第 1 到 44 筆結果,共 44 筆。
公開日期 | 題名 | 作者 | 關聯 | scopus | WOS | 全文 | |
---|---|---|---|---|---|---|---|
1 | 2018 | 01.故院長講座. 吳大猷院長講座「基因科技與抗老化研究」 | 沈哲鯤 | ||||
2 | 2012 | The Mammalian de novo DNA Methyltransferases DNMT3A and DNMT3B Are Also DNA 5-Hydroxymethyl Cytosine Dehydroxymethylases | Chen, C. -C.; Wang, K. -Y.; Shen, C. -K. J. | J. Biol. Chem. 287, 33116-33121 | |||
3 | 2012 | TDP-43 Regulates The Mammalian Spinogenesis Through Translational Repression of Rac1 | Majumder, P.; Tsai, K. -J.; Wu, C. -C.; Chen, Y. -T.; Bose, J. K.; Cheng, W. -C.; Fang, Y. -H.; Chen, Y. -L.; Lien, C. -C.; Cheng, S. -J.; Shen, C. -K. J. | Acta Neuropathologica 124, 231-245 | |||
4 | 2012 | The self-interaction of native TDP-43 C-terminus Inhibits; Its degradation and contributes to early proteinopathies | Wang, I. -F.; Chang, H. -Y.; Hou, S. -C.; Liou, G. -G.; Way, T. -D.; Shen, C. -K. J. | Nature Commun. 3, 766 | |||
5 | 2012 | Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43 | Wang, I. -F.; Guo, B. -S.; Liu, Y. -C.; Wu, C. -C.; Yang, C. -C.; Tsai, K. -J.; Shen, C. -K. J. | Proc Natl Acad Sci USA 109, 15024-15029 | |||
6 | 2012 | Targeted Depletion of TDP-43 Expression in the Spinal Cord Motor Neurons Leads to the Development of ALS-like Phenotypes in Mice | Wu, L. -S.; Cheng, W. -C.; Shen, C. -K. J. | J. Biol. Chem. 287, 27335-27344 | |||
7 | 2011 | Neuronal Function and Dysfunction of Drosophila dTDP | Lin, M. -J.; Cheng, C. -W.; Shen, C. -K. J. | PLoS ONE 6(6), e20371 | |||
8 | 2011 | Regulation of autophagy by the neuropathological protein TDP-43 | Bose, J. K.; Huang, C. -C.; Shen, C. -K. J. | Journal of Biological Chemistry 286, 44441-44448 | |||
9 | 2010 | Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U | Tsai, Kuen-Jer; Yang, Chun-Hung; Fang, Yen-Hsin; Cho, Kuan-Hung; Chien, Wei-Lin; Wang, Wei-Ting; Wu, Tzu-Wei; Lin, Ching-Po; Fu, Wen-Mei; Shen, Che-Kun James | The Journal of Experimental Medicine 207(8), 1661-1673 | |||
10 | 2010 | JNK-mediated turnover and stabilization of the transcription factor p45/NF-E2 during differentiation of murine erythroleukemia cells | Lee, T. L.; Shyu, Y. C.; Hsu, P. C.; Wen, S. C.; Hsiao, W. Y.; Chang, C. W.; Tsai, M. D. ; Shen, C. -K. J. | Proceedings of the national academy of sciences of the United States of America 107(1), 52-57 | |||
11 | 2010 | Developmental silencing of the humanζglobin gene expression is mediated by the transcriptional repressor RREB1 | Chen, R. -L.; Chou, Y. -C.; Lan, Y. -J.; Huang, T. -S.; Shen, C. -K. J. | Journal of Biological Chemistry 285, 10189-10197 | |||
12 | 2009 | Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis | Hou, Shin-Chen; Chan, Li-Wei; Chou, Yu-Chi ; Su, Ching-Yuan; Chen, Xin; Shih, Yen-Ling; Tsai, Pei-Chun; Shen, C. -K. James ; Yan, Yu-Ting | FEBS Letters 583(17), 2765-2771 | |||
13 | 2009 | Structural insights into TDP-43 in nucleic-acid binding and domain interactions | Kuo, P H; Doudeva, L. G.; Wang, Y. -T.; Shen, C. -K. J. ; Yuan, H. S. | Nucleic Acids Research 37(6), 1799-1808 | |||
