Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
2005 | 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors | Brik, A.; Alexandratos, J.; Lin, Y. C.; Elder, J. H.; Olson, A. J.; Wlodawer, A.; Goodsell, D. S.; Wong, C. H. | Chembiochem 6, 1167-1169 | | | |
2008 | A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant | Giffin, M. J.; Heaslet, H.; Brik, A.; Lin, Y. -C.; Cauvi, G.; Wong, C. -H.; McRee, D. E.; Elder, J. H.; Stout, C. D.; Torbett, B. E. | J. Med. Chem 51(20), 6263-6270 | | | |
2000 | Alteration of substrate and inhibitor specificity of feline immunodeficiency virus protease | Lin, Y. C.; Beck, Z.; Lee, T.; Le, V. D.; Morris, G. M.; Olson, A. J.; Wong, C. H.; Elder, J. H. | J Virol 74, 4710-4720 | | | |
1998 | Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo | Lee, T.; Laco, G. S.; Torbett, B. E.; Fox, H. S.; Lerner, D. L.; Elder, J. H.; Wong, C. H. | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95, 939-944 | | | |
2003 | Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases | Mak, C. C.; Brik, A.; Lerner, D. L.; Elder, J. H.; Morris, G. M.; Olson, A. J.; Wong, C. H. | BIOORGANIC & MEDICINAL CHEMISTRY 11, 2025-2040 | | | |
2001 | Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue | Mak, C. C.; Le, V. D.; Lin, Y. C.; Elder, J. H.; Wong, C. H. | Bioorg Med Chem Lett 11, 219-222 | | | |
1999 | Development of a new type of protease inhibitors, efficacious against FIV and HIV variants | Lee, T. Y.; Le, V. D.; Lim, D. Y.; Lin, Y. C.; Morris, G. M.; Wong, A. L.; Olson, A. J.; Elder, J. H.; Wong, C. H. | J Am Chem Soc 121, 1145-1155 | | | |
2006 | Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates | Liang, F. S.; Brik, A.; Lin, Y. C.; Elder, J. H.; Wong, C. H. | Bioorganic & medicinal chemistry 14, 1058-1062 | | | |
1999 | HIV protease inhibitors with small P3 residues. Broad-based Protease Inhibitors Efficacious Against FIV, SIV | Lee, T.; Elder, J. H.; Wong, C. H. | US Patent (Allowed) | | | |
2003 | Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors | Brik, A.; Muldoon, J.; Lin, Y. C.; Elder, J. H.; Goodsell, D. S.; Olson, A. J.; Fokin, V. V.; Sharpless, K. B.; Wong, C. H. | Chembiochem 4, 1246-1248 | | | |
1995 | Selectivity in the Inhibition of Hiv and Fiv Protease - Inhibitory and Mechanistic Studies of Pyrrolidine-Containing Alpha-Keto Amide and Hydroxyethylamine Core Structures | Slee, D. H.; Laslo, K. L.; Elder, J. H.; Ollmann, I. R.; Gustchina, A.; Kervinen, J.; Zdanov, A.; Wlodawer, A.; Wong, C. H. | J Am Chem Soc 117, 11867-11878 | | | |
2000 | Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease | Li, M.; Morris, G. M.; Lee, T.; Laco, G. S.; Wong, C. H.; Olson, A. J.; Elder, J. H.; Wlodawer, A.; Gustchina, A. | Proteins 38, 29-40 | | | |
2001 | Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine | Le, V. D.; Mak, C. C.; Lin, Y. C.; Elder, J. H.; Wong, C. H. | BIOORGANIC & MEDICINAL CHEMISTRY 9, 1185-1195 | | | |
2001 | Viral evolution in response to the broad-based retroviral protease inhibitor TL-3 | Buhler, B.; Lin, Y. C.; Morris, G.; Olson, A. J.; Wong, C. H.; Richman, D. D.; Elder, J. H.; Torbett, B. E. | J Virol 75, 9502-9508 | | | |