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Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
12022Human rs75776403 Polymorphism Links Differential Phenotypic and Clinical Outcomes to a CLEC18A p.T151M-Driven MultiomicsHsu, YW; Huang, H, CH; Huang, WC ; Yeh, YH; Hsiao, CD ; Chang, WC; Hsieh, SL JOURNAL OF BIOMEDICAL SCIENCE 29(1), 43
22022The lipid components of high-density lipoproteins (HDL) are essential for the binding and transportation of antimicrobial peptides in human serumTang, Wen-Hung; Wang, Shi-Han; Wang, Chiu-Feng; Mou, Yun ; Lin, Min-Guan; Hsiao, Chwan-Deng ; Liao, You-Di Scientific Reports 12, 2576
32021SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infectionTsai, Tsung-Yu; Huang, Ming-Ting; Sung, Pei-Shan; Peng, Cheng-Yuan; Tao, Mi-Hua ; Yang, Hwai-I ; Chang, Wei-Chiao; Yang, An-Suei ; Yu, Chung-Ming; Lin, Ya-Ping; Bau, Ching-Yu; Huang, Chih-Jen; Pan, Mei-Hung; Wu, Chung-Yi ; Hsiao, Chwan-Deng ; Yeh, Yi-Hung; Duan, Shiteng; Paulson, James, C; Hsieh, Shie-Liang Journal of Clinical Investigation 131(11), e141965
42016Exploring the Mechanism Responsible for Cellulase Thermostability by Structure-Guided RecombinationChia-Jung Chang; Cheng-Chung Lee; Yueh-Te Chan; Devin L. Trudeau; Mei- Huey Wu; Chih-Hsuan Tsai; Su-May Yu ; Tuan-Hua David Ho ; Andrew H.-J. Wang ; Chwan-Deng Hsiao ; Frances H. Arnold; Yu-Chan Chao PLoS ONE 11 (3):e0147485
52015ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer DevelopmentFang, L.; Lu, W.; Choi, H.H; Yeung, S.J; Tung, J.-Y.; Hsiao, C.-D. ; Fuentes-Mattei, E.; Menter, D; Chen, C.; Wang, .L; Wang, J.; Lee, M.H.CANCER CELL 10;28(2):183-197
62014Structural and functional characterization of ybr137wp implicates its involvement in the targeting of tail-anchored proteins to membranesYeh, YH; Lin, TW; Li, YC; Tung, JY; Lin, CY; Hsiao, CD Molecular and cellular biology 34(24), 4500-4512
72014Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA elementLi, YC; Chang, CK; Chang, CF; Cheng, YH; Fang, PJ; Yu, T; Chen, SC; Li, YC; Hsiao, CD ; Huang, THNucleic acids research 42(13), 8777-88
82014Interactions That Influence the Binding of Synthetic Heparan Sulfate Based Disaccharides to Fibroblast Growth Factor-2Li, YC; Ho, IH; Ku, CC; Zhong, YQ; Hu, YP; Chen, ZG; Chen, CY; Lin, WC; Zulueta, MM; Hung, SC ; Lin, MG; Wang, CC ; Hsiao, CD ACS chemical biology 9(8), 1712-1717
92012Crystal Structure of a Membrane-embedded H+-Translocating PyrophosphataseLin, S. -M.; Tsai, J. -Y.; Hsiao, C. -D. ; Huang, Y. -T.; Chiu, C. -L.; Liu, M. -H.; Tung, Y. -Y.; Liu, T. -H.; Pan, R. -L.; Sun, Y. -J.NATURE 484, 399-403
102012Structure of the catalytic domain of the Clostridium thermocellum cellulase CelTKesavulu, MM; Tsai, JY; Lee, HL; Liang, PH ; Hsiao, CD Acta Crystallographica Section D: Biological Crystallography D68, 310-320
112012Crystal structure of KpNFeoB/KpFeoC complex and the roles of FeoC in the regulation of Fe2+ transport by the bacterial Feo systemHung, K.-W.; Tsai, J.-Y.; Juan, T.-H.; Hsu, Y.-L.; Hsiao, C.-D. ; Huang, T. H.J. of Bacteriol. 194, 6518-6526
122012Crystal structures of Helicobacter pylori uridylate kinase: insight into the product UDP releaseChu, C. -H.; Liu, M. -H.; Chen, P. -C.; Lin, M. -H.; Li, Y. -C.; Hsiao, C. -D. ; Sun, Y. -J.Acta Cryst. D. 68, 773-783