14 | 2009 | Asymmetric expression patterns of brain transthyretin in normal mice and a transgenic mouse model of Alzheimer's disease | Tsai, K. -J.; Yang, C. -H.; Lee, P. -C.; Wang, W. -T.; Chiu, M. -J.; Shen, C. -K. J. | Neuroscience 159, 638-46 | |||
15 | 2009 | TDP-43, A Neuro-Pathosignature Factor, Is Essential for Early Mouse Embryogenesis. | Wu, L. S.; Cheng, W. C.; Hou, S. C.; Yan, Y. T.; Jiang, S. T.; Shen, C. K. J. | Genesis 48(1), 56-62 | |||
16 | 2008 | TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing | Bose, J. K.; Wang, I. -F.; Li, H. ; Tarn, W. -Y. ; Shen, C. -K. J. | J Biol Chem 283, 28852-28859 | |||
17 | 2008 | TDP -43, the signature protein of FTLD-U, is a neuronal activity-responsive factor | Wang, I. F.; Wu, L. S.; Chang, H. Y.; Chiou, G. Y.; Shen, C. K. J. | J. Neurochem 105, 797-806 | |||
18 | 2008 | TDP-43: an emerging new player in neurodegenerative diseases | Wang, I. -F.; Wu, L. -S.; Shen, C. -K. J. | Trends Mol Med. 14, 479-485 | |||
19 | 2007 | Epigenetic regulation of the Drosophila chromosome 4 by the histone H3K9 methyltransferase dSETDB1 | Tzeng, T. Y.; Lee, C. H.; Chan, L. W.; Shen, C. K. J. | Proceedings of the national academy of sciences of the United States of America 104, 12691-12696 | |||
20 | 2007 | G-CSF rescues the memory impairment of animal models of Alzheimer’s disease | Tsai, K. J.; Tsai, Y. C.; Shen, C. K. J. | J Exp Med 204, 1273-1280 | |||
21 | 2007 | Rate of Evolution in Brain-Expressed Genes in Humans and Other Primates | Wang, H. Y.; Chien, H. C.; Osada, N.; Hashimoto, K.; Sugano, S.; Gojobori, T.; Chou, C. K.; Tsai, S. F.; Tang, H.; Wu, C. I.; Shen, C. K. J. | PLOS Biology 5(2), e13 | |||
22 | 2006 | Proliferin enhances microvilli formation and cell growth of neuroblastoma cells | Wang, J. W.; Jiang, Y. N.; Huang, C. Y.; Huang, P. Y.; Huang, M. C.; Cheng, W. T. K.; Shen, C. K. J. ; Ju, Y. T. | Neuroscience Research 56, 80-90 | |||
23 | 2006 | Actin-based modeling of a transcriptionally competent nuclear substrcuture induced by transcription inhibition | Wang, I. F.; Chang, H. Y.; Shen, C. K. J. | Exp Cell Res 312, 3796-3807 | |||
24 | 2005 | DNA methyltransferase dDnmt2 and Drosophila longevity | Lin, M. J.; Tang, L. Y.; Reddy, M. N.; Shen, C. K. J. | J Biol Chem 280, 861-864 | |||
25 | 2005 | Substitution rate and structural divergence of 5'UTR evolution:comparative analysis between human and cynomolgus monkey cDNAs | Osada, N.; Hirata, M.; Tanuma, R.; Kusuda, J.; Hida, M.; Suzuki, Y.; Sugano, S.; Gojobori, T.; Shen, C. K. J. ; Wu, C. I.; Hashimoto, K. | Mol Biol Evol 22, 1976-1982 | |||
26 | 2005 | Sumoylation of p45/NF-E2: nuclear positioning and transcriptional activation of the mammalian beta-like globin gene locus | Shyu, Y. C.; Lee, T. L.; Ting, C. Y.; Wen, S. C.; Hsieh, L. J.; Li, Y. C.; Hwang, J. L.; Lin, C. C.; Shen, C. K. J. | Mol Cell Biol 25, 10365-10378 | |||
27 | 2004 | DNA methyltransferase Dnmt1 and mismatch repair | Wang, K. Y.; Shen, C. K. J. | Oncogene 23, 7898-7902 | |||
28 | 2004 | Structural diversity and functional implications of the eukaryotic TDP gene family | Wang, H. Y.; Wang, I. F.; Bose, J.; Shen, C. K. J. | Genomics 83, 130-139 | |||
29 | 2003 | A candidate gene for Drosophila genome methylation | Reddy, M. Narsa; Tang, L. Y.; Lee, T. L.; Shen, C. K. J. | Oncogene 22, 6301-6303 | |||
