuan Tsai; Su-May Yu ; Tuan-Hua David Ho ; Andrew H.-J. Wang ; Chwan-Deng Hsiao ; Frances H. Arnold; Yu-Chan Chao PLoS ONE 11 (3):e0147485
52015Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms.Han, X; Chen, CC; Kuo, CJ; Huang, CH; Zheng, Y; Ko, TP; Zhu, Z; Feng, X; Wang, K; Oldfield, E; Wang, AH ; Liang, PH ; Guo, RT; Ma, YProteins 83(1), 37-45
62015Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.Chen, KE; Li, MY; Chou, CC; Ho, MR ; Chen, GC ; Meng, TC ; Wang, AH Structure (London, England : 1993) 23(4), 653-64
72014Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain–modulated complex formationChen, KE; Lin, SY; Wu, MJ; Ho, MR ; Santhanam, A; Chou, CC; Meng, TC ; Wang, AH Science signaling 7(347), ra98
82013Crystal Structure of Vaccinia Viral A27 Protein Reveals a Novel Structure Critical for Its Function and Complex Formation with A26 ProteinT.-H. Chang; S.-J. Chang; F.-L. Hsieh; T.-P. Ko; C.-T. Lin; M.-R. Ho ; I. Wang; S.-T. D. Hsu ; R.-T. Guo; W. Chang ; A. H.-J. Wang PLoS Pathogens 9(8), e1003563
92012Mutations in the substrate entrance region of β-glucosidase from Trichoderma reesei improve enzyme activity and thermostabilityLee, HL; Chang, CK; Jeng, WY; Wang, AH ; Liang, PH Protein engineering design & selection 25(11), 733-740
102011Structural and functional analysis of three β-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensisJeng, WY; Wang, NC; Lin, MH; Lin, CT; Liaw, YC ; Chang, WJ; Liu, CI; Liang, PH ; Wang, AHJ Journal of structural biology 173(1), 46-56
112011Modulation of Substrate Specificities of D-Sialic Acid Aldolase through Single Mutations of Val-251.Chou, CY; Ko, TP; Wu, KJ; Huang, KF ; Lin, CH ; Wong, CH ; Wang, AH JOURNAL OF BIOLOGICAL CHEMISTRY 286(16), 14057-14064
122010The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activitiesChung, KM; Cheng, JH; Suen, CS; Huang, CH; Tsai, CH; Huang, LH; Chen, YR; Wang, AHJ ; Jiaang, WT; Hwang, MJ ; Chen, XPROTEIN SCIENCE 19(9), 1627-1638
132010Analysis of functional domains of ParB that involves in chromosome partition in Streptomyces coelicolorPao, Yiwen; Huang, Kai-Fa ; Lin, Yuan-Chi; Wang, Andrew HJ ; Shih, Yu-Ling 
142010Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation.Chang, TH; Hsieh, FL; Ko, TP; Teng, KH; Liang, PH ; Wang, AHJ The Plant Cell 22(2), 454-467
152010Structural Basis of α-Fucosidase Inhibition by Iminocyclitols with Ki Values in the Micro- to Picomolar RangeWu, HJ; Ho, CW; Ko, TP; Popat, SD; Lin, CH ; Wang, AH ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 49(2), 337-340
162010Analysis of functional domains of ParB that involves in chromosome partition in Streptomyces coelicolorPao, Yiwen; Huang, Kai-Fa ; Lin, Yuan-Chi; Wang, Andrew HJ ; Shih, Yu-Ling 
172009Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity.Chang, Yu-Wei; Ko, Tzu-Ping; Lee, Chien-Der; Chang, Yuan-Chih; Lin, Kuai-Ann; Chang, Chia-Seng ; Wang, Andrew H. -J. ; Wang, Ting-Fang PLoS ONE 4(3), e4890
182008Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.Chen, C K-M; Hudock, MP; Zhang, Y; Guo, RT; Cao, R; No, JH; Liang, PH ; Ko, TP; Chang, TH; Chang, SC; Song, Y; Axelson, J; Kumar, A; Wang, AHJ ; Oldfield, EJournal of medicinal chemistry 51(18), 5594-5607
