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  1. Scholars Hub of the Academia Sinica
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Browsing by Author Kakadiya, R


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Showing results 1 to 20 of 20
Issue DateTitleAuthor(s)RelationscopusWOSFulltext/Archive link
2010Combination of bifunctional alkylating agent and arsenic trioxide synergistically suppresses the growth of drug-resistant tumor cells.Lee, PC; Kakadiya, R; Su, TL; Lee, TCNEOPLASIA 12(5), 376-87
2011Design, synthesis and antitumor evaluation of phenyl N-mustard-quinazoline conjugates.Marvania, B; Lee, PC; Chaniyara, R; Dong, H; Suman, S; Kakadiya, R; Chou, TC; Lee, TC; Shah, A; Su, TLBioorganic & medicinal chemistry 19(6), 1987-1998
2011Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents.Kapuriya, N; Kakadiya, R; Dong, H; Kumar, A; Lee, PC; Zhang, X; Chou, TC; Lee, TC; Chen, CH; Lam, K; Marvania, B; Shah, A; Su, TLBIOORGANIC & MEDICINAL CHEMISTRY 19(1), 471-485
2013Determination of tissue distribution of potent antitumor agent ureidomustin (BO-1055) by HPLC and its pharmacokinetic application in rats.Chien, SI; Yen, JC; Kakadiya, R; Chen, CH; Lee, TC; Su, TL; Tsai, THJournal of chromatography. B, Analytical technologies in the biomedical and life  sciences 917-918, 62-70
2012Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activityLee, PC; Lee, HJ; Kakadiya, R; Sanjiv, K; Su, TL; Lee, TCOncogene  
2011Novel 2-substituted quinolin-4-yl-benzenesulfonate derivatives: synthesis, antiproliferative activity, and inhibition of cellular tubulin polymerization.Kakadiya, R; Wu, YC; Dong, H; Kuo, HH; Yih, LH; Chou, TC; Su, TLChemMedChem 6(6), 1119-1129
-Novel Antitumor Indolizino[6,7-b]indoles with Multiple Modes of Action: DNA Cross-Linking and Topoisomerase I and II Inhibition.Chaniyara, R; Tala, S; Chen, CW; Zang, X; Kakadiya, R; Lin, LF; Chen, CH; Chien, SI; Chou, TC; Tsai, TH; Lee, TC; Shah, A; Su, TL.JOURNAL OF MEDICINAL CHEMISTRY  
2011Novel bifunctional alkylating agents, 5,10-dihydropyrrolo[1,2-b]isoquinoline derivatives, synthesis and biological activity.Chaniyara, R; Kapuriya, N; Dong, H; Lee, PC; Suman, S; Marvania, B; Chou, TC; Lee, TC; Kakadiya, R; Shah, A; Su, TLBioorganic & medicinal chemistry 19(1), 275-286
2014PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[alpha]indene Derivative in Lung Cancer Cells.Sanjiv, K; Chen, CW; Kakadiya, R; Tala, S; Suman, S; Wu, MH; Chen, YH; Su, TL; Lee, TCTranslational oncology 7(2), 256-266.e5
2009Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta[a]indenes.Kakadiya, R; Dong, H; Lee, PC; Kapuriya, N; Zhang, X; Chou, TC; Lee, TC; Kapuriya, K; Shah, A; Su, TLBioorganic & medicinal chemistry 17(15), 5614-26
2008Potent bifunctional DNA alkylating agents, derivatives of 3a-aza-cyclopenta[a]indenes against human solid tumor xenografts.Su, T. -L; Kakadiya, R; Kapuriya, N; Zhang, X; Chou, T. -C.
2010Potent DNA-directed alkylating agents. Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linkerKakadiya, R; Dong, H; Kumar, A; Narsinh, D; Zhang, X; Chou, TC; Lee, TC; Shah, A; Su, TLBIOORGANIC & MEDICINAL CHEMISTRY 18(6), 2285-2299
2010Potent DNA-directed alkylating agents: Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linker.Kakadiya, R; Dong, H; Kumar, A; Narsinh, D; Zhang, X; Chou, TC; Lee, TC; Shah, A; Su, TLBioorganic & medicinal chemistry 18(6), 2285-99
2015Repairing of N-mustard derivative BO-1055 induced DNA damage requires NER, HR, and MGMT-dependent DNA repair mechanisms.Kuo, CY; Chou, WC; Wu, CC; Wong, TS; Kakadiya, R; Lee, TC; Su, TL; Wang, HCOncotarget 6(28), 25770-83
2012Synthesis and antitumor evaluation of novel Benzo[d]pyrrolo[2,1-b]thiazole derivativesChaniyara, R; Tala, S; Chen, CW; Lee, PC; Kakadiya, R; Dong, H; Marvania, B; Chen, CH; Chou, TC; Lee, TC; Shah, A; Su, TLEur. J. Med. Chem. 53, 28-40
2012Synthesis and antitumor evaluation of novel benzo[d]pyrrolo[2,1-b]thiazole derivatives.Chaniyara, R; Tala, S; Chen, CW; Lee, PC; Kakadiya, R; Dong, H; Marvania, B; Chen, CH; Chou, TC; Lee, TC; Shah, A; Su, TLEuropean journal of medicinal chemistry 53, 28-40
2008Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.Kapuriya, N; Kapuriya, K; Zhang, X; Chou, TC; Kakadiya, R; Wu, YT; Tsai, TH; Chen, YT; Lee, TC; Shah, A; Naliapara, Y; Su, TLBioorganic & medicinal chemistry 16(10), 5413-23
2009Synthesis and in vitro cytotoxicity of 9-anilinoacridines bearing N-mustard residue on both anilino and acridine rings.Chen, CH; Lin, YW; Zhang, X; Chou, TC; Tsai, TJ; Kapuriya, N; Kakadiya, R; Su, TLEuropean journal of medicinal chemistry 44(7), 3056-9
2011Synthesis of new tetracyclic 7-oxo-pyrido[3,2,1-de]acridine derivativesChen, CH; Lin, YW; Kakadiya, R; Kumar, A; Chen, YT; Lee, TC; Su, TLTetrahedron 67(33), 5883-5893
2012The novel DNA alkylating agent BO-1090 suppresses the growth of human oral cavity cancer in xenografted and orthotopic mouse models.Sanjiv, K; Su, TL; Suman, S; Kakadiya, R; Lai, TC; Wang, HY; Hsiao, M; Lee, TCInternational Journal of Cancer 130(6), 1440-1450
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