132012R432 is a key residue for the multiple functions of Ndt80p in Candida albicansYang, Y. -L.; Wang, C. -W.; Leaw, S. -N.; Chang, T. -P.; Wang, I. -C.; Chen, C. -G.; Fan, J. -C.; Tseng, K. -Y.; Huang, S. -H.; Chen, C. -Y.; Hsiao, T. -Y.; Hsiung, C. -A.; Chen, C. -T.; Hsiao, C. -D. ; Lo, H. -J.Cell Mol. Life Sci. 69, 1011-1023
142012Interaction Surface and Topology of Get3/Get4/Get5, a Complex Involved in Targeting Tail-Anchored Proteins to the Endoplasmic ReticulumChang, Y. -W.; Lin, T. -W.; Li, Y. -C.; Huang, Y. -S.; Sun, Y. -J.; Hsiao, C. -D. J. Biol. Chem. 287, 4783-4789
152012Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformationWei, S. -Y.; Lou, Y. -C.; Tsai, J. -Y.; Ho, M. -R. ; Rajasekaran, M.; Liu, H. -W.; Tai, J. -H.; Hsiao, C. -D. ; Chen, C. Nucleic Acids Research 40(1),  449-460
162012Crystal Structure of DnaK Protein Complexed with Nucleotide Exchange Factor GrpE in DnaK Chaperone SystemWu, C. -C.; Naveen, V.; Chang, Y. -W.; Chien, C. -H.; Hsiao, C. -D. J. Biol. Chem. 287, 21461-21470
172011Activity and function of rabbit muscle-specific creatine kinase at low temperature by mutation at gly268 to asn268Wu, C. -L.; Li, Y. -H.; Lin, H. -C.; Yeh, Y. -H.; Yan, H. -Y.; Hsiao, C. -D. ; Hui, C. -F.; Wu, J. -L.Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology 158, 189-198
182011Mutations Altering the Interplay between GkDnaC Helicase and DNA Reveal an Insight into Helicase UnwindingLo, Y. -H.; Liu, S. -W.; Sun, Y. -J.; Li, H. -W; Hsiao, C. -D. PLoS One 6(12), e29016
192010Crystal Structure of Get4/Get5 Complex and Its Interactions with Sgt2, Get3 and Ydj1Chang, Y. -W.; Chuang, Y. -C.; Ho, Y. -C.; Cheng, M. -Y.; Sun, Y. -J.; Hsiao, C. -D. ; Wang, C.J. Biol. Chem. 285, 9962-9970
202010SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and -2Peck, B.; Chen, C. -Y.; Ho, K. -K.; Frusia, P. D.; Yatt, S. S.; Coombes, R. C.; Fuchter, M. J.; Hsiao, C. -D. ; Lam, E. W. -F.Mol. Cancer Ther. 9, 844-855
212010Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoBHung, K. -W.; Chang, Y. -W.; Eng, E. T.; Chen, J. -H.; Chen, Y. -C.; Sun, Y. -J.; Hsiao, C. -D. ; Dong, G.; Unger, V. M.; Huang, T. -HJ. Struct Biol. 170, 501-512
222009Molecular Interplay between the Replicative Helicase DnaC and its Loader Protein DnaI from Geobacillus kaustophilus.Tsai, K.-L.; Lo, Y.-H.; Sun, Y.-J.; Hsiao, C.-D. J Mol Biol 393(5), 1056-1069
232009The crystal structure of a replicative hexameric helicase DnaC and its complex with single-stranded DNA.Lo, Y. -H.; Tsai, K. -L.; Sun, Y. -J.; Chen, W. -T.; Huang, C. -Y.; Hsiao, C. -D. Nucleic Acids Res 37, 804-814
242008Crystal structure of the 70-kDa heat shock proteins in domain disjoining conformationChang, Y-W.; Sun, Y-J.; Wang, C. ; Hsiao, C-D. Journal of Biological Chemistry 283(22), 15502-15511
252008ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradationYang, J. Y.; Zong, C. S.; Xia, W.; Yamaguchi, H.; Ding, Q.; Xie, X.; Lang, J. Y.; Lai, C. C.; Chan, C. J.; Huang, G W. C.; Huang, H.; Kuo, H. P.; Lee, D. F.; Li, L. Y.; Lien, H. C.; Cheng, X.; Chang, K. J.; Hsiao, C. D. ; Tsai, F. J.; Tsai, C. H.; Sahin, A. A.; Muller, W. J.; Mills, G. B.; Yu, D.; Gortobagyi, G. N.; Hung, M. C.NATURE CELL BIOLOGY 10, 138-148
