Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
1997 | Catalytic Mechanism of KDO8P Synthase, Pre-Steady-State Kinetic Analysis Using Rapid Chemical Quench Flow Methods | Liang, PH ; Kohen, A; Baasov, T; Anderson, KS | Bioorg Med Chem Lett 7, 2463-2468 | | | |
1998 | Catalytic Mechanism of Kdo8P Synthase: Transient Kinetic Studies and Evaluation of a Putative Reaction Intermediate | Liang, PH ; Lewis, J; Anderson, KS; Kohen, A; D’Souza, FW; Benenson, Y; Baasov, T | Biochemistry 37, 16390-16399 | | | |
2003 | Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton | Chang, SY; Ko, TP; Liang, PH ; Wang, AHJ | The Journal of biological chemistry 278(31), 29298-29307 | | | |
2006 | Characterization and inhibition of SARS-coronavirus main protease | Liang, PH | Current Topics in Medicinal Chemistry 6, 361-376 | | | |
2004 | Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate | Kuo, CJ; Chi, YH; Hsu, JT; Liang, PH | Biochem Biophys Res Commun 318, 862-867 | | | |
2002 | Characterization of the L399P and R447G mutants of hsc70: the decrease in refolding activity is correlated with an increase in the rate of substrate dissociation | Hu, S. M.; Liang, P. H. ; Hsiao, C. D. ; Wang, C. | Arch Biochem Biophys 407(1), 135-141 | | | |
2009 | Combined Experiemntal and theoretic study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase | Lo, Chia-Hsiang; Chang, Ying-Hsuan; Wright, Jon D.; Chen, Shih-Hsun; Kan, Daphne; Lim, Carmay; Liang, Po-Huang | | | | |
2009 | Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase | Lo, CH; Chang, YH; Wright, JD; Chen, SH; Kan, D; Lim, C; Liang, PH | Journal of the American Chemical Society 131, 4051-4062 | | | |
2011 | Construction and characterization of different fusion proteins between cellulases and β-glucosidase to improve glucose production and thermostability. | Lee, HL; Chang, CK; Teng, KH; Liang, PH | BIORESOURCE TECHNOLOGY 102(4), 3973-3976 | | | |
2004 | Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination | Guo, RT; Kuo, CJ; Chou, CC; Ko, TP; Shr, HL; Liang, PH ; Wang, AHJ | The Journal of biological chemistry 279(6), 4903-4912 | | | |
2006 | Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination | Chang, TH; Guo, RT; Ko, TP; Wang, AHJ ; Liang, PH | The Journal of biological chemistry 281(21), 14991-15000 | | | |
2015 | Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. | Han, X; Chen, CC; Kuo, CJ; Huang, CH; Zheng, Y; Ko, TP; Zhu, Z; Feng, X; Wang, K; Oldfield, E; Wang, AH ; Liang, PH ; Guo, RT; Ma, Y | Proteins 83(1), 37-45 | | | |
2005 | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis | Guo, RT; Ko, TP; Chen, AP; Kuo, CJ; Wang, AHJ ; Liang, PH | Journal of Biological Chemistry 280(21), 20762-20774 | | | |
1999 | Crystallographic Studies of Phosphonat-Based alpha-reaction transition-State Analogues Complexed to Tryptophan Synthase | Sachpatzidis, A; Dealwis, C; Lubetsky, JB; Liang, PH ; Anderson, KS; Lolis, E | Biochemistry 38, 12665-12674 | | | |
2008 | Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents | Kuo, CJ; Shie, JJ; Fang, JM; Yen, GR; Hsu, JT; Liu, HG; Tseng, SN; Chang, SC; Lee, CY; Shih, SR; Liang, PH | BIOORGANIC & MEDICINAL CHEMISTRY 16, 7388-7398 | | | |
2008 | Design, Synthesis, and Evaluation of Trifluoromethyl Ketones as Inhibitors of SARS-CoV 3CL Protease | Shao, Y. -M.; Yang, W. -B. ; Kuo, T. -H.; Tsai, K. -C.; Lin, C. -H. ; Yang, A. -S. ; Liang, P. -H. ; Wong, C. -H. | Bioorganic & Medicinal Chemistry 16(8), 4652-4660 | | | |
2009 | Different reaction mechanisms for cis- and trans-prenyltransferases | Lu, Yen-Ping; Liu, Hon-Ge; Liang, Po-Huang | | | | |
2009 | Different reaction mechanisms for cis- and trans-prenyltransferases. | Lu, YP; Liu, HG; Liang, PH | Biochemical and biophysical research communications 379(2), 351-355 | | | |
2006 | Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies | Tsai, KC; Chen, SY; Liang, PH ; Lu, IL; Mahindroo, N; Hsieh, HP; Chao, YS; Liu, L; Liu, D; Lien, W; Lin, TH; Wu, SY | J Med Chem 49, 3485-3495 | | | |
2005 | Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease | Shie, JJ; Fang, JM; Kuo, CJ; Kuo, TH; Liang, PH ; Huang, HJ; Yang, WB ; Lin, CH ; Chen, JL; Wu, YT; Wong, CH | Journal of Medicinal Chemistry 48(13), 4469-4473 | | | |