公開日期 | 題名 | 作者 | 關聯 | scopus | WOS | 全文 |
2005 | A novel substrate binding mode revealed by the site-directed mutagenesis studies of E. coli octaprenyl pyrophosphate synthase | Kuo, CJ; Guo, RT; Li, SC; Chang, KM; Wang, AHJ ; Liang, PH | Biochemistry submitted | | | |
2011 | A pilot study on the socioeconomic valuation of conserving nationally important wetlands in Taiwan | Chen, CP ; Hsieh, HL ; Lin, HJ; Kuo, CJ; Chen, YJ; Chen, CC | | | | |
2007 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases | Guo, RT; Cao, R; Liang, PH ; Ko, TP; Chang, TH; Hudock, MP; Jeng, WY; Chen, CK; Zhang, Y; Song, Y; Kuo, CJ; Yin, F; Oldfield, E; Wang, AHJ | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(24), 10022-10027 | | | |
2004 | Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate | Kuo, CJ; Chi, YH; Hsu, JT; Liang, PH | Biochem Biophys Res Commun 318, 862-867 | | | |
2004 | Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination | Guo, RT; Kuo, CJ; Chou, CC; Ko, TP; Shr, HL; Liang, PH ; Wang, AHJ | The Journal of biological chemistry 279(6), 4903-4912 | | | |
2015 | Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. | Han, X; Chen, CC; Kuo, CJ; Huang, CH; Zheng, Y; Ko, TP; Zhu, Z; Feng, X; Wang, K; Oldfield, E; Wang, AH ; Liang, PH ; Guo, RT; Ma, Y | Proteins 83(1), 37-45 | | | |
2005 | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis | Guo, RT; Ko, TP; Chen, AP; Kuo, CJ; Wang, AHJ ; Liang, PH | Journal of Biological Chemistry 280(21), 20762-20774 | | | |
2008 | Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents | Kuo, CJ; Shie, JJ; Fang, JM; Yen, GR; Hsu, JT; Liu, HG; Tseng, SN; Chang, SC; Lee, CY; Shih, SR; Liang, PH | BIOORGANIC & MEDICINAL CHEMISTRY 16, 7388-7398 | | | |
2005 | Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease | Shie, JJ; Fang, JM; Kuo, CJ; Kuo, TH; Liang, PH ; Huang, HJ; Yang, WB ; Lin, CH ; Chen, JL; Wu, YT; Wong, CH | Journal of Medicinal Chemistry 48(13), 4469-4473 | | | |
2009 | Engineering a novel endopeptidase based on SARS 3CLpro | Kuo, CJ; Shih, YP; Kan, D; Liang, PH | BioTechniques 47(6), 1029–1032 | | | |
2004 | Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV | Hsu, JT; Kuo, CJ; Hsieh, HP; Wang, YC; Huang, KK; Lin, CP; Huang, PF; Chen, X; Liang, PH | FEBS Lett 574, 116-120 | | | |
2011 | Fluorescent substrate analog for monitoring chain elongation by undecaprenyl pyrophosphate synthase in real time. | Teng, KH; Chen, AP; Kuo, CJ; Li, YC; Liu, HG; Chen, CT; Liang, PH | Analytical biochemistry 417(1), 136-141 | | | |
2021 | Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population | Wu, LS; Huang, MC; Fann, CS ; Lane, HY; Kuo, CJ; Chiu, WC; Kwok, PY ; Cheng, AT | Translational psychiatry 11, 301 | | | |
2005 | Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures. | Sun, HY; Ko, TP; Kuo, CJ; Guo, RT; Chou, CC; Liang, PH ; Wang, AHJ | Journal of Bacteriology 187(23), 8137-8148 | | | |
2009 | Individual and common inhibitors of coronavirus and picornavirus main proteases. | Kuo, CJ; Liu, HG; Lo, YK; Seong, CM; Lee, KI; Jung, YS; Liang, PH | FEBS letters 583(3), 549-555 | | | |
2005 | Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters. | Shie, JJ; Fang, JM; Kuo, TH; Kuo, CJ; Liang, PH ; Huang, HJ; Wu, YT; Jan, JT; Cheng, YS; Wong, CH | BIOORGANIC & MEDICINAL CHEMISTRY 13, 5240-5252 | | | |
2005 | Mechanism of the maturation process of SARS-CoV 3CL protease | Hsu, MF; Kuo, CJ; Chang, KT; Chang, HC; Chou, CC; Ko, TP; Shr, HL; Chang, GG; Wang, AHJ ; Liang, PH | Journal of Biological Chemistry 280(35), 31257-31266 | | | |
2019 | Predicting clinical outcomes of cirrhosis patients with hepatic encephalopathy from the fecal microbiome. | Sung, CM; Lin, YF; Chen, KF; Ke, HM; Huang, HY; Gong, YN; Tsai, WS; Lu, MJ ; Cheng, HT; Lin, CY; Kuo, CJ; Tsai, IJ ; Hsieh, SY | Cellular and molecular gastroenterology and hepatology 8(2), 301-318.e2 | | | |
2012 | Roles of Amino Acids in the Escherichia coli Octaprenyl Diphosphate Synthase Active Site Probed by Structure-Guided Site-Directed Mutagenesis. | Chang, KM; Chen, SH; Kuo, CJ; Chang, CK; Guo, RT; Yang, JM; Liang, PH | BIOCHEMISTRY 51(6), 3412-3419 | | | |
2007 | Specific Plant Terpenoids and Lignoids Possess Potent Antiviral Activities Against Severe Acute Respiratory Syndrome Coronavirus | Wen, CC; Kuo, YH; Jan, JT; Liang, PH; Wang, SY; Liu, HG; Lee, CK; Chang, ST; Kuo, CJ; Lee, SS; Hou, CC; Hsiao, PW; Chien, SC; Shyur, LF; Yang, NS | | | | |