Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
2021 | Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir | Lo, HS; Hui, KPY; Lai, HM; He, X; Khan, KS; Kaur, S; Huang, J; Li, Z; Chan, AKN; Cheung, HH; Ng, KC; Ho, JCW; Chen, YW; Ma, B; Cheung, PM; Shin, D; Wang, K; Lee, MH; Selisko, B; Eydoux, C; Guillemot, JC; Canard, B; Wu, KP ; Liang, PH ; Dikic, I; Zuo, Z; Chan, FKL; Hui, DSC; Mok, VCT; Wong, KB; Mok, CKP; Ko, H; Aik, WS; Chan, MCW; Ng, WL | ACS central science 7(5), 792-802 | | | |
1998 | Site-Directed Mutagenesis Probing the Catalytic Role of Arginines 165 and 166 of Human Cytomegalovirus Protease | Liang, PH ; Brun, KA; Feild, JA; O’Donnell, K; Doyle, ML; Green, SM; Baker, AE; Blackburn, MN; Abdel-Meguid, SS | Biochemistry 37, 5923-5929 | | | |
2004 | Small molecules targeting severe acute respiratory syndrome human coronavirus | Wu, C. Y.; Jan, J. T. ; Ma, S. H.; Kuo, C. J.; Juan, H. F.; Cheng, Y. S.; Hsu, H. H.; Huang, H. C.; Wu, D.; Brik, A.; Liang, F. S.; Liu, R. S.; Fang, J. M.; Chen, S. T. ; Liang, P. H. ; Wong, C. H. | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
101(27), 10012-10017 | | | |
2007 | Specific Plant Terpenoids and Lignoids Possess Potent Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus | Wen, CC; Kuo, YH; Jan, JT; Liang, PH ; Wang, SY; Liu, HG; Lee, CK; Chang, ST; Kuo, CJ; Lee, SS; Hou, CC; Hsiao, PW; Chien, SC; Shyur, LF; Yang, NS | J Med Chem 50, 4087-4095 | | | |
1993 | Specificity of 4-chlorobenzoate-Coenzyme A dehalogenase catalyzed dehalogenation of halogenated aromatics | Liang, PH ; Yang, G; Dunaway-Mariano, D | Biochemistry 32, 12245-12250 | | | |
2006 | Stable benzotriazole esters as mechanism-based inhibitors of the severe acute respiratory syndrome 3CL protease | Wu, CY; King, KY; Kuo, CJ; Fang, JM; Wu, YT; Ho, MY; Liao, CL; Shie, JJ; Liang, PH ; Wong, CH | Chem Biol 13, 261-268 | | | |
2001 | Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2) | Yang, G; Kirkpatrick, RB; Ho, T; Zhang, GF; Liang, PH ; Johanson, KO; Casper, DJ; Doyle, ML; Marino, JP; Thompson, SK; Chen, W; Tew, DG; Meek, TD | Biochemistry 40, 10645-10654 | | | |
2011 | Structural and functional analysis of three β-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensis | Jeng, WY; Wang, NC; Lin, MH; Lin, CT; Liaw, YC ; Chang, WJ; Liu, CI; Liang, PH ; Wang, AHJ | Journal of structural biology 173(1), 46-56 | | | |
2009 | Structural basis of inhibition specificities of 3C and 3C-like proteases by zinc-coordinating and peptidomimetic compounds. | Lee, CC; Kuo, CJ; Ko, TP; Hsu, MF; Tsui, YC; Chang, SC; Yang, S; Chen, SJ; Chen, HC; Hsu, MC; Shih, SR; Liang, PH ; Wang, AH | The Journal of biological chemistry 284(12), 7646-7655 | | | |
2007 | Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors. | Lee, CC; Kuo, CJ; Hsu, MF; Liang, PH ; Fang, JM; Shie, JJ; Wang, AHJ | FEBS letters 581(28), 5454-5458 | | | |
2010 | Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation. | Chang, TH; Hsieh, FL; Ko, TP; Teng, KH; Liang, PH ; Wang, AHJ | The Plant Cell 22(2), 454-467 | | | |
2012 | Structure of the catalytic domain of the Clostridium thermocellum cellulase CelT | Kesavulu, MM; Tsai, JY; Lee, HL; Liang, PH ; Hsiao, CD | Acta Crystallographica Section D: Biological Crystallography D68, 310-320 | | | |
2002 | Structure, mechanism and function of prenyltransferases. | Liang, PH ; Ko, TP; Wang, AHJ | EUROPEAN JOURNAL OF BIOCHEMISTRY 269(14), 3339-3354 | | | |
2007 | Structure-Based Design and Synthesis of Highly Potent SARS-CoV 3CL Protease Inhibitors | Shao, Y. M.; Yang, W. B. ; Peng, H. P.; Hsu, M. F.; Tsai, K. C.; Kuo, T. H.; Wang, A. H. J. ; Liang, P. H. ; Lin, C. H. ; Yang, A. S. ; Wong, C. H. | ChemBioChem 8(14), 1654-1657 | | | |
2006 | Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease | Lu, IL; Mahindroo, N; Liang, PH ; Peng, YH; Kuo, CJ; Tsai, KC; Hsieh, HP; Chao, YS; Wu, SY | J Med Chem 49, 5154-5161 | | | |
2008 | Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases | Kuo, CJ; Guo, RT; Lu, IL; Liu, HG; Wu, SY; Ko, TP; Wang, AHJ ; Liang, PH | Journal of biomedicine & biotechnolog 2008, 841312 | | | |
2013 | Structures of bacterial diterpene and isoprenoid synthases: Targeting virulence and biofilm formation | Feng, Xinxin; Chan, Hsiu-Chien; Ko, Tzu-Ping; Huang, Chun-Hsiang; Hu, Yumei; Bogue, Shannon; Nakano, Chiaki; Tsutomu, Hoshino; Liang, Po-Huang ; Wang, Andrew H. -J.; Oldfield, Eric; Guo, Rey-Ting; Zhu, Wei; Li, Kai; Zheng, Yingying; Ren, Feifei; Goetz, Friedrich; Nega, Mulugeta; Jia, Shiru | | | | |
2012 | Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: A cis-prenyltransferase for bacterial peptidoglycan biosynthesis | Teng, KH; Liang, PH | BIOORGANIC CHEMISTRY 43, 51-57 | | | |
2005 | Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase. | Chen, AP; Chang, SY; Lin, YC; Sun, YS; Chen, CT; Wang, AHJ ; Liang, PH | The Biochemical journal 386(Pt 1), 169-176 | | | |
2004 | Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies | Chang, SY; Ko, TP; Chen, AP; Wang, AHJ ; Liang, PH | Protein Science 13(4), 971-978 | | | |