192008Crystal structure of DFA0005 complexed with alpha-ketoglutarate: a novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus.Liao, CJ; Chin, KH; Lin, CH; Tsai, PS; Lyu, PC; Young, CC; Wang, AHJ ; Chou, SHProteins 73(2), 362-371
202008Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthasesKuo, CJ; Guo, RT; Lu, IL; Liu, HG; Wu, SY; Ko, TP; Wang, AHJ ; Liang, PH Journal of biomedicine & biotechnolog 2008, 841312
212008Cysteine S-nitrosylation protects protein-tyrosine phosphatase 1B against oxidation-induced permanent inactivation.Chen, YY; Chu, HM; Pan, KT; Teng, CH; Wang, DL ; Wang, AH ; Khoo, KH ; Meng, TC The Journal of biological chemistry 283(50), 35265-35272
222007Right or left turn? RecA family protein filaments promote homologous recombination through clockwise axial rotationWang, T-F ; Chen, L-T; Wang, A H. -J. BioEssays 30(1), 48-56
232007Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RadA proteinChen, L-T; Ko, T-P; Chang, Y-W; Lin, K-A; Wang, A H. -J. ; Wang, T-F PLoS One 2(9), e858
242007Crystal structure of the left-handed archaeal RadA helical filament: Identification of a new functional motif for controlling quaternary structures and enzymatic activity of RecA family proteinsChen, L-T; Ko, T-P; Chang, Y-C; Lin, K-A; Chang, C-S; Wang, A H. -J. ; Wang, T-F Nucleic Acids Research 35(6), 1781-1801
252007Structure-Based Design and Synthesis of Highly Potent SARS-CoV 3CL Protease InhibitorsShao, Y. M.; Yang, W. B. ; Peng, H. P.; Hsu, M. F.; Tsai, K. C.; Kuo, T. H.; Wang, A. H. J. ; Liang, P. H. ; Lin, C. H. ; Yang, A. S. ; Wong, C. H. ChemBioChem 8(14), 1654-1657
262007Expression Tags for Protein ProductionHu, Su-Ming; Wang, Andrew H. -J. ; Wang, Ting-Fang ENCYCLOPEDIA OF LIFE SCIENCES (John Wiley & Sons)
272007Structure and Mechanism of Helicobacter pylori Fucosyltransferase: A BASIS FOR LIPOPOLYSACCHARIDE VARIATION AND INHIBITOR DESIGNSun, HY; Lin, SW ; Ko, TP; Pan, JF; Liu, CL; Lin, CN; Wang, AHJ ; Lin, CH Journal of Biological Chemistry 282(13), 9973-9982
282007Bisphosphonates target multiple sites in both cis- and trans-prenyltransferasesGuo, RT; Cao, R; Liang, PH ; Ko, TP; Chang, TH; Hudock, MP; Jeng, WY; Chen, CK; Zhang, Y; Song, Y; Kuo, CJ; Yin, F; Oldfield, E; Wang, AHJ PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(24), 10022-10027
292007Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.Lee, CC; Kuo, CJ; Hsu, MF; Liang, PH ; Fang, JM; Shie, JJ; Wang, AHJ FEBS letters 581(28), 5454-5458
302006Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determinationChang, TH; Guo, RT; Ko, TP; Wang, AHJ ; Liang, PH The Journal of biological chemistry 281(21), 14991-15000
312006Cloning, crystallization and preliminary X-ray studies of XC2981 from Xanthomonas campestris, a putative CutA1 protein involved in copper-ion homeostasis.Lin, CH; Chin, KH; Gao, FP; Lyu, PC; Shr, HL; Wang, AHJ ; Chou, SHActa Crystallographica Section F-Structural Biology and Crystallization Communications 62(Pt 11), 1113-1115
322005Mechanism of the maturation process of SARS-CoV 3CL proteaseHsu, MF; Kuo, CJ; Chang, KT; Chang, HC; Chou, CC; Ko, TP; Shr, HL; Chang, GG; Wang, AHJ ; Liang, PH Journal of Biological Chemistry 280(35), 31257-31266
332005Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysisGuo, RT; Ko, TP; Chen, AP; Kuo, CJ; Wang, AHJ ; Liang, PH Journal of Biological Chemistry 280(21), 20762-20774
