Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
2008 | A critical evaluation of adenosine A2A receptors as potentially ““druggable”” targets in Huntington's disease | Popoli, P.; Blum, D.; Domenici, M. R.; Burnouf, S.; Chern, Y. | CURRENT PHARMACEUTICAL DESIGN 14(15), 1500-1511 | | | |
2015 | Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis | Liu, Y. J.; Lee, L. M.; Lai, H. L.; Chern, Y. | FEBS letters 589(4), 432-439 | | | |
2015 | Activation of AMP-activated protein kinase alpha1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis | Liu, Y. J.; Ju, T. C.; Chen, H. M.; Jang, Y. S.; Lee, L. M.; Lai, H. L.; Tai, H. C.; Fang, J. M.; Lin, Y. L.; Tu, P. H.; Chern, Y. | Human molecular genetics 24:787-801. | | | |
1997 | Activation of phosphodiesterase IV during desensitization of the A2A adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells | Chang, Y. H.; Conti, M.; Lee, Y. C.; Lai, H. L.; Ching, Y. H.; Chern, Y. | J Neurochem 69, 1300-1309 | | | |
2001 | Activation of protein kinase A and atypical protein kinase C by A(2A) adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells | Huang, N. K.; Lin, Y. W.; Huang, C. L.; Messing, R. O.; Chern, Y. | J Biol Chem 276, 13838-13846 | | | |
2004 | An Important functional role of the N terminus domain of type VI adenylyl cyclase (ACVI) in Gia-mediated inhibition | Kao, Y. Y.; Lai, H. L.; Hwang, M. J.; Chern, Y. | J Biol Chem 279, 34440-34448 | | | |
2007 | Aspects of the general biology of adenosine A2A signaling | Fredholm, B. B.; Chern, Y.; Franco, R.; Sitkovsky, M. | Prog Neurobiol 83(5), 263-276 | | | |
2005 | CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model | Chou, SY; Lee, YC; Chen, HM; Chiang, MC; Lai, HL; Chang, HH; Wu, YC; Sun, CN; Chien, CL; Lin, YS; Wang, SC; Tung, YY; Chang, C; Chern, Y. | Journal of Neurochemistry 93, 310-320 | | | |
1996 | Characterization of the rat A2a adenosine receptor gene | Chu, Y. Y.; Tu, K. H.; Lee, Y. C.; Kuo, Z. J.; Lai, H. L.; Chern, Y. | DNA Cell Biol 15, 329-337 | | | |
2003 | Characterization of the rat A2A adenosine receptor gene: a 4.8-kb promoter-proximal DNA fragment confers selective expression in the central nervous system. | Lee, Y-C; Chien, C-L; Sun, C-N; Chiang, MC; Huang, C-L; Huang, N-K; Lai, H-L; Lin, Y-S; Chiou, S-Y; Liao, W-L; Liu, F-C; Wang, L; Tai, M-H; Lin, T-N; Chern, Y. | Eur. J. Neurosci. 18, 1786-1796 | | | |
1996 | Circadian rhythm in the Ca(2+)-inhibitable adenylyl activity of the rat striatum | Chern, Y.; Lee, E. H.; Lai, H. L.; Wang, H. L.; Lee, Y. C.; Ching, Y. H. | FEBS Lett 385, 205-208 | | | |
2005 | CREB contributes to suppression of the A2A adenosine receptor promoter by mutant Huntingtin with expanded polyglutamine residues | Chiang, M. C.; Lee, Y. C.; Huang, C. L.; Chern, Y. | J Biol Chem 280, 14331-14340 | | | |
2015 | Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease | Liu, K. Y.; Shyu, Y. C.; Barbaro, B. A.; Lin, Y. T.; Chern, Y.; Thompson, L. M.; James Shen, C. K.; Marsh, J. L. | Human molecular genetics 24(6)L 1602-1616 | | | |
1994 | Distribution and regulation of rab3C, a small molecular weight GTP-binding protein | Su, Y. C.; Kao, L. S.; Chu, Y. Y.; Liang, Y.; Tsai, M. H.; Chern, Y. | Biochem Biophys Res Commun 200, 1257-1263 | | | |
2007 | Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease | Chiang, M. C.; Chen, H. M.; Lee, Y. H.; Chang, H. H.; Wu, Y. C.; Soong, B. W.; Chen, C. M.; Wu, Y. R.; Liu, C. S.; Niu, D. M.; Wu, J. Y.; Chen, Y. T.; Chern, Y. | Hum Mol Genet 16(5), 483-498 | | | |
2012 | Energy Dysfunction in Huntington’s Disease: Insights from PGC-1α, AMPK, and CKB. | Ju, TC; Lin, YS; Chern, Y. | CELLULAR AND MOLECULAR LIFE SCIENCES 69(24), 4107-4120 | | | |
2002 | Essential role of cAMP-response element-binding protein activation by A2A adenosine receptors in rescuing the nerve growth factor-induced neurite outgrowth impaired by blockage of the MAPK cascade | Cheng, H. C.; Shih, H. M.; Chern, Y. | J Biol Chem 277, 33930-33942 | | | |
2008 | Expanded-polyglutamine Huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes | Chou, S. Y.; Weng, J. Y.; Lai, H. L.; Liao, F.; Sun, S. H.; Tu, P. H.; Dickson, D. W.; Chern, Y. | J Neurosci 28(13), 3277-3290 | | | |
1998 | Expression of type VI adenylyl cyclase in the central nervous system: implication for a potential regulator of multiple signals in different neurotransmitter systems | Liu, F. C.; Wu, G. C.; Hsieh, S. T.; Lai, H. L.; Wang, H. F.; Wang, T. W.; Chern, Y. | FEBS Lett 436, 92-98 | | | |
1992 | Four unique monoclonal antibodies to the putative receptor binding domain of erythropoietin inhibit the biological function of the hormone | Feldman, L.; Heinzerling, R.; Hillam, R. P.; Chern, Y.; Frazier, J. G.; Davis, K. L.; Sytkowski, A. J. | Exp Hematol 20, 64-68 | | | |