Issue Date | Title | Author(s) | Relation | scopus | WOS | Fulltext/Archive link |
2015 | Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms. | Han, X; Chen, CC; Kuo, CJ; Huang, CH; Zheng, Y; Ko, TP; Zhu, Z; Feng, X; Wang, K; Oldfield, E; Wang, AH ; Liang, PH ; Guo, RT; Ma, Y | Proteins 83(1), 37-45 | | | |
2005 | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis | Guo, RT; Ko, TP; Chen, AP; Kuo, CJ; Wang, AHJ ; Liang, PH | Journal of Biological Chemistry 280(21), 20762-20774 | | | |
1999 | Crystallographic Studies of Phosphonat-Based alpha-reaction transition-State Analogues Complexed to Tryptophan Synthase | Sachpatzidis, A; Dealwis, C; Lubetsky, JB; Liang, PH ; Anderson, KS; Lolis, E | Biochemistry 38, 12665-12674 | | | |
2008 | Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents | Kuo, CJ; Shie, JJ; Fang, JM; Yen, GR; Hsu, JT; Liu, HG; Tseng, SN; Chang, SC; Lee, CY; Shih, SR; Liang, PH | BIOORGANIC & MEDICINAL CHEMISTRY 16, 7388-7398 | | | |
2008 | Design, Synthesis, and Evaluation of Trifluoromethyl Ketones as Inhibitors of SARS-CoV 3CL Protease | Shao, Y. -M.; Yang, W. -B. ; Kuo, T. -H.; Tsai, K. -C.; Lin, C. -H. ; Yang, A. -S. ; Liang, P. -H. ; Wong, C. -H. | Bioorganic & Medicinal Chemistry 16(8), 4652-4660 | | | |
2009 | Different reaction mechanisms for cis- and trans-prenyltransferases | Lu, Yen-Ping; Liu, Hon-Ge; Liang, Po-Huang | | | | |
2009 | Different reaction mechanisms for cis- and trans-prenyltransferases. | Lu, YP; Liu, HG; Liang, PH | Biochemical and biophysical research communications 379(2), 351-355 | | | |
2006 | Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies | Tsai, KC; Chen, SY; Liang, PH ; Lu, IL; Mahindroo, N; Hsieh, HP; Chao, YS; Liu, L; Liu, D; Lien, W; Lin, TH; Wu, SY | J Med Chem 49, 3485-3495 | | | |
2005 | Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease | Shie, JJ; Fang, JM; Kuo, CJ; Kuo, TH; Liang, PH ; Huang, HJ; Yang, WB ; Lin, CH ; Chen, JL; Wu, YT; Wong, CH | Journal of Medicinal Chemistry 48(13), 4469-4473 | | | |
2004 | DNA Binding and Degradation by the HNH Protein ColE7 | Hsia, K. C.; Chak, K. F.; Liang, P. H. ; Cheng, Y. S.; Ku, W. Y.; Yuan, H. S. | Structure 12(2), 205-214 | | | |
2007 | Drug discovery for SARS and other human coronaviruses targeting 3C proteases | Liang, PH | Drugs of the Future 32, 29-29 | | | |
2000 | Effect of site-directed mutagenesis of the conserved aspartate and glutamate on E. coli undecaprenyl pyrophosphate synthase catalysis | Pan, JJ; Yang, LW; Liang, PH | Biochemistry 39, 13856-13861 | | | |
2009 | Engineering a novel endopeptidase based on SARS 3CLpro | Kuo, CJ; Shih, YP; Kan, D; Liang, PH | BioTechniques 47(6), 1029–1032 | | | |
2004 | Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV | Hsu, JT; Kuo, CJ; Hsieh, HP; Wang, YC; Huang, KK; Lin, CP; Huang, PF; Chen, X; Liang, PH | FEBS Lett 574, 116-120 | | | |
1995 | Evidence for Electrophilic Catalysis in the 4-Chlorobenzoyl-CoA Dehalogenase Reaction: UV, Raman and C-13 NMR Spectral Studies of Dehalogenase Complexes of Benzoyl-CoA Adducts | Taylor, KL; Liu, RQ; Liang, PH ; Price, J; Dunaway-Mariano, D; Tonge, PJ; Clarkson, J; Carey, PR | Biochemistry 34, 13881-13888 | | | |
1994 | Evidence for Nucleophilic Catalysis in the Aromatic Substitution Reaction Catalyzed by (4-Chlorobenzoyl) coenzyme A dehalogenase | Yang, G; Liang, PH ; Dunaway-Mariano, D | Biochemistry 33, 8527-8531 | | | |
2016 | Fluorescent Farnesyl Diphosphate Analogue: A Probe To Validate trans-Prenyltransferase Inhibitors. | Kuo-Hsun Teng; Erh-Ting Hsu; Ying-Hsuan Chang; Sheng-Wei Lin ; Po-Huang Liang | BIOCHEMISTRY 55(31), 4366-4374 | | | |
2011 | Fluorescent substrate analog for monitoring chain elongation by undecaprenyl pyrophosphate synthase in real time. | Teng, KH; Chen, AP; Kuo, CJ; Li, YC; Liu, HG; Chen, CT; Liang, PH | Analytical biochemistry 417(1), 136-141 | | | |
2005 | Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures. | Sun, HY; Ko, TP; Kuo, CJ; Guo, RT; Chou, CC; Liang, PH ; Wang, AHJ | Journal of Bacteriology 187(23), 8137-8148 | | | |
2003 | Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthase | Chang, SY; Chen, YK; Wang, AHJ ; Liang, PH | Biochemistry 42(49), 14452-14459 | | | |