342005A novel substrate binding mode revealed by the site-directed mutagenesis studies of E. coli octaprenyl pyrophosphate synthaseKuo, CJ; Guo, RT; Li, SC; Chang, KM; Wang, AHJ ; Liang, PH Biochemistry submitted
352005Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures.Sun, HY; Ko, TP; Kuo, CJ; Guo, RT; Chou, CC; Liang, PH ; Wang, AHJ Journal of Bacteriology 187(23), 8137-8148
362005Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase.Chen, AP; Chang, SY; Lin, YC; Sun, YS; Chen, CT; Wang, AHJ ; Liang, PH The Biochemical journal 386(Pt 1), 169-176
372004Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilationChen, Y. K.; Leng, C. H.; Olivares, H.; Lee, M. H.; Chang, Y. C. ; Kung, W. M.; Ti, S. C.; Lo, Y. H.; Wang, A. H. ; Chang, C. S. ; Bishop, D. K.; Hsueh, Y. P. ; Wang, T. F. Proceedings of the National Academy of Sciences of the United States of America 101(29), 10572-10577
382004Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studiesChang, SY; Ko, TP; Chen, AP; Wang, AHJ ; Liang, PH Protein Science 13(4), 971-978
392004Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determinationGuo, RT; Kuo, CJ; Chou, CC; Ko, TP; Shr, HL; Liang, PH ; Wang, AHJ The Journal of biological chemistry 279(6), 4903-4912
402004A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl productsGuo, RT; Kuo, CJ; Ko, TP; Chou, CC; Liang, PH ; Wang, AHJ Biochemistry 43(24), 7678-7686
412004In vitro modification of human centromere protein CENP-C fragments by small ubiquitin-like modifier (SUMO) protein: definitive identification of the modification sites by tandem mass spectrometry analysis of the isopeptides.Chung, TL; Hsiao, HH; Yeh, YY; Shia, HL; Chen, YL; Liang, PH ; Wang, AH ; Khoo, KH ; Shoei-Lung, Li SThe Journal of biological chemistry 279(38), 39653-39662
422003Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthaseChang, SY; Chen, YK; Wang, AHJ ; Liang, PH Biochemistry 42(49), 14452-14459
432003Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli.Guo, RT; Ko, TP; Chou, CC; Shr, HL; Chu, HM; Tsai, YH; Liang, PH ; Wang, AHJ ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY D59, 2265-2268
442003Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and tritonChang, SY; Ko, TP; Liang, PH ; Wang, AHJ The Journal of biological chemistry 278(31), 29298-29307
452002Probing the Conformational Change of Escherichia coliUndecaprenyl Pyrophosphate Synthase during Catalysis Using an Inhibitor and Tryptophan MutantsChen, YH; Chen, AP; Chen, CT; Wang, AHJ ; Liang, PH The Journal of biological chemistry 277(9), 7369-76
462002Structure, mechanism and function of prenyltransferases.Liang, PH ; Ko, TP; Wang, AHJ EUROPEAN JOURNAL OF BIOCHEMISTRY 269(14), 3339-3354
472001Mechanism of Product Chain Length Determination and the Role of a Flexible Loop in Escherichia coliUndecaprenyl-pyrophosphate Synthase CatalysisKo, TP; Chen, YK; Robinson, H; Tsai, PC; Gao, YG; Chen, AP; Wang, AHJ ; Liang, PH The Journal of biological chemistry 276(50), 47474-47482
481997NMR Studies of the Anticancer Drug Pepleomycin and Its Complexes with DNA.Caceres-Cortes, J.; Sugiyama, H.; Ikudome, K.; Saito, I.; Wang, A. H. J. Tenth Conversation in the Discipline Biomolecular Stereodynamics, 207-225