262007Small Ubiquitin-like Modifier Modification Regulates the DNA Binding Activity of Glial Cell Missing Drosophila Homolog aChou, CC; Chang, C; Liu, JH; Chen, LF; Hsiao, CD ; Chen, H Journal of Biological Chemistry 282(37), 27239-27249
272007Toc GTPasesLi, H. M.; Kesavulu, M. M.; Su, P. H.; Yeh, Y. H.; Hsiao, C. D. J Biomed Sci 14, 505-508
282007Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modificationTsai, K. L.; Sun, Y. J.; Huang, C. Y.; Yang, J. Y.; Hung, M. C.; Hsiao, C. D. Nucleic Acids Res 35, 6984-6994
292007Structure of the SARS Coronavirus Nucleocapsid Protein RNA-binding Dimerization Domain Suggests a Mechanism for Helical Packaging of Viral RNAChen, C. Y.; Chang, C. K.; Bai, H. I.; Riang, L.; Hsiao, C. D. ; Huang, T. H.J Mol Biol 368, 1075-1086
302007Dimerization is important for the GTPase activity of chloroplast translocon components atToc33 and psToc159Yeh, Y. H.; Kesavulu, M. M.; Li, H. M.; Wu, S. Z.; Sun, Y. J.; Konozy, E. H. E.; Hsiao, C. D. J Biol Chem 282, 13845-13853
312006Crystal structure of the human FOXK1a/DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteinsTsai, K. L.; Huang, C. Y.; Chang, C. H.; Sun, Y. J.; Chuang, W. J.; Hsiao, C. D. J Biol Chem 281, 17400-17409
322006Complexed crystal structure of replication restart primosome protein PriB reveals a novel single-stranded DNA-binding modeHuang, C. Y.; Hsu, C. H.; Sun, Y. J.; Wu, H. N.; Hsiao, C. D. Nucleic Acids Research 34, 3878-3886
332006Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin. The sulfatide.cardiotoxin complex structure in a membrane-like environment suggests a lipid-dependent cell-penetrating mechanism for membrane binding polypeptidesWang, C. H.; Liu, J. H.; Lee, S. C.; Hsiao, C. D. ; Wu, W. G.J Biol Chem 281, 656-667 (co-corresponding author)
342004Crystal structure of PriB, a primosomal DNA replication protein of Escherichia coliLiu, J. H.; Chang, T. W.; Huang, C. Y.; Chen, S. U.; Wu, H. N.; Chang, M. C.; Hsiao, C. D. J Biol Chem 279, 50465-50471
352003Crystal structure of the C-terminal 10-kDa subdomain of Hsc70Chou, C. C.; Forouhar, F.; Yeh, Y. H.; Shr, H. L.; Wang, C.; Hsiao, C. D. J Biol Chem 278, 30311-30316
362003Structural basis of membrane-induced cardiotoxin A3 oligomerizationForouhar, F.; Huang, W. N.; Liu, J. H.; Chien, K. Y.; Wu, W. G.; Hsiao, C. D. J Biol Chem 278, 21980-21988
372002Characterization of the L399P and R447G mutants of hsc70: the decrease in refolding activity is correlated with an increase in the rate of substrate dissociationHu, S. M.; Liang, P. H. ; Hsiao, C. D. ; Wang, C. Arch Biochem Biophys 407(1), 135-141
382002Expression of selenomethionyl proteins in a prototrophic strain of Escherichia coliLiu, L. F.; Liu, Y. C.; Hsieh, C. H.; Tam, T. C.; Chuang, C. H.; Hsiao, C. D. ; Tam, M. F. Analytical Biochemistry 307(1), 173-176
392002Crystal structure of pea Toc34, a novel GTPase of the chloroplast protein transloconSun, Y. J.; Forouhar, F.; Li, H. M. ; Tu, S. L. ; Yeh, Y. H.; Kao, S.; Shr, H. L.; Chou, C. C.; Chen, C.; Hsiao, C. D. NATURE STRUCTURAL BIOLOGY 9, 95-100
402001The crystal structure of a novel mammalian lectin, Ym1, suggests a saccharide binding siteSun, Y. J.; Chang, N. C.; Hung, S. I.; Chang, A. C.; Chou, C. C.; Hsiao, C. D. J Biol Chem 276, 17507-17514
