Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
2008 | A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence | Liu, CI; Liu, GY; Song, Y; Yin, F; Hensler, ME; Jeng, WY; Nizet, V; Wang, AHJ ; Oldfield, E | Science 319(5868), 1391-1394 | | | |
2007 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases | Guo, RT; Cao, R; Liang, PH ; Ko, TP; Chang, TH; Hudock, MP; Jeng, WY; Chen, CK; Zhang, Y; Song, Y; Kuo, CJ; Yin, F; Oldfield, E; Wang, AHJ | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(24), 10022-10027 | | | |
2015 | Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. | Han, X; Chen, CC; Kuo, CJ; Huang, CH; Zheng, Y; Ko, TP; Zhu, Z; Feng, X; Wang, K; Oldfield, E; Wang, AH ; Liang, PH ; Guo, RT; Ma, Y | Proteins 83(1), 37-45 | | | |
2008 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. | Chen, C K-M; Hudock, MP; Zhang, Y; Guo, RT; Cao, R; No, JH; Liang, PH ; Ko, TP; Chang, TH; Chang, SC; Song, Y; Axelson, J; Kumar, A; Wang, AHJ ; Oldfield, E | Journal of medicinal chemistry 51(18), 5594-5607 | | | |
2009 | Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. | Song, Y; Liu, CI; Lin, FY; No, JH; Hensler, M; Liu, YL; Jeng, WY; Low, J; Liu, GY; Nizet, V; Wang, AHJ ; Oldfield, E | Journal of medicinal chemistry 52(13), 3869-80 | | | |
2012 | Insights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different Complexes. | Ren, F; Ko, TP; Feng, X; Huang, CH; Chan, HC; Hu, Y; Wang, K; Ma, Y; Liang, PH ; Wang, AH; Oldfield, E; Guo, RT | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 51(17), 4157-4160 | | | |
2009 | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. | Zhang, Y; Cao, R; Yin, F; Hudock, MP; Guo, RT; Krysiak, K; Mukherjee, S; Gao, YG; Robinson, H; Song, Y; No, JH; Bergan, K; Leon, A; Cass, L; Goddard, A; Chang, TK; Lin, FY; Van Beek, E; Papapoulos, S; Wang, AHJ ; Kubo, T; Ochi, M; Mukkamala, D; Oldfield, E | Journal of the American Chemical Society 131(14), 5153-62 | | | |
2010 | Mechanism of action and inhibition of dehydrosqualene synthase. | Lin, FY; Liu, CI; Liu, YL; Zhang, Y; Wang, K; Jeng, WY; Ko, TP; Cao, R; Wang, AHJ ; Oldfield, E | Proceedings of the National Academy of Sciences of the United States of America 107(50), 21337-21342 | | | |
2016 | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. | Zhang, L; Chen, CC; Ko, TP; Huang, JW; Zheng, Y; Liu, W; Wang, I; Malwal, SR; Feng, X; Wang, K; Huang, CH; Hsu, STD ; Wang, AH ; Oldfield, E; Guo, RT | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55(15), 4716-20 | | | |
1981 | Protein crystals, membrane proteins and membrane lipids. Recent advances in the study of their static and dynamic structures using nuclear magnetic resonance spectroscopic techniques | Oldfield, E; Janes, N; Kinsey, R; Kintanar, A; Lee, RW; Rothgeb, TM; Schramm, S; Skarjune, R; Smith, R; Tsai, MD | Biochemical Society Symposium (46), 155-181 | | | |
2014 | Squalene synthase as a target for Chagas disease therapeutics. | Shang, N; Li, Q; Ko, TP; Chan, HC; Li, J; Zheng, Y; Huang, CH; Ren, F; Chen, CC; Zhu, Z; Galizzi, M; Li, ZH; Rodrigues-Poveda, CA; Gonzalez-Pacanowska, D; Veiga-Santos, P; de Carvalho, TM; de Souza, W; Urbina, JA; Wang, AH ; Docampo, R; Li, K; Liu, YL; Oldfield, E; Guo, RT | PLoS pathogens 10(5), e1004114 | | | |
2008 | Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. | Cao, R; Chen, CK; Guo, RT; Wang, AHJ ; Oldfield, E | Proteins 73(2), 431-9 | | | |
2016 | Structures of Trypanosome Vacuolar Soluble Pyrophosphatases: Antiparasitic Drug Targets. | Yang, Y; Ko, TP; Chen, CC; Huang, G; Zheng, Y; Liu, W; Wang, I; Ho, MR ; Hsu, STD ; O’Dowd, B; Huff, HC; Huang, CH; Docampo, R; Oldfield, E; Guo, RT | ACS chemical biology 11(5), 1362-1371 | | | |