30 | 2003 | Erythroid gene suppression by NF-kappa B | Liu, J. J.; Hou, S. C.; Shen, C. K. J. | J Biol Chem 278, 19534-19540 | |||
31 | 2003 | Eukaryotic methyl-CpG-binding domain proteins and chromatin modification | Hung, M. S.; Shen, C. K. J. | Eukaryot Cell 2, 841-846 | |||
32 | 2003 | Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria parasites. | Wang, H. Y.; Tang, H.; Shen, C. K. J. ; Wu, C. I. | Mol Biol Evol 20, 1795-1804 | |||
33 | 2003 | The eukaryotic DNMT2 genes encode a new class of cytosine-5 DNA methyltransferases | Tang, L. Y.; Reddy, M. N.; Rasheva, V.; Lee, T. L.; Lin, M. J.; Hung, M. S.; Shen, C. K. J. | J Biol Chem 278, 33613-33616 | |||
34 | 2002 | Higher order arrangement of the eukaryotic nuclear bodies | Wang, I. F.; Reddy, N. M.; Shen, C. K. J. | Proceedings of the national academy of sciences of the United States of America 99, 13583-13588 | |||
35 | 2002 | NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor | Gavva, N. R.; Wen, S. C.; Daftari, P.; Moniwa, M.; Yang, W. M.; Yang-Feng, L. P.; Seto, E.; Davie, J. R.; Shen, C. K. J. | Genomics 79, 423-431 | |||
36 | 2001 | Human ITCH is a coregulator of the hematopoietic transcription factor NF-E2 | Chen, X.; Wen, S.; Fukuda, M. N.; Gavva, N. R.; Hsu, D.; Akama, T. O.; Yang-Feng, T.; Shen, C. K. J. | Genomics 73, 238-241 | |||
37 | 2001 | Sharing duties in the family | Shen, C. K. J. | Genome Res 11, 1615 | |||
38 | 2000 | Transcriptional repression by Drosophila methyl-CpG-binding proteins | Roder, K.; Hung, M. S.; Lee, T. L.; Lin, T. Y.; Xiao, H.; Isobe, K. I.; Juang, J. L.; Shen, C. K. J. | Mol Cell Biol 20, 7401-7409 | |||
39 | 2000 | One-codon alternative splicing of the CpG MTase Dnmt1 transcript in mouse somatic cells | Lin, M. J.; Lee, T. L.; Hsu, D. W.; Shen, C. K. J. | FEBS Lett 469, 101-104 | |||
40 | 2000 | Loading of DNA-binding factors to an erythroid enhancer | Wen, S. C.; Roder, K.; Hu, K. Y.; Rombel, I.; Gavva, N. R.; Daftari, P.; Kuo, Y. Y.; Wang, C. ; Shen, C. K. J. | Molecular and Cellular Biology 20(6), 1993-2003 | |||
41 | 1999 | Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissues | Hsu, D. W.; Lin, M. J.; Lee, T. L.; Wen, S. C.; Chen, X.; Shen, C. K. J. | Proceedings of the national academy of sciences of the United States of America 96, 9751-9756 | |||
42 | 1999 | Drosophila proteins related to vertebrate DNA (5-cytosine) methyltransferases | Hung, M. S.; Karthikeyan, N.; Huang, B.; Koo, H. C.; Kiger, J.; Shen, C. K. J. | Proceedings of the national academy of sciences of the United States of America 96, 11940-11945 | |||
43 | 1998 | Derepression of human embryonic zeta-globin promoter by a locus-control region sequence | Huang, B. L.; Fan-Chiang, I. R.; Wen, S. C.; Koo, H. C.; Kao, W. Y.; Gavva, N. R.; Shen, C. K. J. | Proceedings of the national academy of sciences of the United States of America 95, 14669-14674 | |||
44 | 1988 | Structure and expression of the human theta 1 globin gene | Hsu, S. L.; Marks, J.; Shaw, J. P.; Tam, M.; Higgs, D. R.; Shen, C. C.; Shen, C. K. J. | Nature 331, 94-96 |