412001Crystallization and preliminary X-ray diffraction analysis of the 10 kDa C-terminal subdomain of 70 kDa heat-shock cognate proteinChou, C. C.; Wang, C.; Sun, Y. J.; Shr, H. L.; Hsiao, C. D. Acta Crystallogr D Biol Crystallogr 57, 1928-1930
422001The effect of mutating arginine-469 on the substrate binding and refolding activities of 70-kDa heat shock cognate proteinChang, T. C.; Hsiao, C. D. ; Wu, S. J.; Wang, C. Archives of Biochemistry and Biophysics 386(1), 30-36
432000Tyr115, Gln165 and Trp209 contribute to the 1,2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1Chern, M. K.; Wu, T. C.; Hsieh, C. H.; Chou, C. C.; Liu, L. F.; Kuan, I. C.; Yeh, Y. H.; Hsiao, C. D. ; Tam, M. F. Journal of Molecular Biology 300(5), 1257-1269
442000The crystal structure of phosphoglucose isomerase/autocrine motility factor/neuroleukin complexed with its carbohydrate phosphate inhibitors suggests its substrate/receptor recognitionChou, C. C.; Sun, Y. J.; Meng, M.; Hsiao, C. D. J Biol Chem 275, 23154-23160
451999Specific interaction of the 70-kDa heat shock cognate protein with the tetratricopeptide repeatsLiu, F. H. ; Wu, S. J.; Hu, S. M.; Hsiao, C. D. ; Wang, C. The Journal of biological chemistry 274(48), 34425-34432
461999The crystal structure of a multifunctional protein: phosphoglucose isomerase/autocrine motility factor/neuroleukinSun, Y. J.; Chou, C. C.; Chen, W. S.; Wu, R. T.; Meng, M.; Hsiao, C. D. Proc Natl Acad Sci U S A 96, 5412-5417
471998The three-dimensional structure of an avian class-mu glutathione S-transferase, cGSTM1-1 at 1.94 A resolutionSun, Y. J.; Kuan, I. C.; Tam, M. F. ; Hsiao, C. D. Journal of Molecular Biology 278(1), 239-252
481998The structure of glutamine-binding protein complexed with glutamine at 1.94 A resolution: comparisons with other amino acid binding proteinsSun, Y. J.; Rose, J.; Wang, B. C.; Hsiao, C. D. J Mol Biol 278, 219-229
491997Crystal structure of cardiotoxin V from Taiwan cobra venom: pH-dependent conformational change and a novel membrane-binding motif identified in the three-finger loops of P-type cardiotoxinSun, Y. J.; Wu, W. G.; Chiang, C. M.; Hsin, A. Y.; Hsiao, C. D. Biochemistry 36, 2403-2413
501997Expression, purification, and crystallization of two isozymes of 6-phosphoglucose isomerase of Bacillus stearothermophilusHsiao, C. D. ; Chou, C. C.; Hsiao, Y. Y.; Sun, Y. J.; Meng, M.J Struct Biol 120, 196-200
511996Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genesChien, C. T.; Hsiao, C. D. ; Jan, L. Y.; Jan, Y. N.Proc Natl Acad Sci U S A 93, 13239-13244
521996The crystal structure of glutamine-binding protein from Escherichia coliHsiao, C. D. ; Sun, Y. J.; Rose, J.; Wang, B. C.J Mol Biol 262, 225-242
531995Amino acid sequencing, molecular cloning and modelling of the chick liver class-theta glutathione S-transferase CL1Hsiao, C. D. ; Martsen, E. O.; Lee, J. Y.; Tsai, S. P.; Tam, M. F. Biochemical Journal 312(1), 91-98
541994Modification of glutathione S-transferase 3-3 mutants with 2-(S-glutathionyl)-3,5,6-trichloro-1,4-benzoquinone. Identification of the C-terminal tryptic fragment as part of the H-site and evidence that 2-(S-glutathionyl)-3,5,6-trichloro-1,4-benzoquinone is not specific for cysteine labellingHong, J. L.; Liu, L. F.; Wang, L. Y.; Tsai, S. P.; Hsieh, C. H.; Hsiao, C. D. ; Tam, M. F. Biochemical Journal 304(3), 825-831