Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
2005 | 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors | Brik, A.; Alexandratos, J.; Lin, Y. C.; Elder, J. H.; Olson, A. J.; Wlodawer, A.; Goodsell, D. S.; Wong, C. H. | Chembiochem 6, 1167-1169 | | | |
2008 | A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant | Giffin, M. J.; Heaslet, H.; Brik, A.; Lin, Y. -C.; Cauvi, G.; Wong, C. -H.; McRee, D. E.; Elder, J. H.; Stout, C. D.; Torbett, B. E. | J. Med. Chem 51(20), 6263-6270 | | | |
2002 | A quick diversity-oriented amide-forming reaction to optimize P-subsite residues of HIV protease inhibitors | Brik, A.; Lin, Y. C.; Elder, J.; Wong, C. H. | Chem Biol 9, 891-896 | | | |
2003 | Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases | Mak, C. C.; Brik, A.; Lerner, D. L.; Elder, J. H.; Morris, G. M.; Olson, A. J.; Wong, C. H. | BIOORGANIC & MEDICINAL CHEMISTRY 11, 2025-2040 | | | |
2006 | Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates | Liang, F. S.; Brik, A.; Lin, Y. C.; Elder, J. H.; Wong, C. H. | Bioorganic & medicinal chemistry 14, 1058-1062 | | | |
2007 | Extended Sugar-Assisted Ligations: Development, Scope and Applications | Payne, R. J.; Ficht, S.; Tang, S.; Brik, A.; Yang, Y. -Y.; Case, D. A.; Wong, C. -H. | J. Am. Chem. Soc 129(44), 13527-13536 | | | |
2003 | HIV-1 protease: mechanism and drug discovery | Brik, A.; Wong, C. H. | Org Biomol Chem 1, 5-14 | | | |
2006 | Microtiter Plate Based Chemistry and In Situ Screening: A Useful Approach for Rapid Inhibitors Discovery | Brik, A.; Wu, C. Y.; Wong, C. H. | ORGANIC & BIOMOLECULAR CHEMISTRY 4, 1446-1457 | | | |
2004 | Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitos in Escherichia coli | Cheng, T. J.; Brik, A.; Wong, C. H.; Kan, C. C. | Antimicrob Agents Chemother 48, 2437-2447 | | | |
2004 | Rapid Discovery of Potent Sulfotransferase Inhibitors by Diversity-Oriented Reaction in Microplates Followed by in situ Screening | Best, M. D.; Brik, A.; Chapman, E.; Lee, L. V.; Cheng, W. C.; Wong, C. H. | Chembiochem 5, 811-819 | | | |
2003 | Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors | Brik, A.; Muldoon, J.; Lin, Y. C.; Elder, J. H.; Goodsell, D. S.; Olson, A. J.; Fokin, V. V.; Sharpless, K. B.; Wong, C. H. | Chembiochem 4, 1246-1248 | | | |
2007 | Second Generation Sugar-Assisted Ligation: An Effective New Method for the Synthesis of Cysteine-Containing Glycopeptides | Ficht, S.; Payne, R. J.; Brik, A.; Wong, C. H. | Angewandte chemie-international edition 46(31), 5975-5979 | | | |
2004 | Small molecules targeting severe acute respiratory syndrome human coronavirus | Wu, C. Y.; Jan, J. T. ; Ma, S. H.; Kuo, C. J.; Juan, H. F.; Cheng, Y. S.; Hsu, H. H.; Huang, H. C.; Wu, D.; Brik, A.; Liang, F. S.; Liu, R. S.; Fang, J. M.; Chen, S. T. ; Liang, P. H. ; Wong, C. H. | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
101(27), 10012-10017 | | | |
2006 | Strategies for the Preparation of Homogenous Glycoproteins | Brik, A.; Ficht, S.; Wong, C. -H. | CURRENT OPINION IN CHEMICAL BIOLOGY 10(6):638-644. | | | |
2008 | Sugar-assisted Glycopeptide Ligation with Complex Oligosaccharides: Scope and Limitations | Bennett, C.; Dean, S.; Payne, R.; Ficht, S.; Brik, A.; Wong, C. -H. | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 130(36), 11945-11952 | | | |
2006 | Sugar-Assisted ligation (SAL) of N-linked Glycopeptides with Broad Sequence Tolerance at the Ligation Junction | Brik, A.; Ficht, S.; Yang, Y. -Y.; Bennett, C.; Wong, C. -H. | J. Am. Chem. Soc 128(46), 15026-33 | | | |
2007 | Sugar-assisted ligation in glycoprotein synthesis | Yang, Y. Y.; Ficht, S.; Brik, A.; Wong, C. H. | J Am Chem Soc 129, 7690-7701 | | | |
2005 | Tetrabutylammonium fluoride-assisted rapid N(9)-alkylation on purine ring: Application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ. | Brik, A.; Wu, C. Y.; Best, M. D.; Wong, C. H. | Bioorganic & medicinal chemistry 13(15), 4622-4626 | | | |
2005 | Tetrabutylammonium Fluoride-Mediated Rapid Alkylation Reaction in Microtiter Plates for Discovery of Enzyme Inhibitors in Situ | Wu, C. Y.; Brik, A.; Wang, S. K.; Chen, Y. H.; Wong, C. H. | Chembiochem 6, 2176-2180 | | | |
2005 | Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ | Wu, C. Y.; Brik, A.; Wang, S. K.; Chen, Y. H.; Wong, C. H. | Chembiochem 6, 2176-2180 | | | |